Solitary fibrous tumor of the pleura with paraneoplastic Doege-Potter syndrome

Levitskiy A.V.

State Budgetary Healthcare Institution Moscow Multidisciplinary Clinical Center «Communarka» Moscow Healthcare Department;
N.I. Pirogov Russian National Research Medical University

ORCID: 0000-0002-3206-9892

Chemulova V.Yu.

State Budgetary Healthcare Institution Moscow Multidisciplinary Clinical Center «Communarka» Moscow Healthcare Department

ORCID: 0000-0001-6360-095X

Avdalyan A.M.

State Budgetary Healthcare Institution Moscow Multidisciplinary Clinical Center «Communarka» Moscow Healthcare Department

ORCID: 0000-0002-2229-1713

Boriskin N.V.

State Budgetary Healthcare Institution Moscow Multidisciplinary Clinical Center «Communarka» Moscow Healthcare Department

ORCID: 0000-0002-4774-7115

Ter-Ovanesov M.D.

State Healthcare Institution «Central Clinical Hospital» RZhD-Medicine

ORCID: 0000-0002-0042-1150

Mosin S.V.

State Budgetary Healthcare Institution Moscow Multidisciplinary Clinical Center «Communarka» Moscow Healthcare Department;
N.I. Pirogov Russian National Research Medical University

SPIN RSCI: 2780-1508
ORCID: 0000-0002-3722-8610

Protsenko D.N.

State Budgetary Healthcare Institution Moscow Multidisciplinary Clinical Center «Communarka» Moscow Healthcare Department;
N.I. Pirogov Russian National Research Medical University

SPIN RSCI: 1019-8216
Scopus AuthorID: 6603277055
ResearcherID: P-9224-2018
ORCID: 0000-0002-5166-3280

Solitary fibrous tumor of the pleura with paraneoplastic Doege-Potter syndrome

Authors:

Levitskiy A.V., Chemulova V.Yu., Avdalyan A.M., Boriskin N.V., Ter-Ovanesov M.D., Mosin S.V., Protsenko D.N.

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Journal: P.A. Herzen Journal of Oncology. 2023;12(6): 50‑56

DOI: 10.17116/onkolog20231206150

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To cite this article:

Levitskiy AV, Chemulova VYu, Avdalyan AM, Boriskin NV, Ter-Ovanesov MD, Mosin SV, Protsenko DN. Solitary fibrous tumor of the pleura with paraneoplastic Doege-Potter syndrome. P.A. Herzen Journal of Oncology. 2023;12(6):50‑56. (In Russ.)
https://doi.org/10.17116/onkolog20231206150

Подписка 2025 (P.A. Herzen Journal of Oncology)

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This article presents a description of a rare clinical case of a malignant variant of solitary fibrous tumor of the pleura with paraneoplastic Doege-Potter syndrome in a 74-year-old male. The disease was detected due to acute episodes of hypoglycemia. Evaluation revealed a massive intrapleural non-epithelial tumor in the right hemithorax, measuring up to 26 cm, accompanied by hypoglycemic episodes as low as 2.2 mmol/L during the night. Diagnosis was confirmed morphologically through core biopsy. The patient underwent radical surgery at the Thoracic Department of the Moscow Multidisciplinary Clinical Center «Communarka,» which included right thoracotomy, extrapleural tumor removal with atypical resection of the upper and lower lobes of the right lung. After surgical treatment, the hypoglycemic syndrome was resolved within a day. Histological and immunohistochemical analysis of the surgical specimen confirmed the malignant variant of solitary fibrous tumor of the pleura with invasion into the lung parenchyma.

Keywords:

solitary fibrous tumor of the pleura

paraneoplastic hypoglycemia

Doege-Potter syndrome

surgical treatment

Authors:

Levitskiy A.V.

State Budgetary Healthcare Institution Moscow Multidisciplinary Clinical Center «Communarka» Moscow Healthcare Department;
N.I. Pirogov Russian National Research Medical University

ORCID: 0000-0002-3206-9892

Chemulova V.Yu.

State Budgetary Healthcare Institution Moscow Multidisciplinary Clinical Center «Communarka» Moscow Healthcare Department

ORCID: 0000-0001-6360-095X

Avdalyan A.M.

State Budgetary Healthcare Institution Moscow Multidisciplinary Clinical Center «Communarka» Moscow Healthcare Department

ORCID: 0000-0002-2229-1713

Boriskin N.V.

State Budgetary Healthcare Institution Moscow Multidisciplinary Clinical Center «Communarka» Moscow Healthcare Department

ORCID: 0000-0002-4774-7115

Ter-Ovanesov M.D.

State Healthcare Institution «Central Clinical Hospital» RZhD-Medicine

ORCID: 0000-0002-0042-1150

Mosin S.V.

State Budgetary Healthcare Institution Moscow Multidisciplinary Clinical Center «Communarka» Moscow Healthcare Department;
N.I. Pirogov Russian National Research Medical University

SPIN RSCI: 2780-1508
ORCID: 0000-0002-3722-8610

Protsenko D.N.

State Budgetary Healthcare Institution Moscow Multidisciplinary Clinical Center «Communarka» Moscow Healthcare Department;
N.I. Pirogov Russian National Research Medical University

SPIN RSCI: 1019-8216
Scopus AuthorID: 6603277055
ResearcherID: P-9224-2018
ORCID: 0000-0002-5166-3280

Received:

09.03.2023

Accepted:

18.05.2023

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