Surgery in Patients with Renal Cell Carcinoma and Tumor Thrombus of Inferior Vena Cava

Chervyakov Yu.V.

Yaroslavl State Medical University;
Yaroslavl Regional Clinical Hospital

ORCID: 0000-0001-5270-9968

Komlev D.L.

Yaroslavl Regional Clinical Hospital

ORCID: 0000-0003-4180-5326

Staroverov I.N.

Yaroslavl State Medical University;
Yaroslavl Regional Clinical Hospital

ORCID: 0000-0001-9855-9467

Lonchakova O.M.

Yaroslavl State Medical University;
Yaroslavl Regional Clinical Hospital

ORCID: 0000-0003-4507-6693

Pamputis S.N.

Yaroslavl Regional Clinical Hospital

ORCID: 0000-0002-7880-1081

Zavyalov D.V.

Yaroslavl Regional Clinical Hospital

ORCID: 0000-0002-9173-6878

Baranov G.A.

Russian University of Medicine

ORCID: 0000-0003-1394-4185

Surgery in Patients with Renal Cell Carcinoma and Tumor Thrombus of Inferior Vena Cava

Authors:

Chervyakov Yu.V., Komlev D.L., Staroverov I.N., Lonchakova O.M., Pamputis S.N., Zavyalov D.V., Baranov G.A.

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Journal: Journal of Venous Disorders. 2024;18(3): 207‑213

DOI: 10.17116/flebo202418031207

Downloaded: 5

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To cite this article:

Chervyakov YuV, Komlev DL, Staroverov IN, Lonchakova OM, Pamputis SN, Zavyalov DV, Baranov GA. Surgery in Patients with Renal Cell Carcinoma and Tumor Thrombus of Inferior Vena Cava. Journal of Venous Disorders. 2024;18(3):207‑213. (In Russ.)
https://doi.org/10.17116/flebo202418031207

Подписка 2025 (Journal of Venous Disorders)

Использование инфографики авторами научных работ

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OBJECTIVE

To present surgical treatment of patients with renal cell carcinoma complicated by tumor thrombosis of inferior vena cava.

MATERIAL AND METHODS

Surgical interventions were performed in 21 patients (mean age 59 years) with renal cell carcinoma T3b and T3c, N0-1, M0 stage. There were 17 (81%) men and 4 (19%) women. Tumor thrombosis of inferior vena cava arose from the right kidney in 16 (76%) cases and left kidney in 5 (24%) cases. All patients underwent nephrectomy and different types of thrombectomy from inferior vena cava with subsequent lymph node dissection. All patients received postoperative anticoagulant therapy.

RESULTS

Inferior vena cava patency was restored in all cases. Postoperative mortality was 9.5%. We estimated treatment outcomes throughout a year in 84% of cases. Thrombotic recurrent occlusion of infrarenal IVC occurred in 2 out of 5 patients. There was no recurrent thrombosis of suprarenal IVC and contralateral renal vein. Fatal outcome occurred in 4 patients in 5, 7, 8 and 11 months after surgery from progression of cancer. Annual survival rate was 75%.

CONCLUSION

Surgery for renal cell carcinoma complicated by tumor thrombosis of IVC should include vein recanalization. This intervention is relatively safe and associated with higher annual survival.

Keywords:

kidney cancer

inferior vena cava

tumor thrombus

surgery

VTE

Authors:

Chervyakov Yu.V.

Yaroslavl State Medical University;
Yaroslavl Regional Clinical Hospital

ORCID: 0000-0001-5270-9968

Komlev D.L.

Yaroslavl Regional Clinical Hospital

ORCID: 0000-0003-4180-5326

Staroverov I.N.

Yaroslavl State Medical University;
Yaroslavl Regional Clinical Hospital

ORCID: 0000-0001-9855-9467

Lonchakova O.M.

Yaroslavl State Medical University;
Yaroslavl Regional Clinical Hospital

ORCID: 0000-0003-4507-6693

Pamputis S.N.

Yaroslavl Regional Clinical Hospital

ORCID: 0000-0002-7880-1081

Zavyalov D.V.

Yaroslavl Regional Clinical Hospital

ORCID: 0000-0002-9173-6878

Baranov G.A.

Russian University of Medicine

ORCID: 0000-0003-1394-4185

Received:

18.12.2023

Accepted:

15.03.2024

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