The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-4329
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Volkova Yu.I.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Zikiryakhodzhaev A.D.

I.M. Sechenov First Moscow State Medical University (Sechenov University) of the Ministry of Russia;
P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Russia;
Peoples’ Friendship University of Russia

Volchenko N.N.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Kazaryan L.P.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia;
I.M. Sechenov First Moscow State Medical University of the Ministry of Health of Russia

Starkova M.V.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Dzhabrailova D.Sh.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Maksimov K.V.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Diagnosis of the sentinel lymph node during neoadjuvant chemotherapy

Authors:

Volkova Yu.I., Zikiryakhodzhaev A.D., Volchenko N.N., Kazaryan L.P., Starkova M.V., Dzhabrailova D.Sh., Maksimov K.V.

More about the authors

Journal: P.A. Herzen Journal of Oncology. 2021;10(6): 100‑105

DOI: 10.17116/onkolog202110061100

Read: 1206 times

Download PDF (RU)
Contact the author
Table of contents

DIAGNOSIS OF THE SENTINEL LYMPH NODE DURING NEOADJUVANT CHEMOTHERAPY
DIAGNOSIS OF THE SENTINEL LYMPH NODE DURING NEOADJUVANT CHEMOTHERAPY

To cite this article:

Volkova YuI, Zikiryakhodzhaev AD, Volchenko NN, Kazaryan LP, Starkova MV, Dzhabrailova DSh, Maksimov KV. Diagnosis of the sentinel lymph node during neoadjuvant chemotherapy. P.A. Herzen Journal of Oncology. 2021;10(6):100‑105. (In Russ.)
https://doi.org/10.17116/onkolog202110061100

Подписка 2026 Онкология. Журнал им. П.А. Герцена (P.A. Herzen Journal of Oncology)
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Recommended articles:
Capsular contracture after reco­nstructive plastic surgery for breast cancer. P.A. Herzen Journal of Onco­logy. 2024;(6):78-83
Neoadjuvant drug therapy and onco­logical outcomes in patients with stage I–II breast cancer. P.A. Herzen Journal of Onco­logy. 2025;(1):5-12
The role of neoadjuvant chemotherapy in the combined treatment of loca­lly adva­nced non-small cell lung cancer and the prerequisites for a personalized approach to it. P.A. Herzen Journal of Onco­logy. 2025;(1):19-25
NDRG1 protein expression in breast cancer samples, rela­tionship with lymph nodes meta­stasis. Russian Journal of Archive of Pathology. 2024;(6):36-42
Impact of tumor size on actuarial survival of patients with primary breast sarcoma: a case-control study. Piro­gov Russian Journal of Surgery. 2024;(12):38-43
Asse­ssment of risk factors for breast cancer deve­lopment in women living in the Sara­tov region. Russian Bulletin of Obstetrician-Gynecologist. 2024;(6):100-106
Left ventricular myocardial performance index (Tei index) as an early marker of cardiotoxicity in anti­tumor therapy. Russian Cardiology Bulletin. 2024;(4-2):137-143
Nottingham Prognostic Index rela­tion to cyto­kine-producing tumor mole­cular subtypes in breast cancer. Russian Journal of Preventive Medi­cine. 2025;(1):63-68
The possibilities of predicting and redu­cing the risk of breast cancer in women against the background of the use of assi­sted reproductive technologies. Russian Bulletin of Obstetrician-Gynecologist. 2025;(1):59-64
The effect of acetylamide synthetic peptide HLDF-6 on cell differentiation in breast cancer. Russian Journal of Archive of Pathology. 2025;(2):5-10
Abstract:

The indications for chemotherapy have now significantly expanded at the first stage of chemotherapy. Neoadjuvant chemotherapy has shown its efficiency in treating not only locally advanced breast cancer, but also its primary resectable forms. In connection with this trend, the question of the optimal timing of a sentinel lymph node biopsy (SLNB) has arisen. This paper discusses the advantages and disadvantages of SLNB before or after neoadjuvant chemotherapy.

Keywords:

breast cancer
sentinel lymph node biopsy
neoadjuvant chemotherapy

Authors:

Volkova Yu.I.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Zikiryakhodzhaev A.D.

I.M. Sechenov First Moscow State Medical University (Sechenov University) of the Ministry of Russia;
P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Russia;
Peoples’ Friendship University of Russia

Volchenko N.N.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Kazaryan L.P.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia;
I.M. Sechenov First Moscow State Medical University of the Ministry of Health of Russia

Starkova M.V.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Dzhabrailova D.Sh.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Maksimov K.V.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Received:

12.05.2021

Accepted:

18.05.2021

Close metadata

References:

  1. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A cancer journal for clinicians. 2018;68(6):394-424.  https://doi.org/10.3322/caac.21492
  2. Petrova GV, Starinsky VV, Gretsova OP, Shakhzadova AO, Samsonov YuV. Cancer care to the population of Russia in 2017 according to the data of federal statistical observation. P.A. Herzen Journal of Oncology= Onkologiya. Zhurnal imeni P.A. Gertsena. 2019;8(1):32-40. (In Russ.). https://doi.org/10.17116/onkolog2019801132
  3. Fisher B, Redmond C, Poisson R, Margolese R, Wolmark N, Wickerham L, Sidorovich L. Eight-year results of a randomized clinical trial comparing total mastectomy and lumpectomy with or without irradiation in the treatment of breast cancer. New England Journal of Medicine. 1989;320(13):822-828.  https://doi.org/10.1056/NEJM198903303201302
  4. Fisher B, Anderson S, Bryant J, Margolese RG, Deutsch M, Fisher ER, Wolmark N. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. New England Journal of Medicine. 2002;347(16):1233-1241. https://doi.org/10.1056/NEJMoa022152
  5. Veronesi U, Saccozzi R, Del Vecchio M, Banfi A, Clemente C, De Lena M, Zucali R. Comparing radical mastectomy with quadrantectomy, axillary dissection, and radiotherapy in patients with small cancers of the breast. New England Journal of Medicine. 1981;305(1):6-11.  https://doi.org/10.1056/NEJM198107023050102
  6. Veronesi U, Cascinelli N, Mariani L, Greco M, Saccozzi R, Luini A, Marubini E. Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer. New England Journal of Medicine. 2002;347(16):1227-1232. https://doi.org/10.1056/NEJMoa020989
  7. Krishnamurthy S, Sneige N, Bedi DG, Edieken BS, Fornage BD, Kuerer HM, Hunt KK. Role of ultrasound‐guided fine‐needle aspiration of indeterminate and suspicious axillary lymph nodes in the initial staging of breast carcinoma. Cancer. 2002;95(5):982-988. 
  8. Oruwari JU, Chung MA, Koelliker S, Steinhoff MM, Cady B. Axillary staging using ultrasound-guided fine needle aspiration biopsy in locally advanced breast cancer. The American journal of surgery. 2002;184(4):307-309.  https://doi.org/10.1002/cncr.10786
  9. Bedrosian I, Reynolds C, Mick R, Callans LS, Grant CS, Donohue JH, Czerniecki BJ. Accuracy of sentinel lymph node biopsy in patients with large primary breast tumors. Cancer: Interdisciplinary International Journal of the American Cancer Society. 2000;88(11):2540-2545. https://doi.org/10.1002/1097-0142(20000601)88:11<2540::AID-CNCR16>3.0.CO;2-A "> 3.0.CO;2-A" target="_blank">https://doi.org/10.1002/1097-0142(20000601)88:11<2540::AID-CNCR16>3.0.CO;2-A
  10. Boileau JF, Poirier B, Basik M, Holloway CM, Gaboury L, Sideris L, Meterissian S, Arnaout A, Brackstone M, McCready DR, Karp SE, Trop I, Lisbona A, Wright FC, Younan RJ, Provencher L, Patocskai E, Omeroglu A, Robidoux A. Sentinel node biopsy after neoadjuvant chemotherapy in biopsy-proven node-positive breast cancer: the SN FNAC stud. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. 2015;33(3):258-264.  https://doi.org/10.1200/JCO.2014.55.7827
  11. Mansel RE, Fallowfield L, Kissin M, Goyal A, Newcombe RG, Dixon JM, Ell PJ. Randomized multicenter trial of sentinel node biopsy versus standard axillary treatment in operable breast cancer. the ALMANAC Trial. Journal of the National Cancer Institute. 2006;98(9):599-609.  https://doi.org/10.1093/jnci/djj158
  12. Purushotham AD, Upponi S, Klevesath MB, Bobrow L, Millar K, Myles JP, Duffy SW. Morbidity after sentinel lymph node biopsy in primary breast cancer: results from a randomized controlled trial. Journal of clinical oncology. 2005;23(19):4312-4321. https://doi.org/10.1200/JCO.2005.03.228
  13. Krag DN, Anderson SJ, Julian TB, Brown AM, Harlow SP, Costantino JP, Wolmark N. Sentinel-lymph-node resection compared with conventional axillary-lymph-node dissection in clinically node-negative patients with breast cancer: overall survival findings from the NSABP B-32 randomised phase 3 trial. The lancet oncology. 2010;11(10):927-933.  https://doi.org/10.1016/S1470-2045(10)70207-2
  14. Kuehn T, Bauerfeind I, Fehm T, Fleige B, Hausschild M, Helms G, Untch M. Sentinel-lymph-node biopsy in patients with breast cancer before and after neoadjuvant chemotherapy (SENTINA): a prospective, multicentre cohort study. The lancet oncology. 2013;14(7):609-618.  https://doi.org/10.1016/S1470-2045(13)70166-9
  15. Zetterlund L, Celebioglu F, Axelsson R, de Boniface J, Frisell J. Swedish prospective multicenter trial on the accuracy and clinical relevance of sentinel lymph node biopsy before neoadjuvant systemic therapy in breast cancer. Breast cancer research and treatment. 2017;163(1):93-101.  https://doi.org/10.1007/s10549-017-4163-2
  16. Stenina MB, Zhukova LG, Koroleva IA, Parokonnaya AA, Semiglazova TY, Tyulyandin SA., Frolova MA. Practical Guidelines for the Treatment of Invasive Breast Cancer. Malignant tumors. 2019;9(9):128-163. (In Russ.). https://doi.org/10.18027 / 2224-5057-2020-10-3s2-09
  17. Cardoso F, Kyriakides S, Ohno S, Penault-Llorca F, Poortmans P, Rubio IT, Senkus E. Early breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Annals of Oncology. 2019;30(8):1194-1220. https://doi.org/10.1093/annonc/mdz394.003
  18. Goetz MP, Gradishar WJ, Anderson BO, Abraham J, Aft R, Allison KH, Kumar R. Breast cancer, version 3.2018 featured updates to the NCCN guidelines. JNCCN Journal of the National Comprehensive Cancer Network. 2019;17(2):118-126.  https://doi.org/10.6004/jnccn.2019.0009
  19. Lyman GH, Somerfield MR, Bosserman LD, Perkins CL, Weaver DL, Giuliano AE. Sentinel lymph node biopsy for patients with early-stage breast cancer: American Society of Clinical Oncology clinical practice guideline update. Journal of Clinical Oncology. 2017;35(5):561-564.  https://doi.org/10.1200/JCO.2013.54.1177
  20. Curigliano G, Burstein HJ, Winer EP, Gnant M, Dubsky P, Loibl S, Xu B. De-escalating and escalating treatments for early-stage breast cancer: the St. Gallen International Expert Consensus Conference on the Primary Therapy of Early Breast Cancer 2017. Annals of Oncology. 2017;28(8):1700-1712. https://doi.org/10.1093/annonc/mdx308
  21. Boughey JC, Suman VJ, Mittendorf EA, Ahrendt GM, Wilke LG, Taback B, Alliance for Clinical Trials in Oncology. Sentinel lymph node surgery after neoadjuvant chemotherapy in patients with node-positive breast cancer: the ACOSOG Z1071 (Alliance) clinical trial. Jama. 2013;310(14):1455-1461. https://doi.org/10.1001/jama.2013.278932
  22. Choi HJ, Kim I, Alsharif E, Park S, Kim JM, Ryu JM, Lee JE. Use of sentinel lymph node biopsy after neoadjuvant chemotherapy in patients with axillary node-positive breast cancer in diagnosis. Journal of breast cancer. 2018;21(4):433-441.  https://doi.org/10.1245/s10434-013-2992-8
  23. Donker M, van Tienhoven G, Straver ME, Meijnen P, van de Velde CJ, Mansel RE, Rutgers EJ. Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer (EORTC 10981-22023 AMAROS): a randomised, multicentre, open-label, phase 3 non-inferiority trial. The Lancet Oncology. 2014;15(12):1303-1310. https://doi.org/10.1016/S1470-2045(14)70460-7
  24. Classe JM, Loaec C, Gimbergues P, Alran S, de Lara CT, Dupre PF, Campion L. Sentinel lymph node biopsy without axillary lymphadenectomy after neoadjuvant chemotherapy is accurate and safe for selected patients: the GANEA 2 study. Breast cancer research and treatment. 2019;173(2):343-352.  https://doi.org/10.1007/s10549-018-5004-7
  25. Fayanju OM, Ren Y, Thomas SM, Greenup RA, Plichta JK, Rosenberger LH, Hwang ES. The clinical significance of breast-only and node-only pathologic complete response (pCR) after neoadjuvant chemotherapy (NACT): a review of 20,000 breast cancer patients in the National Cancer Data Base (NCDB). Annals of surgery. 2018;268(4):591.  https://doi.org/10.1097/SLA.0000000000002953
  26. Nogi H, Uchida K, Mimoto R, Kamio M, Shioya H, Toriumi Y, Takeyama H. Long-term follow-up of node-negative breast cancer patients evaluated via sentinel node biopsy after neoadjuvant chemotherapy. Clinical breast cancer. 2017;17(8):644-649.  https://doi.org/10.1016/j.clbc.2017.05.002
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.