The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Gevorkov A.R.

P.A. Herzen Moscow Oncology Research Institute, Ministry of Health of Russia, Moscow, Russian Federation

Bojko A.V.

GBOU VPO «Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet» Minzdrava Rossii, Tomsk

Bolotina L.V.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdravsotsrazvitiia Rossii

Shashkov S.V.

P.A. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center, Ministry of Health of Russia, Moscow, Russia

Features of therapy accompanying the radiation treatment of patients with head and neck tumors

Authors:

Gevorkov A.R., Bojko A.V., Bolotina L.V., Shashkov S.V.

More about the authors

Journal: P.A. Herzen Journal of Oncology. 2019;8(4): 282‑288

DOI: 10.17116/onkolog20198041282

Views: 2813

Downloaded: 120

Download PDF (RU)
Contact the author
Table of contents

FEATURES OF THERAPY ACCOMPANYING THE RADIATION TREATMENT OF PATIENTS WITH HEAD AND NECK TUMORS
FEATURES OF THERAPY ACCOMPANYING THE RADIATION TREATMENT OF PATIENTS WITH HEAD AND NECK TUMORS

To cite this article:

Gevorkov AR, Bojko AV, Bolotina LV, Shashkov SV. Features of therapy accompanying the radiation treatment of patients with head and neck tumors. P.A. Herzen Journal of Oncology. 2019;8(4):282‑288. (In Russ.)
https://doi.org/10.17116/onkolog20198041282

 
Подписка 2025-2 (P.A. Herzen Journal of Oncology)
МСФ на ЯМ
Close metadata
Recommended articles:
Resu­lts of the impact of personalized reha­bilitation on the quality of life of men after lapa­roscopic prostatectomy. P.A. Herzen Journal of Onco­logy. 2024;(4):22-28
Hypo­fractionate radiotherapy for a rare mali­gnant neoplasm of epidermal origin — kera­toacanthoma of the skin. P.A. Herzen Journal of Onco­logy. 2024;(4):48-53
To study the effe­ctiveness and impact on the quality of life of patients with subclinical and clinically pronounced anxiety diso­rder of a mobile application in combination with Adaptol therapy. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(7):98-105
On the issue of opti­mizing protein and energy supply for patients with acute cere­brovascular acci­dent. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(8-2):51-55
Tole­rability of multiphasic and mono­phasic combined hormonal contraceptives patients with uterine fibroids. Russian Journal of Human Reproduction. 2024;(4):78-89
Drug therapy for loca­lly adva­nced and meta­static non-small cell lung cancer with MET muta­tion: indi­rect comparison. Medi­cal Technologies. Asse­ssment and Choice. 2024;(3):82-92
The Russian consensus on the treatment of intrahepatic cholangiocarcinoma. Piro­gov Russian Journal of Surgery. 2024;(10):7-20
Choice of fractionation regi­men for Grade IV gliomas depe­nding on rapid early progression. Burdenko's Journal of Neurosurgery. 2024;(5):23-29
Disease-free survival after surgical and combined treatment of newly diagnosed craniopharyngiomas in adults. Burdenko's Journal of Neurosurgery. 2024;(5):54-59
Factors affe­cting the quality of life of patients with neurological mani­festations of post-COVID syndrome. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(9):44-50

The publication highlights the main issues of tolerability of simultaneous radiotherapy and targeted therapy in patients with head and neck tumors. The clinical case example is used to show the course of side effects and to discuss the key issues of preparation for treatment and accompanying therapy. The authors describe the patient’s status in late periods and discuss whether there is a relationship of the adequate management of early reactions to the delayed state and quality of life in patients.

Keywords:

accompanying therapy
head and neck tumors
radiation therapy
targeted therapy
mucositis
bioradiation dermatitis
acne-like rash
nutritional support
quality of life

Authors:

Gevorkov A.R.

P.A. Herzen Moscow Oncology Research Institute, Ministry of Health of Russia, Moscow, Russian Federation

Bojko A.V.

GBOU VPO «Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet» Minzdrava Rossii, Tomsk

Bolotina L.V.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdravsotsrazvitiia Rossii

Shashkov S.V.

P.A. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center, Ministry of Health of Russia, Moscow, Russia

List of references:

  1. The Global Burden of Cancer 2015. Global Burden of Disease Cancer Collaboration. Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-years for 32 Cancer Groups, 1990 to 2015.A Systematic Analysis for the Global Burden of Disease Study. JAMA Oncol. 2017;3(4):524-548. https://doi.org/10.1001/jamaoncol.2016.5688
  2. Barrera R. Nutritional support in cancer patients. JPEN J Parenter Enteral Nutr. 2002;26(5, Suppl.):S63-S71. https://doi.org/10.1177/014860710202600516
  3. Bloch A. Nutrition support in cancer. Semin Oncol Nurs. 2000;16(2):122-127. https://doi.org/10.1053/on.2000.5555
  4. Bozzetti F, Gavazzi C, Miceli R, et al. Perioperative total parenteral nutrition in malnourished, gastrointestinal cancer patients: a randomized, clinical trial. J Parenter Enteral Nutr. 2000;24(1):7-14. https://doi.org/10.1177/014860710002400107
  5. Bozzetti F. Nutrition and gastrointestinal cancer. Curr Opin Clin Nutr Metab Care. 2001;4(6):541-546. https://doi.org/10.1097/00075197-200111000-00014
  6. Langius J, Doornaert P, Spreeuwenberg M, Langendijk J, Leemans C, Schueren M. Radiotherapy on the neck nodes predicts severe weight loss in patients with early stage laryngeal cancer. Radiother Oncol. 2010;97(1):80-85. https://doi.org/10.1016/j.radonc.2010.02.017
  7. Matthews TW, Lampe HB, Dragosz K. Nutritional status in head and neck cancer patients. J Otolaryngol. 1995;24(2):87-91.
  8. Unsal D, Mentes B, Akmansu M, Uner A, Oguz M, Pak Y. Evaluation of nutritional status in cancer patients receiving radiotherapy. Am J Clin Oncol. 2006;29(2):183-188. https://doi.org/10.1097/01.coc.0000198745.94757.ee
  9. Meyer F, Fortin A, Wang C, Liu G, Bairati I. Predictors of severe acute and late toxicities in patients with localized head-and-neck cancer treated with radiation therapy. Int J Radiat Oncol Biol Phys. 2012;82(4):1454-1462. https://doi.org/10.1016/j.ijrobp.2011.04.022
  10. Capuano G, Grosso A, Gentile P, et al. Influence of weight loss on outcomes in patients with head and neck cancer undergoing concomitant chemoradiotherapy. Head Neck. 2008;30(4):503-508. https://doi.org/10.1002/hed.20737
  11. Kiseleva ES, ed. Luchevaya terapiya zlokachestvennykh opukholei. Rukovodstvo dlya vrachei. Moscow: Meditsina, 1996. (In Russ.)
  12. Sokurenko VP, Korytova LI. Bochkareva TN. Opyt konformnoi luchevoi terapii bol’nykh s opukholyami orofaringeal’noi zony. Meditsinskaya fizika. 2009; 41(1):39. (In Russ.)
  13. Lalla R, Sonis S, Peterson D. Management of oral mucositis in patients who have cancer. Dent Clin North Am. 2008;52(1):61-77. https://doi.org/10.1016/j.cden.2007.10.002
  14. Li Y, Taylor J, Ten Haken R, Eisbruch A. The impact of dose on parotid salivary recovery in head and neck cancer patients treated with radiation therapy. Int J Radiat Oncol Biol Phys. 2007;67(3):660-669. https://doi.org/10.1016/j.ijrobp.2006.09.021
  15. Rosenthal D, Trotti A. Strategies for managing radiation-induced mucositis in head and neck cancer. Semin Radiat Oncol. 2009;19(1):29-34. https://doi.org/10.1016/j.semradonc.2008.09.006
  16. Campos MI, Campos CN, Aarestrup FM, Aarestrup BJ. Oral mucositis in cancer treatment: Natural history, prevention and treatment. Mol Clin Oncol. 2014;2(3):337-340. https://doi.org/10.3892/mco.2014.253
  17. Scully C, Epstein J, Sonis S. Oral mucositis: A challenging complication of radiotherapy, chemotherapy, and radiochemotherapy. Part 2: Diagnosis and management of mucositis. Head Neck. 2004;26(1):77-84. https://doi.org/10.1002/hed.10326
  18. Argiris A, Brockstein BE, Haraf DJ, Stenson KM, Mittal BB, Kies MS, Rosen FR, Jovanovic B, Vokes EE. Competing causes of death and second primary tumors in patients with locoregionally advanced head and neck cancer treated with chemoradiotherapy. Clin Cancer Res. 2004;10(6):1956-1962. https://doi.org/10.1158/1078-0432.ccr-03-1077
  19. Epstein JB, Thariat J, Bensadoun RJ. Oral complications of cancer and cancer therapy: from cancer treatment to survivorship. CA Cancer J Clin. 2012;62(6):400-422.
  20. McQuestion M. Evidence-based skin care management in radiation therapy. Semin Oncol Nurs. 2006;22(3):163-173. https://doi.org/10.1016/j.soncn.2006.04.004
  21. Feight D, Baney, T, Bruce S, McQuestion M. Putting evidence into practice. Clin J Oncol Nurs. 2011;15(5):481-492. https://doi.org/10.1188/11.CJON.481-492
  22. Schnur JB, Quellette SC, DiLorenzo TA, Green S, Montgomery GH. A qualitative analysis of acute skin toxicity among breast cancer radiotherapy patients. Psychooncology. 2011;20(3):260-268. https://doi.org/10.1002/pon.1734
  23. Hymes SR, Strom EA, Fife C. Radiation dermatitis: clinical presentation, pathophysiology, and treatment. J Am Acad Dermatol. 2006;54:28-46. https://doi.org/10.1016/j.jaad.2005.08.054

Close metadata

Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.