Detection of magnesium deficiency, including subclinical at the stage of preparation of the patient for surgical treatment, during surgery, in the postoperative period is very important. Determination of the level of magnesium in serum or blood plasma is carried out in serum or blood plasma, very rarely in the urine. Solutionsto (study saliva) expands diagnostic and treatment possibilities in clinical practice. Allows you to receive biomaterial from the patient without involving medical personnel for venopuncture. The literature presents data on the determination of the level of magnesium in saliva in cardiac patients with mitral valve prolapse, ischemic heart disease of 2-3 functional classes. The paper presents data for determining the level of magnesium in serum, blood plasma, and saliva in patients who underwent open-heart surgery (before surgery and 7 days after surgery). The possibility of determining the level of magnesium in saliva for the diagnosis of subclinical magnesium deficiency in a load test is considered.
OBJECTIVE
Compare the indicators of magnesium content in serum, blood plasma, and saliva and evaluate their dynamics in patients with cardiac surgery after open heart surgery.
MATERIAL AND METHODS
The pilot study included 17 patients. The level of magnesium in the substrates (serum, blood plasma, saliva) was measured before surgery and 7 days after surgery. The control group consisted of 10 practically healthy volunteers. The magnesium level was determined by photometric method (with xylidine blue).
RESULTS
There were no statistically significant differences when comparing magnesium values in serum, blood plasma, and saliva between the control groups and patients, as well as in the group of patients in dynamics. The correlation coefficient of magnesium in saliva and blood plasma was 0.79, and magnesium in serum and saliva was 0.68.
CONCLUSION
The correlation of magnesium values in various biosubstrates allows us to recommend the determination of magnesium in saliva for dynamic monitoring of patients both at the stage of preparation for surgery and in the postoperative period. Further research is needed.
