Clinical efficacy evaluation of a multivitamin combined reparative drug for local use in the complex therapy of eczema

Silina L.V.; Kharakhordina Yu.E.; Esipova E.A.; Karpova A.V.

doi:https://doi.org/10.17116/klinderma20212001162

Silina L.V.

Kursk State Medical University (KSMU)

Kharakhordina Yu.E.

Kursk State Medical University (KSMU)

Esipova E.A.

Kursk State Medical University (KSMU)

Karpova A.V.

Peoples Friendship University of Russia;
Joint-stock company Pharmaceutical enterprise «Retinoids»

Clinical efficacy evaluation of a multivitamin combined reparative drug for local use in the complex therapy of eczema

Authors:

Silina L.V., Kharakhordina Yu.E., Esipova E.A., Karpova A.V.

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Journal: Russian Journal of Clinical Dermatology and Venereology. 2021;20(1): 62‑70

DOI: 10.17116/klinderma20212001162

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To cite this article:

Silina LV, Kharakhordina YuE, Esipova EA, Karpova AV. Clinical efficacy evaluation of a multivitamin combined reparative drug for local use in the complex therapy of eczema. Russian Journal of Clinical Dermatology and Venereology. 2021;20(1):62‑70. (In Russ.)
https://doi.org/10.17116/klinderma20212001162

Подписка 2026 Клиническая дерматология и венерология (Russian Journal of Clinical Dermatology and Venereology)

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PROBLEM RELEVANCE

The share increase of eczema in the structure of dermatological pathology is steadily progressive. The largest number of patients is people of working age and there is a tendency to an increase in the severity of the pathological process and a decrease in the inter-relapse period with an increase in the length of the disease. Long-term remission is believed to optimize the pathology course and improve the patient’s life quality with eczema.

OBJECTIVE

To evaluate the effectiveness of multivitamin combined reparative ointment in the complex therapy of true eczema.

MATERIAL AND METHODS

The effect of multivitamin combined reparative ointment on the duration of the inter-relapse period was studied in 80 patients with chronic true eczema at the age of 25—55 years.

RESULTS

In patients of the main group, an increase in the duration of remission was observed on average up to 4 months a decrease in the severity of the clinical picture with a subsequent exacerbation and decrease in the indicators of the dermatological quality of life index. In addition, in patients who used multivitamin combined reparative ointment during remission the condition of the skin improved; there were no serious side-effects.

CONCLUSION

The use of multivitamin combined reparative ointment in the inter-relapse period of eczema reduces the severity of subjective and objective manifestations of the eczematous process.

Keywords:

eczema

therapy

retinol palmitate

α-tocopherol acetate

colecalciferol

multivitamin reparative ointment

Authors:

Silina L.V.

Kursk State Medical University (KSMU)

Kharakhordina Yu.E.

Kursk State Medical University (KSMU)

Esipova E.A.

Kursk State Medical University (KSMU)

Karpova A.V.

Peoples Friendship University of Russia;
Joint-stock company Pharmaceutical enterprise «Retinoids»

Received:

01.12.2020

Accepted:

13.01.2020

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