BACKGROUND
Microbial eczema affects 12–27% of patients from all types of eczematous dermatoses. Analyzing data from 2009 to 2010, there was found a tendency for more severe forms of dermatosis, more frequent relapses, more wide areas of skin involved and resistance to the conventional treatment. Chronic and recurrent microbial eczema affects the quality of life of the patients. The key point in microbial eczema pathogenesis is an immune dysfunction with hyper-reactivity to the chronic infectious stimulation. Staphylococcus aureus has been proposed as a cause of microbial eczema by acting as a super-antigen. According to the WHO report (30.04.14), there are about 60–80% of Staphylococcus aureus strains resistant to commonly prescribed antibiotics.
OBJECTIVE
To evaluate the efficacy of phototherapy usage in patients with microbial eczema.
MATERIALS AND METHODS
60 patients with microbial eczema (34 females and 26 males aged 32–79 years) were examined and treated. 30 patients were treated with classical therapy, including broad-spectrum antibiotics; and 30 patients were treated with therapy including narrow-band UV-B without broad-spectrum antibiotics usage. The efficacy or treatment was evaluated due to physical examination and immunological criteria in 21 days. The research findings were processed using the Statistica 10.0 portable (StatSoft) and Microsoft Excel 2016.
RESULTS
Both groups of patients demonstrated normalization of the cell and humoral immunity.
CONCLUSION
The method of patients’ treatment with microbial eczema using narrow-band UV-B excluding broad-spectrum antibiotics usage is comparable with the therapy including broad-spectrum antibiotics however without its side-effects.