Application of multifunctional apparatuses and combined skin quality improvement protocols is becoming increasingly popular.

OBJECTIVE

To determine the efficacy and safety of combined application of hyaluronic acid-based dermal implants, narrow-band pulsed light technology and non-ablative fractional photothermolysis.

MATERIAL AND METHODS

The study involved 25 healthy volunteers aged 35—65 years. Randomization method was used to select 5 groups of 5 participants. In group I, a comprehensive correction was performed (skin preparation with biorevitalizants, 3 hardware procedures using phototherapy, laser non-ablative remodeling and volumetric modeling with hyaluronic acid-based drugs), in group II — 3 hardware procedures with the use of phototherapy and laser non-ablative remodeling, in group III — comprehensive correction (skin preparation by biorevitalizants, 3 hardware procedures using phototherapy and laser non-ablative remodeling), in group IV — 3 hardware procedures with the application of phototherapy, in group V — only volumetric correction.

RESULTS

Improvement of skin color and smoothing of small wrinkles have been observed in all groups, but the most significant reduction of erythema has been noted in groups I and III. Thus, the skin redness has reduced after the biorevitalization procedure before the start of the hardware correction. The depth of wrinkles and folds has expectedly decreased in groups I and V, as well as to a lesser extent in group III. No significant change in skin color has been demonstrated in patients of group V. Patients in all groups have reported improvement on the grading scales as well as high satisfaction level.

CONCLUSION

The study confirms the safety and efficacy of combining biorevitalizants, hardware technologies and hyaluronic acid-based fillers in the comprehensive protocols for rejuvenation and improvement of skin quality. The analysis of the obtained results shows a more pronounced reduction in pigmentation, erythema and wrinkles in patients who underwent complex correction.