Devergie disease or pityriasis rubra pilaris (PRP) — is an idiopathic hyperproliferative dermatosis. Clinically it is characterized by follicular papules, usually disseminated reddish orange scaling plaques with areas of normal skin around; palm and feet keratoderma. Onset occurs in the first or the fifth decade of life. From the five clinical types of PRP, according to Griffiths W.A. Classification (1980), type IV (atypical juvenile) is rare. It develops during the first years of life. PRP is characterized by acquired well-defined plaques of follicular hyperkeratosis located on variably distinguished erythematous areas on knee and elbow joins, less often on other areas of the skin. Sometimes hyperkeratosis or cracks on palms and feet may be present. In some cases, onychodystrophy may be noted. We followed up a five-year-old female patient A. that in 4 years of the disease was diagnosed by different dermatologists with various conditions: Atopic dermatitis, psoriasis, follicular keratosis, xerosis, streptodermia Treatment that followed brought only temporary effect. Biopsy from the lesions was performed in daytime hospital of «Kolomenskiy» branch of State Budgetary Healthcare institution «Moscow Scientific and Practical Center of Dermatovenerology and Cosmetology» of the Healthcare Department of Moscow. Histologically diagnoses of psoriasis and Devergie disease were not excluded. During treatment (2% salicylic ointment, «Topikrem», «Pimafucort», «Losterin») we noted positive trend of skin condition, its stabilization.