Epidemiology of atopic dermatitis

Khamaganova I.V.; Novozhilova O.L.; Vorontsova I.V.

doi:https://doi.org/10.17116/klinderma201716421-25

Close metadata

Recommended articles:

Dynamics of Substance P and Filaggrin Levels on Combined Treatment of Atopic Dermatitis with Emollient and Topical Antipruritic Drug in Pregnant Women. Russian Journal of Clinical Dermatology and Venereology. 2024;(6):662-666

Atopic dermatitis and skin toxic reactions: comparative characteristics, psychosomatic aspects and patient management tactics. Russian Journal of Clinical Dermatology and Venereology. 2024;(6):744-752

Infectious factors in atopic dermatitis, pharmaceutical possibilities (systematic literature review). Russian Journal of Clinical Dermatology and Venereology. 2025;(1):7-15

Retrospective analysis of sexually transmitted infections incidence in countries of the world. Russian Journal of Clinical Dermatology and Venereology. 2025;(2):132-142

Epidemiology of M. genitalium infection. What is known?. Russian Journal of Clinical Dermatology and Venereology. 2025;(2):143-152

Search of diagnostic and prognostic biomarkers of immunoinflammatory dermatoses by means of flow cytometry. Russian Journal of Clinical Dermatology and Venereology. 2025;(2):170-177

Clinical and epidemiological characteristics of myasthenia in the Altai region. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(11):198-202

The results of a 5-year clinical and epidemiological study of the National Program “Chronic tonsillitis”. Russian Bulletin of Otorhinolaryngology. 2024;(6):28-39

Laboratory diagnostics of monkeypox: basic methods and prospects for new developments. Laboratory Service. 2024;(4):57-64

Gastrointestinal stromal tumors of the esophagus in adults: a systematic review. Russian Journal of Evidence-Based Gastroenterology. 2025;(1):5-28

Abstract:

Atopic dermatitis is a common chronic dermatoses, lowering patients’ quality of life. Objective — the study is aimed at analyzing the literature dealing with the epidemiology of atopic dermatitis and investigating the disease in Moscow. Material and methods. The study included available literature data on the epidemiology of atopic dermatitis and the data of the Moscow Research and Practical Center for Dermatology and Cosmetology of the Moscow Department of Health for 2011—2013 years. Results. The analysis of the literature shows further increase in the incidence of atopic dermatitis, multiple comorbidities, and distribution of exogenous and endogenous pathogenic factors. In Moscow, absolute incidence rate of atopic dermatitis decreased during the period from 2011 to 2013. At the same time, its proportion varied from 6.4% in 2013 to 13.4% in 2012. Conclusion. The results of the analysis of published data show the increase in the incidence and spread of atopic dermatitis in different countries. In Moscow, the study of epidemiological situation should be continued.

Keywords:

atopic dermatitis

epidemiology

incidence in Moscow

Authors:

Khamaganova I.V.

Russian State Medical University, Moscow

Novozhilova O.L.

Moskovskiĭ nauchno-prakticheskiĭ tsentr dermatovenerologii i kosmetologii Departamenta zdravookhraneniia Moskvy, 119071, Moskva, Rossiĭskaia Federatsiia

Vorontsova I.V.

Moscow Sientific and Practical Center of Dermatovenereology and Cosmetology, Moscow, Russia, 119071

Close metadata

References:

Baurecht H, Hotze M, Brand S, et al. Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms. Am J Hum Genet. 2015;96(1):104-120. https://doi.org/10.1016/j.ajhg.2015.10.018
Lind N, Nordin M, Palmquist E, et al. Coping and social support in asthma and allergy: the Västerbotten Environmental Health Study. J Asthma. 2014;24:1-8. https://doi.org/10.3109/02770903.2014.991970
Margolis DJ, Gupta J, Apter AJ, et al. Exome sequencing of filaggrin and related genes in African-American children with atopic dermatitis. J Invest Dermatol. 2014;134(8):2272-2274. https://doi.org/10.1038/jid.2014.126
Lytkina EA, Potekaev NN, Bilalova UG, et al. The quality of life of the patients presenting with atopic dermatitis and their compliance with external therapy. Klinicheskaya dermatologiya and venerologia. 2011;1:45-48. (In Russ.).
Chang YS, Chou YT, Lee JH, et al. Atopic dermatitis, melatonin, and sleep disturbance. Pediatrics. 2014;134(2):397-405. https://doi.org/10.1542/peds.2014-0376
Gashimova KhA, Chernikova EA, Kochergin NG. Atopic dermatitis and intestinal parasitoses in the population of the Republic of Dagestan. Klinicheskaya dermatologia and venerologiya. 2009;1:44-48. (In Russ.).
Madhok V, Futamura M, Thomas KS, Barbarot S. What’s new in atopic eczema? An analysis of systematic reviews published in 2012 and 2013. Part 1. Epidemiology, mechanisms of disease and methodological issues. Clin Exp Dermatol. 2015;40(3)238-242. https://doi.org/10.1111/ced.12578
Landis ET, Davis SA, Taheri A, Feldman SR. Top dermatologic diagnoses by age. Dermatol Online J. 2014;20(4):22368.
Pesce G, Marcon A, Carosso A, et al. Adult eczema in Italy: prevalence and associations with environmental factors. J Eur Acad Dermatol Venereol. 2014. https://doi.org/10.1111/jdv.12784
Liebhart J, Dobek R, Małolepszy J, et al.The Prevalence of Allergic Diseases in Poland — the Results of the PMSEAD Study in Relation to Gender Differences. Adv Clin Exp Med. 2014;23(5):757-762. https://doi.org/10.17219/acem/37238
Hwang CY, Chen YJ, Lin MW, et al. Prevalence of atopic dermatitis, allergic rhinitis and asthma in Taiwan: a national study 2000 to 2007. Acta Derm Venereol. 2010;90(6):589-594. https://doi.org/10.2340/00015555-0963
Dhami S, Sheikh A. Estimating the prevalence of aero-allergy and/or food allergy in infants, children and young people with moderate-to-severe atopic eczema/dermatitis in primary care: multi-centre, cross-sectional study. J R Soc Med. 2015. https://doi.org/10.1177/2054270415593443
Kungurov NV, Kokhan MM, Shabardina OV, et al. Analysis of dermatological morbidity from the data of the Urals Research Institute hospital. Rossiskii zhurnal kozhnych i venericheskih boleznei. 2003;6:54-60. (In Russ.).
Khamaganova IV, Trofimchuk IA, Nikiforova GD, et al. The factors of risk and development of allergic dermatoses in children and adolescents (according to the 2002—2006 records of Children’s Infection Hospital Eight). Rossiskii zhurnal kozhnych i venericheskih boleznei. 2008;1:31-34. (In Russ.).
Sybilski AJ, Raciborski F, Lipiec A, et al.Epidemiology of atopic dermatitis in Poland according to the Epidemiology of Allergic Disorders in Poland (ECAP) study. J Dermatol. 2014;42(2):140-147. https://doi.org/10.1111/1346-8138.12731
Leung PS, Shu SA, Chang C. The changing geoepidemiology of food allergies. Clin Rev Allergy Immunol. 2014;46(3):169-179. https://doi.org/10.1007/s12016-014-8411-5
Wang IJ, Karmaus WJ. The effect of phthalate exposure and filaggrin gene variants on atopic dermatitis. Environ Res. 2015;136:213-218. https://doi.org/10.1016/j.envres.2014.09.032
Cipriani F, Dondi A, Ricci G. Recent advances in epidemiology and prevention of atopic eczema. Pediatr Allergy Immunol. 2014 Nov;25(7):630-638. Epub 2014 Dec 10. https://doi.org/10.1111/pai.12309
Gurbanovа MG, Gulordava MD, Chilina GA, et al. Clinical peculiarities of atopic dermatitis complicated by skin mycoses. Probl med mycol. 2012;14:4:43-45. (In Russ.).
Gashimova KhA, Kochergin NG, Chernikova YeA. Impact of concomitant parasitic diseases on the clinical features of atopic dermatitis in Daghestan. Rossiskii zhurnal kozhnych i venericheskih boleznei. 2008;3:32-34. (In Russ.).
Hagel I, Puccio F, López E, et al.Intestinal parasitic infections and atopic dermatitis among Venezuelan Warao Amerindian preschool children. Pediatr Allergy Immunol. 2014;25(3):276-282. https://doi.org/10.1111/pai.12190
Uphoff E, Cabieses B, Pinart M, et al. A systematic review of socioeconomic position in relation to asthma and allergic diseases. Eur Respir J. 2014;46(2):364-374. https://doi.org/10.1183/09031936.00114514
Werner-Busse A, Kostev K, Heine G, Worm M. Impact of comorbidities on the treatment of atopic dermatitis in clinical practice. Int J Clin Pharmacol Ther. 2014;52(9):726-731. https://doi.org/10.5414/cp202040
Chen MH, Su TP, Chen YS, et al. Is atopy in early childhood a risk factor for ADHD and ASD? a longitudinal study. J Psychosom Res. 2014;77(4):316-321. https://doi.org/10.1016/j.jpsychores.2014.06.006
Chen MH, Wu YH, Su TP, et al. Risk of epilepsy among patients with atopic dermatitis: a nationwide longitudinal study. Epilepsia. 2014;55(8):1307-1312. https://doi.org/10.1111/epi.12667
Silverberg JI, Joks R, Durkin HG. Allergic disease is associated with epilepsy in childhood: a US population-based study. Allergy. 2014;69(1):95-103. https://doi.org/10.1111/all.12319
Tsai JD, Lin CL, Shen TC, et al. Increased subsequent risk of myasthenia gravis in children with allergic diseases. J Neuroimmunol. 2014;276(1-2):202-206. https://doi.org/10.1016/j.jneuroim.2014.08.627
Liew WK, Lim CW, Tan TH, et al. The effect of Kawasaki disease on childhood allergies — a sibling control study. Pediatr Allergy Immunol. 2011;22(5):488-493. https://doi.org/10.1111/j.1399-3038.2011.01149.x
Hwang CY, Hwang YY, Chen YJ, et al. Atopic diathesis in patients with Kawasaki disease. J Pediatr. 2013;163(3):811-815. https://doi.org/10.1016/j.jpeds.2013.03.068
Wei CC, Lin CL, Kao CH, et al. Increased risk of Kawasaki disease in children with common allergic diseases. Ann Epidemiol. 2014;24(5):340-343. https://doi.org/10.1016/j.annepidem.2014.02.003
Mathes EF, Oza V, Frieden IJ, et al. «Eczema coxsackium» and unusual cutaneous findings in an enterovirus outbreak. Pediatrics. 2013;132(1):149-157. https://doi.org/10.1542/peds.2012-3175
McCollum AM, Holman RC, Hughes CM, et al. Molluscum contagiosum in a pediatric American Indian population: incidence and risk factors. PLoS One. 2014 Jul 29;9(7):e103419. https://doi.org/ 10.1371/journal.pone.0103419
Seize MB, Ianhez M, Cestari C. A study of the correlation between molluscum contagiosum and atopic dermatitis in children. An Bras Dermatol. 2011;86(4):663-668. https://doi.org/10.1590/s0365-05962011000400006
Huang KP, Mullangi S, Guo Y, Qureshi AA. Autoimmune, atopic, and mental health comorbid conditions associated with alopecia areata in the United States. JAMA Dermatol. 2013;149(7):789-794. https://doi.org/10.1001/jamadermatol.2013.3049
Silverberg JI, Simpson EL. Association between severe eczema in children and multiple comorbid conditions and increased healthcare utilization. Pediatr Allergy Immunol. 2013;24(5):476-486. https://doi.org/10.1111/pai.12095
Lee SL, Lam TH, Leung TH, et al. Foetal exposure to maternal passive smoking is associated with childhood asthma, allergic rhinitis, and eczema. Scientific World Journal. 2012;2012:542983. https://doi.org/10.1100/2012/542983
Tanaka K, Miyake Y, Sasaki S, et al. Osaka maternal and child health study group. Maternal smoking and environmental tobacco smoke exposure and the risk of allergic diseases in Japanese infants: the Osaka Maternal and Child Health Study. J Asthma. 2008;45(9):833-888. https://doi.org/10.1080/02770900802252119
Saulyte J, Regueira C, Montes-Martínez A, et al. Active or passive exposure to tobacco smoking and allergic rhinitis, allergic dermatitis, and food allergy in adults and children: a systematic review and metaanalysis. PLoS Med. 2014 Mar 11;11(3):e1001611. https://doi.org/10.1371/journal.pmed.1001611.eCollection2014
Bjerg A, Rönmark E, Hagstad S. et al. Gas, dust and fume exposure is associated with mite sensitisation and with asthma in mite-sensitised adults. Allergy.2015;70(5):604-607. https://doi.org/10.1111/all.12584
Selissky GD, Izmerova NI, Khamaganova IV, et al.New dermatological syndromes associated with modern potentially pathogenic environmental factors. Klinicheskaya dermatology and venerology. 2011;3:72-77. (In Russ.).
Khamaganova IV, Selisskiĭ GD, Izmerova NI, et al. Occupational skin and respiratory allergoses in hairdressing salons and beauty parlors. Klinicheskaya dermatologia i venerologiya. 2013;2:75-79. (In Russ.).
Azuma K, Uchiyama I, Katoh T, et al. Prevalence and characteristics of chemical intolerance: a Japanese population-based study. Arch Environ Occup Health. 2014;70(6):341-353. https://doi.org/ 10.1080/19338244.2014.926855