Packed red blood cell transfusions in perioperative period in patients with gastrointestinal malignancies

Sazhin A.V.; Kumukova I.B.; Ermakov I.V.; Dalgatov K.D.; Mamedov E.A.

doi:https://doi.org/10.17116/hirurgia202604116

Sazhin A.V.

Pirogov Russian National Research Medical University, Moscow, Russia;
Moscow Multi-Field Clinical Center «Kommunarka», Moscow, Russia

SPIN RSCI: 7064-6369
Scopus AuthorID: 6701753208
ORCID: 0000-0001-6188-6093

Kumukova I.B.

Moscow Multi-Field Clinical Center «Kommunarka», Moscow, Russia

ORCID: 0000-0002-9881-1041

Ermakov I.V.

Pirogov Russian National Research Medical University, Moscow, Russia;
Moscow Multi-Field Clinical Center «Kommunarka», Moscow, Russia

SPIN RSCI: 8154-9166
Scopus AuthorID: 57204167671
ORCID: 0000-0001-9103-6073

Dalgatov K.D.

Pirogov Russian National Research Medical University, Moscow, Russia;
Moscow Multi-Field Clinical Center «Kommunarka», Moscow, Russia

ORCID: 0000-0001-5324-4752

Mamedov E.A.

Pirogov Russian National Research Medical University, Moscow, Russia;
Moscow Multi-Field Clinical Center «Kommunarka», Moscow, Russia

ORCID: 0009-0008-2035-999X

Packed red blood cell transfusions in perioperative period in patients with gastrointestinal malignancies

Authors:

Sazhin A.V., Kumukova I.B., Ermakov I.V., Dalgatov K.D., Mamedov E.A.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2026;(4): 16‑21

DOI: 10.17116/hirurgia202604116

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To cite this article:

Sazhin AV, Kumukova IB, Ermakov IV, Dalgatov KD, Mamedov EA. Packed red blood cell transfusions in perioperative period in patients with gastrointestinal malignancies. Pirogov Russian Journal of Surgery. 2026;(4):16‑21. (In Russ.)
https://doi.org/10.17116/hirurgia202604116

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)

Использование инфографики авторами научных работ

OBJECTIVE

To compare the incidence of postoperative complications in patients with gastrointestinal cancer and anemia depending on red blood cell transfusion.

MATERIAL AND METHODS

We analyzed treatment outcomes in patients with anemia who underwent surgery between 01.01.2022 and 30.01.2024. The main group included 105 patients who received red blood cell transfusions, the control group — 124 patients without transfusions. We assessed postoperative complications according to the Clavien-Dindo classification, length of hospital stay, readmission, 30-day and 90-day mortality.

RESULTS

The study included 229 patients. Transfusions were performed in 105 (45.9%) patients, and there were no transfusions in 124 (54.1%) patients. Postoperative complications were more common in patients with transfusions (26.6% vs. 45.7%, p=0.003) (mainly Clavien-Dindo grade II (15.3% vs. 36.2%, p<0.001) and grade V (0% vs. 7.6%, p=0.002)). In patients with transfusions, hospital stay was 14 days, without transfusion — 11 days (p=0.001). Readmission rate (0% versus 14.3%, p<0.001), 30-day (0% and 6.7%, p=0.004) and 90-day mortality (0% and 11.4%, p<0.001) were higher in the transfusion group.

CONCLUSION

Correction of anemia with red blood cell transfusions in patients with gastrointestinal cancer increases the incidence of postoperative complications, length of hospital stay, readmission rate, 30-day and 90-day mortality.

Keywords:

anemia

perioperative period

red blood cell transfusion

cancer

complications

anastomoses

Authors:

Sazhin A.V.

Pirogov Russian National Research Medical University, Moscow, Russia;
Moscow Multi-Field Clinical Center «Kommunarka», Moscow, Russia

SPIN RSCI: 7064-6369
Scopus AuthorID: 6701753208
ORCID: 0000-0001-6188-6093

Kumukova I.B.

Moscow Multi-Field Clinical Center «Kommunarka», Moscow, Russia

ORCID: 0000-0002-9881-1041

Ermakov I.V.

Pirogov Russian National Research Medical University, Moscow, Russia;
Moscow Multi-Field Clinical Center «Kommunarka», Moscow, Russia

SPIN RSCI: 8154-9166
Scopus AuthorID: 57204167671
ORCID: 0000-0001-9103-6073

Dalgatov K.D.

Pirogov Russian National Research Medical University, Moscow, Russia;
Moscow Multi-Field Clinical Center «Kommunarka», Moscow, Russia

ORCID: 0000-0001-5324-4752

Mamedov E.A.

Pirogov Russian National Research Medical University, Moscow, Russia;
Moscow Multi-Field Clinical Center «Kommunarka», Moscow, Russia

ORCID: 0009-0008-2035-999X

Received:

07.05.2025

Accepted:

15.06.2025

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