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Belov S.A.

Seaside Regional Anti-tuberculosis dispensary

Grigoryuk A.A.

Chair of Operational and Clinical Surgery Vladivostok State Medical University, Vladivostok

Cytokines in surgery for pulmonary tuberculosis

Authors:

Belov S.A., Grigoryuk A.A.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2018;(3): 39‑42

DOI: 10.17116/hirurgia20183239-42

Views: 559

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Table of contents

CYTOKINES IN SURGERY FOR PULMONARY TUBERCULOSIS
CYTOKINES IN SURGERY FOR PULMONARY TUBERCULOSIS

To cite this article:

Belov SA, Grigoryuk AA. Cytokines in surgery for pulmonary tuberculosis. Pirogov Russian Journal of Surgery. 2018;(3):39‑42. (In Russ.)
https://doi.org/10.17116/hirurgia20183239-42

 
Подписка 2025-2 (Pirogov Russian Journal of Surgery)
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Aim. To evaluate the effect of various methods of thoracoplasty on local production of cytokines in patients with pulmonary tuberculosis. Material and methods. The main group consisted of patients after traditional thoracoplasty. Thoracoplasty was compared with endoprosthesis of polypropylene mesh «Surgipro — SPMM-149». TNF-α and IL-10 cytokines in exudate from surgical area were measured by using of solid-phase enzyme immunoassay (OOO «Vector-Best», Russia). Results. It was revealed that local production of pro- and anti-inflammatory cytokines is more pronounced after thoracoplasty with polypropylene mesh «Surgipro — SPMM-149». Local cytokine balance changes towards inflammation were more pronounced after thoracoplasty with mesh implant and did not depend on the degree of drug sensitivity.

Keywords:

cytokines
thoracoplasty
pulmonary tuberculosis

Authors:

Belov S.A.

Seaside Regional Anti-tuberculosis dispensary

Grigoryuk A.A.

Chair of Operational and Clinical Surgery Vladivostok State Medical University, Vladivostok

List of references:

  1. Belov SA, Panchoyan VM, Grigoryuk AA. Patent RF №2496431/27.10.2013. Byul. №30. Sposob khirurgicheskogo lecheniya tuberkuleza legkikh. Accessed March 27, 2017. (In Russ.) http://www.findpatent.ru/patent/249/2496431.html....
  2. Каdyrov АS, Кitaev МI, Dudenko ЕV, Sydykova SS, Тоrtorgazieva КА, Аbdurasulov IА. Сhange in the parameters of the cytokine system during chemotherapy of pulmonary tuberculosis with multidrug-resistant mycobacteria. Nauka, novye tekhnologii i innovatsii. 2016;2:36-38. (In Russ.).
  3. Kravchenko AF. Thoracoplasty influence on the cardiorespiratory and immune systems of patients with tuberculosis. Yakutskii meditsinskii zhurnal. 2013;41:1:73-76. (In Russ.)
  4. Chernushenko EF, Kadan LP, Panasiukova OR, Petishkina NV, Tsigankova LM. Cytokines in the evaluation of the immunity system in patients with lung tuberculosis. Ukrain’skii pul’monologitsnii zhurnal. 2010;2:39-43. (In UA.)
  5. Cardoso de Oliveira LR, Peresi E, De Assis Golim M, Gatto M, Araujo Junior JP, Nunes de Costa EAP, Ayres JA, Fortes MRP, Calvi SA. Analysis of toll-like receptors, inos and cytokine profiles in patients with pulmonary tuberculosis during anti-tuberculosis treatment. Plos one. 2014;9(2):88572. https://doi.org/10.1371/journal.pone.0088572
  6. Tan Q, Xie WP, Min R, Dai GQ, Xu CC, Pan HQ, Miao CD, Yang Z, Xu WG, Wang H. Characterization of Th1-and Th2-type immune response in human multidrug-resistent tuberculosis. European journal of clinical microbiology infectious diseases. 2012;31(6):1233-1242. https://doi.org/10.1007/s10096-011-1434-4

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