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Sheglov E.A.

Petrozavodsk State University, Petrozavodsk, Russia

Alonceva N.N.

Emergence care hospital, Petrozavodsk

Current study aimed to highlight extent of clot resolution in deep veins and its association with anticoagulation pattern in VTE patients

Authors:

Sheglov E.A., Alonceva N.N.

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Journal: Pirogov Russian Journal of Surgery. 2017;(4): 56‑60

DOI: 10.17116/hirurgia2017456-60

Read: 9842 times

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CURRENT STUDY AIMED TO HIGHLIGHT EXTENT OF CLOT RESOLUTION IN DEEP VEINS AND ITS ASSOCIATION WITH ANTICOAGULATION PATTERN IN VTE PATIENTS
CURRENT STUDY AIMED TO HIGHLIGHT EXTENT OF CLOT RESOLUTION IN DEEP VEINS AND ITS ASSOCIATION WITH ANTICOAGULATION PATTERN IN VTE PATIENTS

To cite this article:

Sheglov EA, Alonceva NN. Current study aimed to highlight extent of clot resolution in deep veins and its association with anticoagulation pattern in VTE patients. Pirogov Russian Journal of Surgery. 2017;(4):56‑60. (In Russ.)
https://doi.org/10.17116/hirurgia2017456-60

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)
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Abstract:

Material and Methods. Data of 70 patients with acute VTE of lower extremities (iliofemoral level) was analyzed. There were 42 patients in the study group which were treated with rivaroxaban (15 mg BID for 21 days, 20 mg od from day 22); 28 patients were in control group treated with conventional therapy (LMWH/VKA). Extent of clot resolution was assessed on ultrasound. Data was collected at a day of VTE diagnosis and further at 1, 3, 6 month. Results. The results of the study demonstrated, that patients treated with rivaroxaban had earlier recanalization and extent of clot resolution was higher than in patients treated with conventional therapy. After one year of treatment 73,8% of patients in the study group had total or good recanalization compared to 37% of patients in the control group.

Keywords:

acute deep vein
thrombosis
recanalization
conventional therapy
rivaroxaban
varfarin

Authors:

Sheglov E.A.

Petrozavodsk State University, Petrozavodsk, Russia

Alonceva N.N.

Emergence care hospital, Petrozavodsk

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References:

  1. Russian Clinical Recommendations on Diagnosis, Treatment and Prophylactics of Venous Thromboembolism (VTE). Phlebology. 2015;9(4):2:2-52. (In Russ.).
  2. Avksentyeva MV, Shatalova OV. Pharmacoeconomic Evaluation of Treating Acute Venous Thromboembolism with Rivaroxaban in the Inpatient Setting. Medical Council. 2014;(8):18-23. (In Russ.). doi:10.21518/2079-701X-2014-8-18-23
  3. Prevention and Treatment of Venous Thromboembolism. International Consensus Statement (Guidelines According to Scientific Evidence). International Angiology. 2013;32(2):111-259.
  4. Shevchenko YuL, Stoyko YuM. Fundamentals of Clinical Phlebology. 2nd ed. M.: «Shiko»; 2013. (In Russ.).
  5. Kuznetsov MR, Sapelkin SV, Boldin BV, Leontiev SG, Neskhodimov LA. Recanalization of Lower-Limb Deep Veins as an Index of Efficacy of Treatment for Acute Venous Thrombosis. Angiology and Vascular Surgery. 2016;22(3):82-88. (In Russ.).
  6. Liu D, Peterson E, Dooner J, Baerlocher M, Zypchen L, Gagnon J, Delorme M, Sing CK, Wong J, Guzman R, Greenfield G, Moodley O, Yenson P. Diagnosis and Management of Iliofemoral Deep Vein Thrombosis: Clinical Practice Guideline. CMAJ. 2015;(187):187:1288-1296. Accessed February 02, 2017. Available at: http://www.cmaj.ca/content/187/17.toc doi: 10.1503/cmaj.141614
  7. Kearon C, Akl EA, Ornelas J, Blaivas A, Jimenez D, Bounameaux H, Huisman M, King CS, Morris T, Sood N, Stevens SM, Vintch JRE, Wells P, Woller SC, Moores L. Antithrombotic Therapy for VTE Disease: CHEST Guideline. Chest. 2016;150(4):988-988. doi:10.1016/j.chest.2016.08.1442
  8. Strijkers RHW, Wittens CHA, Kahn SR. Villalta Scale: Goals and Limitations. Phlebology. 2012;27(suppl 1):130-135. doi:10.1258/phleb.2011.012S02
  9. Churikov DA, Kirienko AI. Ultrasound Diagnosis of Vein Diseases. M.: Litterra; 2006. (In Russ.).
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