The definition of sepsis. 25-year experience of concept development

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The review, presented in chronological order the stages of formation of the modern definition of sepsis syndrome, since the recommendations of the conciliation conference ACCP/SCCM (1991), the experience of the practical use of which has been extensively critically assessed in future studies. As a result, it formed a strong opinion that the global challenge of early diagnosis of sepsis, under the previously proposed definitive categories have not been solved, moreover, in the scientific community formed a firm belief in the need to make fundamental changes in the definition of the term «sepsis». As a result, in 2016 the scientific community were presented the recommendations of the working group «Sepsis-3», in which sepsis is defined as life-threatening organ dysfunction due to dysregulated response to infection, and fundamentally distinguish them from the former, is a laconic definitions and availability of diagnostic criteria. National expert community to analyze, discuss and define the field of clinical testing «Sepsis-3» in the Russian Federation.

Keywords:

sepsis

septic shock

definition

Authors:

Sazhin V.P.

Kafedra khirurgii i OVP s kursom éndokhirurgii fakul'teta poslediplomnogo obrazovaniia Rossiĭskogo gosudarstvennogo meditsinskogo universiteta im. akad. I.P. Pavlova, Novomoskovskaia gorodskaia klinicheskaia bol'nitsa

Karsanov A.M.

Department of Hospital surgery, Volgograd State Medical University, Ministry of Health of the Russian Federation

Maskin S.S.

Department of Hospital surgery, Volgograd State Medical University, Ministry of Health of the Russian Federation

Remizov O.V.

FGU Éndokrinologicheskiĭ nauchnyĭ tsentr Minzdravsotsrazvitiia RF

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