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Sazhin V.P.

Kafedra khirurgii i OVP s kursom éndokhirurgii fakul'teta poslediplomnogo obrazovaniia Rossiĭskogo gosudarstvennogo meditsinskogo universiteta im. akad. I.P. Pavlova, Novomoskovskaia gorodskaia klinicheskaia bol'nitsa

Karsanov A.M.

Department of Hospital surgery, Volgograd State Medical University, Ministry of Health of the Russian Federation

Maskin S.S.

Department of Hospital surgery, Volgograd State Medical University, Ministry of Health of the Russian Federation

Remizov O.V.

FGU Éndokrinologicheskiĭ nauchnyĭ tsentr Minzdravsotsrazvitiia RF

The definition of sepsis. 25-year experience of concept development

Authors:

Sazhin V.P., Karsanov A.M., Maskin S.S., Remizov O.V.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2017;(1): 82‑87

Read: 1559 times


To cite this article:

Sazhin VP, Karsanov AM, Maskin SS, Remizov OV. The definition of sepsis. 25-year experience of concept development. Pirogov Russian Journal of Surgery. 2017;(1):82‑87. (In Russ.)
https://doi.org/10.17116/hirurgia2017182-87

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References:

  1. Karsanov AM, Мaskin SS, Slepushkin VD, Karsanova ZO, Derbenzeva TV, Salamova FT, Каraev ТR. Clinical and epidemiological significance of systemic inflammation and sepsis. Vestnik khirurgii. 2015;(4):99-103. (In Russ.).
  2. Larichev AV. Again about sepsis: philosophy of dialectical unity of definition and clinical practice. Khirurgiia. 2015;10:84-87. (In Russ.). doi: 10.17116/hirurgia20151084-87
  3. Мaskin SS, Karsanov AM, Derbenzeva TV, Matiukhin VV, Karsanova ZO. Varied selection of tactical decisions in generalized intra-abdominal infections. Moscovskiy khirurgicheskiy zhurnal. 2015;41(1):36-41. (In Russ.).
  4. Nekhaev IV. Sepsis in the thoraco-abdominal cancer surgery. М.: АВV-press; 2011.
  5. Rudnov VA, Kalabukhov VV. Sepsis and teragnostic. On the way to personalized medicine. Vestnik anesteziologii i reanimatologii. 2015;12(6):60-67.
  6. Saveliev VS, Gelfand BR. Sepsis: classification, clinical and diagnostic concept and treatment. М.: МIA; 2010.
  7. Shlyapnikov SA, Stozharov VV, Zueva LP, Kolosovskaya EN, Fedorova VV, Kechaewa NV, Savina VА. Basic principles on the use of clinical statistical groups for the treatment of severe sepsis. Infektsii v khirurgii. 2015;13(1):3-10.
  8. Angus DC, van der Poll T. Severe sepsis and septic shock. N Engl J Med. 2013;369(9):840-851. doi: 10.1056/NEJMra1208623
  9. Bauer PR, Kashyap R, League SC, Park JG, Block DR, Baumann NA, Algeciras-Schimnich A, Jenkins SM, Smith CY, Gajic O, Abraham RS. Diagnostic accuracy and clinical relevance of an inflammatory biomarker panel for sepsis in adult critically ill patients. Diagn Microbiol Infect Dis. 2016;84(2):175-180. doi: 10.1016/j.diagmicrobio.2015.10.003
  10. Bone RC, Sibbald WJ, Sprung CL. The ACCP-SCCM consensus conference on sepsis and organ failure. Chest. 1992;101(6):1481-1483.
  11. Churpek MM, Zadravecz FJ, Winslow C, Howell MD, Edelson DP. Incidence and prognostic value of the systemic inflammatory response syndrome and organ dysfunctions in ward patients. Am J Respir Crit Care Med. 2015;192(8):958-964. doi: 10.1164/rccm.201502-0275OC
  12. Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM, Nunnally ME, Townsend SR, Reinhart K, Kleinpell RM, Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb SA, Beale RJ, Vincent JL, Moreno R. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med. 2013;41(2):580-637. doi: 10.1097/CCM.0b013e31827e83af
  13. Donnelly JP, Hohmann SF, Wang HE. Unplanned Readmissions After Hospitalization for Severe Sepsis at Academic Medical Center-Affiliated Hospitals. Crit Care Med. 2015;43(9):1916-1927. doi: 10.1097/CCM.0000000000001147
  14. Fleischmann C, Scherag A, Adhikari NK, Hartog CS, Tsaganos T, Schlattmann P, Angus DC, Reinhart K. International Forum of Acute Care Trialists. Assessment of global incidence and mortality of hospital-treated sepsis — current estimates and limitations. Am J Respir Crit Care Med. 2016;193(3):259-272. doi: 10.1164/rccm.201504-0781OC
  15. Gaieski DF, Edwards JM, Kallan MJ, Carr BG. Benchmarking the incidence and mortality of severe sepsis in the United States. Crit Care Med. 2013;41(5):1167-1174. doi: 10.1097/CCM.0b013e31827c09f8
  16. Goodwin AJ, Rice DA, Simpson KN, Ford DW. Frequency, cost, and risk factors of readmissions among severe sepsis survivors. Crit Care Med. 2015;43(4):738-746. doi: 10.1097/CCM.0000000000000859
  17. Horeczko T, Green JP, Panacek EA. Epidemiology of the Systemic Inflammatory Response Syndrome (SIRS) in the Emergency Department. West J Emerg Med. 2014;15(3):329-336. doi: 10.5811/westjem.2013.9.18064
  18. Iwashyna TJ, Govindan S. Did they just prove that a diagnosis of «septic shock» is meaningless? Am J Respir Crit Care Med. 2014;189(10):1156-1157. doi: 10.1164/rccm.201404-0632ED
  19. Kaukonen K-M, Bailey M, Pilcher D, Cooper DJ, Bellomo R. Systemic inflammatory response syndrome criteria in defining severe sepsis. N Engl J Med. 2015;372(17):1629-1638. doi: 10.1056/NEJMoa1415236
  20. Leligdowicz A, Dodek PM, Norena M, Wong H, Kumar A, Kumar A. Association between source of infection and hospital mortality in patients who have septic shock. Am J Respir Crit Care Med. 2014;189(10):1204-1213. doi: 10.1164/rccm.201310-1875OC
  21. Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, Cohen J, Opal SM, Vincent JL, Ramsay G. International Sepsis Definitions Conference. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Intensive Care Med. 2003; 29(4):530-538. doi: 10.1007/s00134-003-1662-x
  22. Liu V, Escobar GJ, Greene JD, Soule J, Whippy A, Angus DC, Iwashyna TJ. Hospital Deaths in Patients With Sepsis From 2 Independent Cohorts. JAMA. 2014;312(1):90-92. doi: 10.1001/jama.2014.5804
  23. Martin GS. Sepsis, severe sepsis and septic shock: changes in incidence, pathogens and outcomes. Expert Rev Anti Infect Ther. 2012;10(6):701-706. doi: 10.1586/eri.12.50
  24. Ortego A, Gaieski DF, Fuchs BD, Jones T, Halpern SD, Small DS, Sante SC, Drumheller B, Christie JD, Mikkelsen ME. Hospital-based acute care use in survivors of septic shock. Crit Care Med. 2015;43(4):729-737. doi: 10.1097/CCM.0000000000000693
  25. Prescott HC. Toward a Nuanced Understanding of the Role of Infection in Readmissions After Sepsis. Crit Care Med. 2016;44(3):634-635. doi: 10.1097/CCM.0000000000001508
  26. Rhee C, Gohil S, Klompas M. Regulatory mandates for sepsis care—reasons for caution. N Engl J Med. 2014;370(18):1673-1676. doi: 10.1056/NEJMp1400276
  27. Rhee C, Kadri SS, Danner RL, Suffredini AF, Massaro AF, Kitch BT, Lee G, Klompas M. Diagnosing sepsis is subjective and highly variable: a survey of intensivists using case vignettes. Crit Care. 2016;20(1):89. doi: 10.1186/s13054-016-1266-9
  28. Shankar-Hari M, Bertolini G, Brunkhorst FM, Bellomo R, Annane D, Deutschman CS, Singer M. Judging quality of current septic shock definitions and criteria. Crit Care. 2015;19(1):445. doi: 10.1186/s13054-015-1164-6
  29. Shankar-Hari M, Deutschman CS, Singer M. Do we need a new definition of sepsis? Intensive Care Med. 2015;41(5):909-911. doi: 10.1007/s00134-015-3680-x
  30. Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, Bellomo R, Bernard GR, Chiche JD, Coopersmith CM,Hotchkiss RS, Levy MM, Marshall JC, Martin GS, Opal SM, Rubenfeld GD, van der Poll T, Vincent J-L, Angus DC. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016;315(8):801-810. doi: 10.1001/jama.2016.0287
  31. Stevenson EK, Rubenstein AR, Radin GT, Wiener RS, Walkey AJ. Two decades of mortality trends among patients with severe sepsis: a comparative meta-analysis. Crit Care Med. 2014;42(3):625-631. doi: 10.1097/CCM.0000000000000026.
  32. Vincent J-L, De Backer D. Circulatory shock. N Engl J Med. 2013;369(18):1726-1734. doi: 10.1056/NEJMra1208943
  33. Vincent J-L, Opal SM, Marshall JC, Tracey KJ. Sepsis definitions: time for change. Lancet. 2013;381(9868):774-775. doi: 10.1016/S0140-6736(12)61815-7
  34. Wang T, Derhovanessian A, De Cruz S, Belperio JA, Deng JC, Hoo GS. Subsequent infections in survivors of sepsis: epidemiology and outcomes. J Intensive Care Med. 2014;29(2):87-95. doi: 10.1177/0885066612467162
  35. Whippy A, Skeath M, Crawford B, Adams C, Marelich G, Alamshahi M, Borbon J. Kaiser Permanente's performance improvement system, part 3: multisite improvements in care for patients with sepsis. Jt Comm J Qual Patient Saf. 2011;37(11):483-493.

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