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Losik D.V.

Scientific group, LLC “MedicBooK”

Nikitin N.A.

Medical Center «Avicenna»

Minin S.M.

Meshalkin National Medical Research Center

Fisher E.V.

V.F. Voino-Yaseneckiy Krasnoyarsk State Medical University

Mikheenko I.L.

Scientific group, LLC “MedicBooK”

Chernyavskiy A.M.

National Medical Research Center

Romanov A.B.

Meshalkin National Medical Research Center

Relationship between epicardial adipose tissue and prognosis of cardiovascular events

Authors:

Losik D.V., Nikitin N.A., Minin S.M., Fisher E.V., Mikheenko I.L., Chernyavskiy A.M., Romanov A.B.

More about the authors

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To cite this article:

Losik DV, Nikitin NA, Minin SM, Fisher EV, Mikheenko IL, Chernyavskiy AM, Romanov AB. Relationship between epicardial adipose tissue and prognosis of cardiovascular events. Russian Journal of Cardiology and Cardiovascular Surgery. 2021;14(4):253‑258. (In Russ.)
https://doi.org/10.17116/kardio202114041253

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References:

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  2. Yi W, Sun Y, Yuan Y, et al. C1q/Tumor Necrosis Factor-Related Protein-3, a Newly Identified Adipokine, Is a Novel Antiapoptotic, Proangiogenic, and Cardioprotective Molecule in the Ischemic Mouse Heart. Circulation. 2012;125:25:3159-3169. https://doi.org/10.1161/CIRCULATIONAHA.112.099937
  3. Uchasova EG, Gruzdeva OV, Dyleva YuA, et al. Epicardial adipose tissue: pathophysiology and role in cardiovascular diseases. Bulletin of Siberian Medicine. 2018;17:4:254-263. (In Russ.). https://doi.org/10.20538/1682-0363-2018-4-254—263
  4. Barber MC, Ward RJ, Richards SE, et al. Ovine adipose tissue monounsaturated fat content is correlated to depot-specific expression of the stearoyl-CoA desaturase gene. J Anim Sci. 2000;78:1:62.  https://doi.org/10.2527/2000.78162x
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  9. Iozzo P. Metabolic toxicity of the heart: insights from molecular imaging. Nutr Metab Cardiovasc Dis. 2010;20;3:147-156.  https://doi.org/10.1016/j.numecd.2009.08.011
  10. Iacobellis G, Bianco AC. Epicardial adipose tissue: emerging physiological, pathophysiological and clinical features. Trends Endocrinol Metab. 2011;22:11:450-457.  https://doi.org/10.1016/j.tem.2011.07.003
  11. Shen MJ, Choi E-K, Tan AY, et al. Neural mechanisms of atrial arrhythmias. Nat Rev Cardiol. 2012;9:1:30-39.  https://doi.org/10.1038/nrcardio.2011.139
  12. Allessie MA, Boyden PA, Camm AJ, et al. Pathophysiology and prevention of atrial fibrillation. Circulation. 2001;103:5:769-777.  https://doi.org/10.1161/01.cir.103.5.769
  13. Minin SM, Nikitin NA, Shabanov V V., et al. Evaluation of CZT SPECT imaging for cardiac sympathetic innervation in healthy individuals and patients with atrial fibrillation. Russ Open Med J. 2018;7:3:e0308. https://doi.org/10.15275/rusomj.2018.0308
  14. Nikitin N, Minin S, Romanov A, et al. Hybrid 123I-mIBG SPECT/CT cardiac imaging for identification of left atrial ganglionated plexi in healthy individuals and patients with atrial fibrillation. Eur Hear J — Cardiovasc Imaging. 2019;20(suppl 3). https://doi.org/10.1093/ehjci/jez150
  15. Soucek F, Covassin N, Singh P, et al. Effects of Atorvastatin (80 mg) Therapy on Quantity of Epicardial Adipose Tissue in Patients Undergoing Pulmonary Vein Isolation for Atrial Fibrillation. Am J Cardiol. 2015;116;9:1443-1446. https://doi.org/10.1016/j.amjcard.2015.07.067
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  17. Romanov A, Pokushalov E, Ponomarev D, et al. Long-term suppression of atrial fibrillation by botulinum toxin injection into epicardial fat pads in patients undergoing cardiac surgery: Three-year follow-up of a randomized study. Hear Rhythm. 2019;16:2:172-177.  https://doi.org/10.1016/j.hrthm.2018.08.01918
  18. Iacobellis G, Gra‐Menendez S. Effects of Dapagliflozin on Epicardial Fat Thickness in Patients with Type 2 Diabetes and Obesity. Obesity. 2020;28:6:1068-1074. https://doi.org/10.1002/oby.22798
  19. Eisenberg E, McElhinney PA, Commandeur F, et al. Deep Learning—Based Quantification of Epicardial Adipose Tissue Volume and Attenuation Predicts Major Adverse Cardiovascular Events in Asymptomatic Subjects. Circ Cardiovasc Imaging. 2020;13:2:e009829. https://doi.org/10.1161/CIRCIMAGING.119.009829
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