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Zolotukhin I.A.

Pirogov Russian National Research Medical University

Arslanbekov M.M.

Pirogov Russian National Research Medical University

Efremova O.I.

Pirogov Russian National Research Medical University

Lebedev I.S.

Pirogov Russian National Research Medical University

Leontiev S.G.

Research Institute of Clinical Surgery of the Pirogov Russian National Research Medical University

Kirienko A.I.

Pirogov Russian National Research Medical University

Validity of Indications for Inferior Vena Cava Filter Placement in Patients with Venous Thromboembolism

Authors:

Zolotukhin I.A., Arslanbekov M.M., Efremova O.I., Lebedev I.S., Leontiev S.G., Kirienko A.I.

More about the authors

Journal: Journal of Venous Disorders. 2021;15(2): 80‑86

DOI: 10.17116/flebo20211502180

Read: 2356 times

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Table of contents

VALIDITY OF INDICATIONS FOR INFERIOR VENA CAVA FILTER PLACEMENT IN PATIENTS WITH VENOUS THROMBOEMBOLISM
VALIDITY OF INDICATIONS FOR INFERIOR VENA CAVA FILTER PLACEMENT IN PATIENTS WITH VENOUS THROMBOEMBOLISM

To cite this article:

Zolotukhin IA, Arslanbekov MM, Efremova OI, Lebedev IS, Leontiev SG, Kirienko AI. Validity of Indications for Inferior Vena Cava Filter Placement in Patients with Venous Thromboembolism. Journal of Venous Disorders. 2021;15(2):80‑86. (In Russ.)
https://doi.org/10.17116/flebo20211502180

Подписка 2026 Флебология (Journal of Venous Disorders)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

OBJECTIVE

To assess the validity of indications for inferior vena cava (IVC) filter placement in patients with venous thromboembolism (VTE).

MATERIAL AND METHODS

A retrospective analysis of a database of patients who underwent IVC filter implantation for VTE was performed. The indications for implantation were analyzed. The control group included patients with IVC filters implanted for absolute indications (impossibility or ineffectiveness of anticoagulation). The study group included patients, who underwent intervention for additional indications, such as non-occlusive proximal deep vein thrombosis (DVT) and/or high pulmonary hypertension. In case of IVC filter occlusion, we determined the most possible genesis (thrombotic or embolic) using the previously developed criteria. IVC filter thrombosis and/or its intactness was considered as unfavorable outcome. The number needed to treat/harm (NNT/NNH) was calculated. The analysis included data on 317 patients. The study protocol is registered at Clinicaltrials.gov (NCT04330170).

RESULTS

IVC filter implantation for impossible anticoagulation was indicated in 41 (12.9%) patients. In 110 (34.7%) cases, IVC filter was implanted due to progressive venous thrombosis despite anticoagulation. Twenty-five (7.9%) patients with pulmonary embolism had pulmonary hypertension grade 2—3. Non-occlusive proximal DVT was observed in 141 (44.5%) patients eligible for IVC filter implantation. Postoperative occlusion of IVC filter was verified in 110 (34.7%) patients. NNH was 18 among patients with non-occlusive proximal DVT. NNT was 6 among patients with high pulmonary hypertension.

CONCLUSION

IVC filter placement in patients with non-occlusive proximal DVT may increase the risk of negative clinical outcome. High pulmonary hypertension with DVT can be considered as an indication for IVC filter implantation.

Keywords:

deep vein thrombosis
venous thromboembolism
inferior cava vena filter
occlusion

Authors:

Zolotukhin I.A.

Pirogov Russian National Research Medical University

Arslanbekov M.M.

Pirogov Russian National Research Medical University

Efremova O.I.

Pirogov Russian National Research Medical University

Lebedev I.S.

Pirogov Russian National Research Medical University

Leontiev S.G.

Research Institute of Clinical Surgery of the Pirogov Russian National Research Medical University

Kirienko A.I.

Pirogov Russian National Research Medical University

Received:

19.02.2021

Accepted:

16.03.2021

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