Quality of Life of Patients with Secondary Lymphedema of the Lower Extremities

Kalinin R.E.

Ryazan State Medical University

ORCID: 0000-0002-0817-9573

Suchkov I.A.

Ryazan State Medical University

SPIN RSCI: 6473-8662
Scopus AuthorID: 56001271800
ResearcherID: M-1180-2016
ORCID: 0000-0002-1292-5452

Maksaev D.A.

Pavlov Ryazan State Medical University

Quality of Life of Patients with Secondary Lymphedema of the Lower Extremities

Authors:

Kalinin R.E., Suchkov I.A., Maksaev D.A.

More about the authors

Journal: Journal of Venous Disorders. 2021;15(1): 6‑12

DOI: 10.17116/flebo2021150116

Downloaded: 80

Download PDF (RU)

Contact the author

Table of contents

To cite this article:

Kalinin RE, Suchkov IA, Maksaev DA. Quality of Life of Patients with Secondary Lymphedema of the Lower Extremities. Journal of Venous Disorders. 2021;15(1):6‑12. (In Russ.)
https://doi.org/10.17116/flebo2021150116

Подписка 2025-2 (Journal of Venous Disorders)

Close metadata

OBJECTIVE

To study the quality of life (QoL) in patients with secondary lymphedema of the lower extremities after different treatment strategies.

MATERIAL AND METHODS

The study included 90 patients aged 31-85 years who were divided into 3 groups of 30 patients each. QoL was assessed using SF-36 questionnaire. The 1^st and 2^nd groups consisted of patients with stage II secondary lymphedema of the lower extremities. In the 1^st group, venoactive drug and compression therapy were administered. Compression therapy alone was applied in the 2^nd group. The 3^rd group (control) included people without venous and lymphatic diseases. QoL was evaluated before treatment and 3 months later using SF-36 questionnaire.

RESULTS

Patients with secondary lymphedema of the lower extremities presented with significantly less scores of physical functioning (PF), role physical functioning (RP), bodily pain (BP), general health (GH), vitality (VT) and mental health (MH) compared to healthy volunteers. Combination of venoactive drug and compression therapy had a significant advantage over elastic compression alone regarding 6 SF-36 scales. The use of elastic compression alone did not significantly improve QoL.

CONCLUSION

Patients with lower limb lymphedema have a lower quality of life in comparison with healthy volunteers. Combination of venoactive drug and compression therapy significantly improved quality of life in patients with secondary lymphedema according to SF-36 questionnaire.

Keywords:

lower limb lymphedema

quality of life

SF-36

venoactive drugs

Authors:

Kalinin R.E.

Ryazan State Medical University

ORCID: 0000-0002-0817-9573

Suchkov I.A.

Ryazan State Medical University

SPIN RSCI: 6473-8662
Scopus AuthorID: 56001271800
ResearcherID: M-1180-2016
ORCID: 0000-0002-1292-5452

Maksaev D.A.

Pavlov Ryazan State Medical University

Received:

02.06.2020

Accepted:

16.07.2020

List of references:

Grada AA, Phillips TJ. Lymphedema: Pathophysiology and clinical manifestations. J Am Acad Dermatol. 2017;77(6):1009-1020. https://doi.org/10.1016/j.jaad.2017.03.022
Fionik OV, Bubnova NA, Petrov SV, Erofeev NP, Ladozhskaya-Gapeenko EE, Semenov AYu. Limfedema nizhnikh konechnostej: algoritm diagnostiki i lecheniya. Novosti khirurgii. 2009;17(4):49-64. (In Russ).
Kalinin RE, Suchkov IA, Maksaev DA. Endothelial dysfunction in patients with secondary lymphedema and methods of its correction (literature review). Science of the Young (Eruditio Juvenium). 2019;7(2):283-93. (In Russ.). https://doi.org/10.23888/HMJ201972283-293
Badtieva VA, Trukhacheva NV, Savin EA. The modern trends in the treatment and prevention of lymphedema of the lower extremities. Problems of Balneology, Physiotherapy, and Exercise Therapy. 2018;95(4):54-61. (In Russ.). https://doi.org/10.17116/kurort20189504154
Stolldorf DP, Dietrich MS, Ridner SH. A Comparison of the Quality of Life in Patients With Primary and Secondary Lower Limb Lymphedema: A Mixed-Methods Study. West J Nurs Res. 2016;38(10):1313-1334. https://doi.org/10.1177/0193945916647961
Huggenberger K, Wagner S, Lehmann S, Aeschlimann A, Amann-Vesti B, Angst F. Health and quality of life in patients with primary and secondary lymphedema of the lower extremity. Vasa. 2015;44(2):129-137. https://doi.org/10.1024/0301-1526/a000419
Issledovanie kachestva zhizni v meditsine. Shevchenko YuL, ed. M.: GEOTAR- Media; 2004.
Müller M, Klingberg K, Wertli MM, Carreira H. Manual lymphatic drainage and quality of life in patients with lymphoedema and mixed oedema: a systematic review of randomised controlled trials. Qual Life Res. 2018; 27(6):1403-1414. https://doi.org/10.1007/s11136-018-1796-5
World Health Organization. The World Health Organization Quality of Life assessment (WHOQOL): position paper from the World Health Organization. Soc Sci Med. 2005;41(10):1403-1409.
Agapov AB. Quality of life assessment using a questionnaires in patients with venous disease of lower extremities. I.P. Pavlov Russian Medical Biological Herald. 2015;3:126-133. (In Russ.).
Amirdjanova VN, Goryachev DV, Korshunov NI, Rebrov AP, Sorotskaya VN. SF-36 questionnaire population quality of life indices Objective. Rheumatology Science and Practice. 2008;46(1):36-48. (In Russ.). https://doi.org/10.14412/1995-4484-2008-852
Herberger K, Blome C, Heyer K, Ellis F, Münter KC, Augustin M. Quality of life in patients with primary and secondary lymphedema in the community. Wound Repair Regen. 2017;25(3):466-473. https://doi.org/10.1111/wrr.12529
Kolinko AN, Nimaev VV, Tupikova EA, Kochetkova MV, Kombantsev EA. Otsenka kachestva zhizni u bol’nykh s vtorichnoj limfedemoj verkhnikh konechnostej. Fundamental’nye issledovaniya. 2008;1:107-108. (In Russ.).
Hoffner M, Bagheri S, Hansson E, Manjer J, Troëng T, Brorson H. SF-36 Shows Increased Quality of Life Following Complete Reduction of Postmastectomy Lymphedema with Liposuction. Lymphat Res Biol. 2017;15(1):87-98. https://doi.org/10.1089/lrb.2016.0035
Pecking AP. Evaluation by lymphoscintigraphy of the effect of a micronized flavonoid fraction (Daflon 500 mg) in the treatment of upper limb lymphedema. Int Angiol. 1995;14(3 Suppl 1):39-43.

Close metadata