Aim — to compare the effectiveness of radiofrequency ablation (RFA) of the great saphenous vein (GSV) in accordance with the standard protocol recommended by the manufacturer with that of the procedure using several heating cycles. Material and methods. 65 patients with primary varicose veins and GSV incompetence were included in the study. The patients were divided into two groups. RFA in patients of the first group has been performed following the standard protocol (n=12). In the second group, radiofrequency ablation was performed taking into consideration changes in the power needed to create effective temperature on the working part of the catheter (n=53). In this group several ablation cycles were used. To compare groups we used a mean sum of postoperative scores for pain and pigmentation assessed by visual-analog scale (VAS) at 7 days after procedure, venous clinical severity score (VCSS) and malleolar perimeter at 6 months. Results. All the RFA procedures led to ablation of GSV trunk. In the second group, pain and pigmentation after the procedure were significantly less and the reduction of obliterated vein diameter required a shorter time to be achieved. The mean sum of postoperative scores for pain and pigmentation assessed by visual-analog scale the day after RFA was the same (16.84±2.85 vs 16.11±2.90; p>0.05). After 7 days, the mean sum was significantly lower in the second group (15.15±3.41 vs 5.03±2.40; p<0.05). The VCSS scale and the malleolar perimeter in both groups significantly decreased 6 months after the RFA. There were no differences between the groups as regards these parameters. Conclusion. RFA performed with several heating cycles is an effective and safe tool for GSV ablation.