BACKGROUND

Roux-en-Y gastric bypass surgery accounts for about 45% of all bariatric interventions. One anastomosis (mini) gastric bypass (MGB) has been developed as an alternative to Roux-en-Y gastric bypass.

OBJECTIVE

The aim of this study was to assess the morphofunctional state of the gastric pouch mucosa after MGB and Roux-en-Y gastric bypass (RYGB) using the biliary reflux index (BRI).

MATERIAL AND METHODS

In the present study, we included the results of a comparative analysis of surgical treatment of 121 patients. The study structure consisted of 58 patients who underwent MGB and 63 patients who underwent RYGB. In the long-term postoperative period, all patients were assessed for signs of reflux using gastroscopy with biopsy and microscopy of biopsy materials. This study is registered with ClinicalTrials.gov, number NCT04845438.

RESULTS

The follow-up period for patients ranged from 36 to 64 months, the average duration of the observation period was 42.6±4.5 months. Analysis of the results according to the Gastroesophageal Reflux Disease-Health-Related Quality of Life questionnaire showed that the severity of symptoms of gastroesophageal reflux disease and their impact on quality of life differed statistically significantly between the study groups. Signs of active gastritis of the gastric stump were observed in 19% of cases in the RYGB group and in 44.8% of cases in the MGB group (p<0.05). In the RYGB group, BRI >14 points was determined in 3 (4.8%) patients; in the MGB group, BRI >14 points was determined in 20.7% of patients. The number of patients with BRI >14 points was statistically significantly (p<0.05) higher in the MGB group.

CONCLUSION

Based on the data obtained, we recommend MGB as an effective method of bariatric surgery with. However, such patients need constant monitoring due to the high risk of developing reflux-associated.