Introduction. Performing a fully laparoscopic intestinal anastomosis remains a challenge for pediatric surgeons. The purpose. Demonstration of this possibility in patients with atresia of the small intestine. Material and methods. The study describes the experience of laparoscopic treatment of 3 patients with atresia of the small intestine of types I and IIIa. In total there were 2 boys and 1 girl. The body weight of patients in the range of 1160—2200 g. During laparoscopy, sutures were placed on the blind end of the atreased intestine, which were then transdermally brought out. In 2 patients, Louw anastomosis was performed, in one — membraneectomy. The early and long-term results of laparoscopic operations were studied. Results. Laparoscopic treatment for atresia of the small intestine was used in 3 patients. One patient had type IIIa atresia of the small intestine (separation of segments with a V-shaped defect of the mesentery), two others had type I (membranous form) of this anomaly. Laparoscopic treatment for all patients was performed on the 2nd day of life. The duration of the operation ranged from 60 to 75 minutes. Enteral nutrition was started after a decrease in the rate of loss with a gastric tube of less than 10 ml/kg/day. This occurred in the range from 3 to 5 days after surgery. A gradual increase in the volume of feeding led to the fact that patients switched to full enteral nutrition 7, 8 and 12 days after surgery. In the early period of observations after surgery, there were no signs of insolvency of the anastomosis. During the observation of patients for 3 months to 2 years, there were no signs of impaired intestinal transit. All infants at the end of the study were able to ingest their own food by mouth and showed normal rates of weight gain and body length. Conclusion. Treatment for atresia of the small intestine has taken a significant step forward. Laparoscopic treatment of such patients by constructing an anastomosis or resection of the membrane became not only possible, but also demonstrated its effectiveness and safety.