Multicentral study of thoracoscopic treatment of congenital diaphragmatic hernia

Kozlov Yu.A.; Kovalkov K.A.; Tshubko D.M.; Rasputin A.A.; Veber I.N.; Baradieva P.Zh.; Timofeev A.D.; Zvonkov D.A.

doi:https://doi.org/10.17116/endoskop20182405110

Kozlov Yu.A.

Gorodskaia Ivano-Matreninskaia detskaia klinicheskaia bol'nitsa, Irkutsk;
Irkutskaia gosudarstvennaia meditsinskaia akademiia poslediplomnogo obrazovaniia

ORCID: 0000-0003-2313-897X

Kovalkov K.A.

Irkutsk State Medical University Pediatric city clinical hospital, Kemerovo

Tshubko D.M.

Regional pediatric clinical hospital, Krasnoyarsk

Rasputin A.A.

Gorodskaia Ivano-Matreninskaia detskaia klinicheskaia bol'nitsa, Irkutsk;
Irkutskiĭ gosudarstvennyĭ meditsinskiĭ universitet;
Irkutskaia gosudarstvennaia meditsinskaia akademiia poslediplomnogo obrazovaniia

Veber I.N.

Irkutsk Municipal Pediatric Clinical Hospital, Irkutsk

Baradieva P.Zh.

Irkutsk State Medical University, Irkutsk, Russia

Timofeev A.D.

Irkutsk Municipal Pediatric Clinical Hospital, Irkutsk, center of surgery and intensive care of the newborns, Irkutsk, Russia;
Irkutsk State Medical University, Irkutsk, Russia

Zvonkov D.A.

Irkutsk State Medical University, Irkutsk, Russia

Multicentral study of thoracoscopic treatment of congenital diaphragmatic hernia

Authors:

Kozlov Yu.A., Kovalkov K.A., Tshubko D.M., Rasputin A.A., Veber I.N., Baradieva P.Zh., Timofeev A.D., Zvonkov D.A.

More about the authors

Journal: Endoscopic Surgery. 2018;24(5): 10‑18

DOI: 10.17116/endoskop20182405110

Read: 1489 times

Download PDF (RU)

Contact the author

Table of contents

To cite this article:

Kozlov YuA, Kovalkov KA, Tshubko DM, et al. Multicentral study of thoracoscopic treatment of congenital diaphragmatic hernia. Endoscopic Surgery. 2018;24(5):10‑18. (In Russ.)
https://doi.org/10.17116/endoskop20182405110

Подписка 2026 Эндоскопическая хирургия (Endoscopic Surgery)

Использование инфографики авторами научных работ

Close metadata

Recommended articles:

Robot-assisted and thoracoscopic operations for esophageal cysts. Case series. Endoscopic Surgery. 2026;(3):27-31

Surgical treatment of posthemorrhagic hydrocephalus in premature infants. Burdenko's Journal of Neurosurgery. 2025;(4):7-17

Predictors of mortality in neonatal spontaneous gastric perforation: a multiple-center study. Pirogov Russian Journal of Surgery. 2025;(9):44-53

External validation of the ETVSS scale for predicting the outcomes after third ventriculostomy in children less than one year of age with obstructive hydrocephalus. Burdenko's Journal of Neurosurgery. 2025;(5):45-53

Hereditary angioedema and pregnancy. Clinical experience. Russian Bulletin of Obstetrician-Gynecologist. 2025;(6):77-82

Thoracoscopic box lesion using non-irrigated bipolar clamp only. Pirogov Russian Journal of Surgery. 2025;(12):33-40

Combined gunshot penetrating chest wounds: current state of the problem (scoping review). Pirogov Russian Journal of Surgery. 2026;(3):78-94

Optimal anesthetic technique for thoracoscopic radiofrequency epicardial ablation of the left atrium. Russian Journal of Anesthesiology and Reanimatology. 2026;(2):59-68

Catamnesis of patients who underwent surgical treatment of placental regrowth in the Russian Federation (pilot multicenter study). Russian Bulletin of Obstetrician-Gynecologist. 2026;(2):5-19

Predictors of outcomes after intensive care for congenital malformations in early neonatal period. Russian Journal of Anesthesiology and Reanimatology. 2026;(3):35-42

Abstract:

In the article we analyze the 15 year experience (2002—2017) of 197 patients with congenital diaphragmatic hernia (CDH) treatment in three children’s hospitals located in Siberian Federal District. Material and methods. Patients were distributed in two groups: group 1 — 90 patients who has got surgical repair of CDH through thoracoscopic approach; group 2 — 107 patients who has got surgical repair of CDH through thoracotomy or laparotomy. The surgical repair procedure of CDH and the recommendation of postoperative maintaining such patients proceeding and controlled by observers from (Ivano-Matreninsky children’s clinical hospital Irkutsk (expert hospital — EG) are applied to patients. Results. The compared groups were similar in terms of demographics parameters. There was significant difference in mean operative time between open and thoracoscopic procedure (64.18 min vs 73.92 min; p<0.05). Duration of care in neonatal intensive unit and length of hospital stay were significantly shorter in the Group 1 (8.82 vs 12.5 days; 19.27 vs 26.46 days; p<0.05). Synthetic patches for repair were used in 21 (23.33%) patients of group 1 and in 14 (13.08%) patients of group 2. Diaphragmatic hernia recurrences were found in 10 (11.11%) patients of group 1 and in 20 (18.69%) patients of group 2. Chylotorax in our research was found in 23 (25.56%) patients of endosurgery group and in 24 (22.42%) patients of open repair group. The lethal outcomes in group 1 were lower than in group 2 (8.89% vs 17.76%). The Nissen fundoplication was performed at 14 (15.56%) babies of group 1 (thoracoscopy) and 10 (9.35%) patients of group 2 (open treatment). Conclusion. Thoracoscopic reconstruction of congenital diaphragmatic hernia can be safely performed by experienced endoscopic surgeons from different centers united by one ideology of performing endosurgical operations.

Keywords:

thoracoscopy

congenital diaphragmatic hernia

neonates

multi-institutional study

thoracoscopy

congenital diaphragmatic hernia

neonates

multi-institutional study

Authors:

Kozlov Yu.A.

Gorodskaia Ivano-Matreninskaia detskaia klinicheskaia bol'nitsa, Irkutsk;
Irkutskaia gosudarstvennaia meditsinskaia akademiia poslediplomnogo obrazovaniia

ORCID: 0000-0003-2313-897X

Kovalkov K.A.

Irkutsk State Medical University Pediatric city clinical hospital, Kemerovo

Tshubko D.M.

Regional pediatric clinical hospital, Krasnoyarsk

Rasputin A.A.

Veber I.N.

Irkutsk Municipal Pediatric Clinical Hospital, Irkutsk

Baradieva P.Zh.

Irkutsk State Medical University, Irkutsk, Russia

Timofeev A.D.

Irkutsk Municipal Pediatric Clinical Hospital, Irkutsk, center of surgery and intensive care of the newborns, Irkutsk, Russia;
Irkutsk State Medical University, Irkutsk, Russia

Zvonkov D.A.

Irkutsk State Medical University, Irkutsk, Russia

Close metadata

References:

The International Centre on Birth Defects. International Clearinghouse for Birth Defects Surveillance and Research Annual Report 2013. ICBDSR Centre. 2013;216.
Tsao K, Lally PA, Lally KP, Congenital Diaphragmatic Hernia Study Group. Minimally invasive repair of congenital diaphragmatic hernia. J Pediatr Surg. 2011;46:1158-1164.
Kozlov YuA, Novozhilov VA, Alejnikova NG, Kuznetsova SN, Kononenko MI, Weber IN, Soloviev AA. Torakoskopicheskaja frenoplikacija u novorozhdennyh (soobshhenieo 3 sluchajah dannoj patologii). Detskaja hirurgija. 2008;1:52-53. (In Russ.)
Kozlov YuA, Novozhilov VA, Podkamenev AV, Yurkov PS, Aleynikova NG, Weber IN, Kononenko MI, Kuznetsova SN, Soloviev AA, Novopashin AM. Torakoskopicheskaja rekonstrukcija vrozhdennoj diafragmal’noj gryzhi Bogdaleka. Detskaja hirurgija. 2009;5:22-24. (In Russ.)
Mitupov ZB, Razumovskij AYu. Jendohirurgicheskie operacii pri diafragmal’nyh gryzhah u detej. Detskaja hirurgija. 2009;3:46-49. (In Russ.)
Razumovskij AYu, Mokrushina OG, Shumihin VS, Afukov II, Smirnova SV. Jendohirurgicheskie operacii na diafragme u novorozhdennyh: pervyjopyt v Rossii. Rossijskij vestnik detskojh irurgii, anesteziologii i reanimatologii. 2012;1:80-86. (In Russ.)
Kozlov YuA, Novozhilov VA, Kovalkov KA, Chubko DM, Rasputin AA, Tysyachny AS, Baradiyeva PA, Us GP, Kuznetsova NN. Endosurgical treatment of diseases of diaphragm at neonates and infants. Endoscopic surgery. 2015;21:25-32. (In Russ.)
Arca MJ, Barnhart DC, LelliJl Jr, Greenfeld J, Harmon CM, Hirschl RB, Teitelbaum DH. Early experience with minimally invasive repair of congenital diaphragmatic hernias: Results and lessons learned. J Pediatr Surg. 2003;38:1563-1568.
Costerus S, Zahn K, van de Ven K, Vlot J, Wessel L, Wijnen R. Thoracoscopic versus open repair of CDH in cardiovascular stable neonates. Surg Endosc. 2016;30:2818-2824.
Tyson A, Sola R, Arnold M, Cosper G, Schulman A. Thoracoscopic versus open congenital diaphragmatic hernia repair: single tertiary center review. Journal of Laparoendoscopic & Advanced Surgical Techniques. 2017;27:1-8.
Snoek K, Kraemer U, Ten Kate C, Greenough A, van Heijst A, Capolupo I, Schaible T, van Rosmalen J, Wijnen R, Reiss I, Tibboel D. High-sensitivity troponin and terminal pro-brain natriuretic peptide in prediction of outcome in congenital diaphragmatic hernia: results from a multicenter, randomized controlled trial. J Pediatr. 2016;173:245-249.
Bishay M, Giacomello L, Retrosi G, Thyoka M, Garriboli M, Brierley J, Harding L, Scuplak S, Cross K, Curry J, Kiely E, De Coppi P, Eaton S, Pierro A. Hypercapnia and acidosis during open and thoracoscopic repair of congenital diaphragmatic hernia and esophageal atresia: results of a pilot randomized controlled trial. Ann Surg. 2013;258:895-900.
Lally PA, Skarsgard ED. Congenital diaphragmatic hernia: The role of multi-institutional collaboration and patient registries in supporting best practice. Semin Pediatr Surg. 2017;26:129-135.
Deeney S, Howley L, Hodges M, Liechty K, Marwan A, Gien J, Kinsella J, Crombleholme T. Impact of Objective Echocardiographic Criteria for Timing of Congenital Diaphragmatic Hernia Repair. J Pediatr. 2018;192:99-104.
Gourlay DM, Cassidy LD, Sato TT, Lal DR, Arca MJ. Beyond feasibility: A comparision of newborns undergoing thoracoscopic and open repair of congenital diaphragmatic hernias. J Pediatr Surg. 2009;44:1702-1707.
Gomes Ferreira C, Reinberg O, Becmeur F, Allal H, D Lagausie P, Lardy H, Philippe P, Lopez M, Varlet F, Podevin G, Schleff J, Schlobach M. Neonatal minimally invasive surgery for congenital diaphragmatic hernias: A multicenter study using thoracoscopy or laparoscopy. Surg Endosc. 2009;23:1650-1659.
Kalfa N, Allal H, Raux O, Lopez M, Forgues D, Guibal MP, Picaud JC, Galifer RB. Tolerance of laparoscopy and thoracoscopy in neonates. Pediatrics. 2005;116:785-791.
Stratmann G, May LD, Sall JW, Alvi RS, Bell JS, Ormerod BK, Rau V, Hilton JF, Dai R, Lee MT, Visrodia KH, Ku B, Zusmer EJ, Guggenheim J, Firouzian A. Effect of hypercarbia and isoflurane on brain cell death and neurocognitive dysfunction in 7-day-old rats. Anesthesiology. 2009;110:849-861.
Bishay M, Giacomello L, Retrosi G, Thyoka M, Nah SA, McHoney M, De Coppi P, Brierley J, Scuplak S, Kiely EM, Curry JI, Drake DP, Cross KM, Eaton S, Pierro A. Decreased cerebral oxygen saturation during thoracoscopic repair of congenital diaphragmatic hernia and esophageal atresia in infants. Journal of Pediatric Surgery. 2011;46:47-51.
Fishman JR, Blackburn SC, Jones NJ, Madden N, De Caluwe D, Haddad MJ, Clarke SA. Does thoracoscopic congenital diaphragmatic hernia repair cause a significant intraoperative acidosis when compared to an open abdominal approach? J Pediatric Surgery. 2011;46:458-461.
Bliss D, Matar M, Krishnaswami S. Should intraoperative hypercapnea or hypercarbia raise concern in neonates undergoing thoracoscopic repair of diaphragmatic hernia of Bochdalek? J Laparoendosc Adv Surg Tech. 2009;19(suppl 1):55-58.
Liem NT, Dien TM, Ung NQ. Thoracoscopic repair in the neonatal intensive care unit for congenital diaphragmatic hernia during high-frequency oscillatory ventilation. J Laparoendosc Adv Surg Tech A. 2010;20:111-114.
Yang EY, Allmendinger N, Johnson SM, Chen C, Wilson JM, Fishman SJ. Neonatal thoracoscopic repair of congenital diaphragmatic hernia: Selection criteria for successful outcome. J Pediatr Surg. 2005;40:1369-1375.
Becmeur F, Reinberg O, Dimitriu C, Moog R, Philippe P. Thoracoscopic repair of congenital diaphragmatic hernia in children. Semin Pediatr Surg. 2007;16:238-244.
Cho SD, Krishnaswami S, Mckee JC, Zallen G, Silen ML, Bliss DW. Analysis of 29 consecutive thoracoscopic repairs of congenital diaphragmatic hernia in neonates compared to historical controls. J Pediatr Surg. 2009;44:80-86.
Kim AC, Bryner BS, Akay B, Geiger JD, Hirschl RB, Mychaliska GB. Thoracoscopic repair of congenital diaphragmatic hernia in neonates: Lessons learned. J Laparoendosc Adv Surg Tech A. 2009;19:575-580.
Szavay PO, Drews K, Fuchs J. Thoracoscopic repair of a right-sided congenital diaphragmatic hernia. Surg Laparos Endosc Percutan Tech. 2005;15:305-307.
Smirnova SV, Razumovskij AYu, Mokrushina OG. Sovremennye sposoby korrekcii vrozhdennyh diafragmal’nyh gryzh u novorozhdennyh. Voprosy prakticheskoj pediatrii. 2012;7:30-34. (In Russ.)
Liem NT, Dung LA. Thoracoscopic repair for congenital diaphragmatic hernia: Lessons from 45 cases. J Pediatr Surg. 2006;41:1713-1715.
Sola JE, Bronson SN, Cheung MC, Ordonez B, Neville HL, Koniaris LG. Survival disparities in newborns with congenital diaphragmatic hernia: a national perspective. J Pediatr Surg. 2010;45:1336-1342.
Grushka JR, Laberge JM, Puligandla P, Skarsgard ED, Canadian Pediatric Surgery Network. Effect of hospital case volume on outcome in congenital diaphragmatic hernia: the experience of the Canadian Pediatric Surgery Network. J Pediatr Surg. 2009;44:873-876.