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Vasil'ev N.V.

FGBNU "Tomskiĭ NII onkologii", Tomsk, Rossiia, 634028

Poletaeva S.V.

GBUZ «Samarskiĭ oblastnoĭ klinicheskiĭ onkologicheskiĭ dispanser»

Maltseva S.A.

Siberian State Medical University, Tomsk, Russia

Zheravin A.А.

E.N. Meshalkin Novosibirsk Research Institute of Blood Circulation Pathology, Novosibirsk, Russia

Tyukalov Yu.I.

Tomsk National Research Medical Center, Tomsk, Russia

Baidala P.G.

Siberian State Medical University, Tomsk, Russia

Extraskeletal osteosarcoma: nosologocal diversity, morphology, differential diagnosis, and features of metastasis

Authors:

Vasil'ev N.V., Poletaeva S.V., Maltseva S.A., Zheravin A.А., Tyukalov Yu.I., Baidala P.G.

More about the authors

Journal: Russian Journal of Archive of Pathology. 2018;80(3): 59‑64

DOI: 10.17116/patol201880359-65

Read: 3775 times

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Table of contents

EXTRASKELETAL OSTEOSARCOMA: NOSOLOGOCAL DIVERSITY, MORPHOLOGY, DIFFERENTIAL DIAGNOSIS, AND FEATURES OF METASTASIS
EXTRASKELETAL OSTEOSARCOMA: NOSOLOGOCAL DIVERSITY, MORPHOLOGY, DIFFERENTIAL DIAGNOSIS, AND FEATURES OF METASTASIS

To cite this article:

Vasil'ev NV, Poletaeva SV, Maltseva SA, Zheravin AА, Tyukalov YuI, Baidala PG. Extraskeletal osteosarcoma: nosologocal diversity, morphology, differential diagnosis, and features of metastasis. Russian Journal of Archive of Pathology. 2018;80(3):59‑64. (In Russ.)
https://doi.org/10.17116/patol201880359-65

Подписка 2026 Архив патологии (Russian Journal of Archive of Pathology)
МСФ на ЯМ
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Abstract:

Extraskeletal osteosarcoma is a rare malignant tumor with histologic similarities to primary bone osteosarcoma. However, there are distinct differences in epidemiology, imaging features, biological characteristics, prognosis, and management compared with osteogenic osteosarcoma. Extraskeletal osteosarcoma is usually characterized as high-grade neoplasm with clinically aggressive behavior, poor prognosis, frequent recurrence/lymphogenic metastatsis, and resistence to chemotherapy. A noteworthy feature of extraskeletal osteosarcoma is the fact that almost all existing biological phenomena described in mesenchymal oncopathology (except primary-multiple lesions) are present in this tumor, namely: secondary malignancy, association with syndromes, partial spontaneous regression of the tumor, dedifferentiation, bone invasion, biphasic pathology. In this paper, we have discussed in detail the tumor morphology, histological subtypes, prognostic factors and differential diagnosis.

Keywords:

extraskeletal osteosarcoma
metastasis
subtype
immunohistochemistry
prognosis

Authors:

Vasil'ev N.V.

FGBNU "Tomskiĭ NII onkologii", Tomsk, Rossiia, 634028

Poletaeva S.V.

GBUZ «Samarskiĭ oblastnoĭ klinicheskiĭ onkologicheskiĭ dispanser»

Maltseva S.A.

Siberian State Medical University, Tomsk, Russia

Zheravin A.А.

E.N. Meshalkin Novosibirsk Research Institute of Blood Circulation Pathology, Novosibirsk, Russia

Tyukalov Yu.I.

Tomsk National Research Medical Center, Tomsk, Russia

Baidala P.G.

Siberian State Medical University, Tomsk, Russia

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