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Chumachenko P.V.

Laboratoriia patomorfologii serdechno-sosudistykh zabolevaniĭ

Afanasyev M.A.

Russian Cardiology Research and Production Complex, Ministry of Health of the Russian Federation, Moscow, Russia

Galankina I.E.

Nauchno-issledovatel'skiĭ institut skoroĭ pomoshchi im. N.V. Sklifosovskogo, Moskva

Ilyina L.N.

Russian Cardiology Research and Production Complex, Ministry of Health of the Russian Federation, Moscow, Russia

Postnov A.Yu.

Institute of the Clinical Cardiology named after A.L. Myasnikov of National Medical Research Center for Cardiology, Moscow, Russia

Gigantic aneurysm of the coronary artery

Authors:

Chumachenko P.V., Afanasyev M.A., Galankina I.E., Ilyina L.N., Postnov A.Yu.

More about the authors

Journal: Russian Journal of Archive of Pathology. 2017;79(5): 21‑24

DOI: 10.17116/patol201779521-24

Views: 3004

Downloaded: 105

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To cite this article:

Chumachenko PV, Afanasyev MA, Galankina IE, Ilyina LN, Postnov AYu. Gigantic aneurysm of the coronary artery. Russian Journal of Archive of Pathology. 2017;79(5):21‑24. (In Russ.)
https://doi.org/10.17116/patol201779521-24

Подписка 2025 (Russian Journal of Archive of Pathology)
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The paper describes a clinical case of gigantic aneurysm of one of the coronary arteries. It considers the morphological and immunohistochemical characteristics of the wall of the blood vessel with the detected signs of coronaritis. The authors have determined that Kawasaki disease could be retrospectively diagnosed in early childhood.

Keywords:

coronary artery aneurysm
Kawasaki disease/syndrome
immunohistochemistry

Authors:

Chumachenko P.V.

Laboratoriia patomorfologii serdechno-sosudistykh zabolevaniĭ

Afanasyev M.A.

Russian Cardiology Research and Production Complex, Ministry of Health of the Russian Federation, Moscow, Russia

Galankina I.E.

Nauchno-issledovatel'skiĭ institut skoroĭ pomoshchi im. N.V. Sklifosovskogo, Moskva

Ilyina L.N.

Russian Cardiology Research and Production Complex, Ministry of Health of the Russian Federation, Moscow, Russia

Postnov A.Yu.

Institute of the Clinical Cardiology named after A.L. Myasnikov of National Medical Research Center for Cardiology, Moscow, Russia

List of references:

  1. Kawasaki T. Acute febrile mucocutaneous syndrome with lymphoid involvement with specific desquamation of the fingers and toes in children. Arerugi. 1967;16(3):178-222.
  2. Lyskina GA, Vinogradova OI, Shirinskaya OG, Bregel’ LV, Subbotin VM, Berns D. Klinicheskie rekomendatsii. Кlinika, diagnostika i lechenie sindroma Kavasaki. Moscow; 2011. Accessed 25 January 2017. (In Russ.)
  3. Rowley AH, Shulman ST, Mask C A, Finn LS, Terai M, Baker SC, Galliani C, Takahashi K, Naoe S, Kalelkar MB, Crawford SE. IgA plasma cell infiltration of proximal respiratory tract, pancreas, kidney, and coronary artery in acute Kawasaki disease. J Infect Dis. 2000;182(4):1183-1191. https://doi.org/10.1086/315832
  4. Brown TJ, Crawford SE, Cornwall ML, Garcia F, Shulman ST, Rowley AH. CD8 T lymphocytes and macrophages infiltrate coronary artery aneurysms in acute Kawasaki disease. J Infect Dis. 2001;184(7):940-943. https://doi.org/10.1086/323155
  5. Noval Rivas M, Lee Y, Wakita D, Chiba N, Dagvadorj J, Shimada K, Chen S, Fishbein MC, Lehman TJ, Crother TR, Arditi M. CD8+ T cells contribute to the development of coronary arteritis in the Lactobacillus casei cell wall extract-induced murine model of Kawasaki disease. Arthr Rheum. 2017;69(2):410-421. https://doi.org/10.1002/art.39939
  6. Yan Ding, Gang Li, Xiong LJ, Yin W, Liu J, Liu F, Wang RG, Xia K, Zhang SL, Zhao L. Profiles of responses of immunological factors to different subtypes of Kawasaki disease. BMC Musculoskeletal Disord. 2015;16:315. https://doi.org/10.1186/s12891-015-0744-6
  7. Matsubara T, Ichiyama T, Furukawa S. Immunological profile of peripheral blood lumphocytes and monocytes/macrophages in Kawasaki disease. Clin Exp Immunol. 2005;141(3):381-387. https://doi.org/ 10.1111/j.1365-2249.2005.02821.x
  8. Ehara H, Kiyohara K, Izumisawa Y, Ito T. Early activation does not translate into effector differentiation of peripheral CD 8 T cells during the acute phase of Kawasaki disease. Cell Immunol. 2010;265(1):57-64. https://doi.org/10.1016/j.cellimm.2010.07.003
  9. Ge X, Li CR, Yang J, Wang GB. Aberrantly decreased levels of NKG2D expression in children with Kawasaki disease. Scand J Immunol. 2013;77(5):389-397. https://doi.org/10.1111/sji.12022

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