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Kasim T.Kh.

Sechenov First Moscow State Medical University

Yavorovskiy A.G.

Sechenov First Moscow State Medical University (Sechenov University)

Mandel I.A.

Sechenov First Moscow State Medical University

Tereshin N.M.

Sechenov First Moscow State Medical University

Bairashevskaya A.V.

Sechenov First Moscow State Medical University

Nogtev P.V.

Sechenov First Moscow State Medical University

Kazakova S.S.

Sechenov First Moscow State Medical University

Posnov A.A.

Sechenov First Moscow State Medical University

Ognev O.O.

Sechenov First Moscow State Medical University

Prevention of acute kidney injury in cardiac surgery

Authors:

Kasim T.Kh., Yavorovskiy A.G., Mandel I.A., Tereshin N.M., Bairashevskaya A.V., Nogtev P.V., Kazakova S.S., Posnov A.A., Ognev O.O.

More about the authors

Journal: Russian Journal of Anesthesiology and Reanimatology. 2025;(2): 83‑89

DOI: 10.17116/anaesthesiology202502183

Views: 272

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Table of contents

PREVENTION OF ACUTE KIDNEY INJURY IN CARDIAC SURGERY
PREVENTION OF ACUTE KIDNEY INJURY IN CARDIAC SURGERY

To cite this article:

Kasim TKh, Yavorovskiy AG, Mandel IA, et al. . Prevention of acute kidney injury in cardiac surgery. Russian Journal of Anesthesiology and Reanimatology. 2025;(2):83‑89. (In Russ.)
https://doi.org/10.17116/anaesthesiology202502183

Подписка 2025-2 (АиР)
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More than 2 million on-pump cardiac surgeries are performed worldwide each year. These procedures are associated with acute kidney injury. To date, many studies are devoted to nephroprotective measures. A comprehensive approach to pre-, intra- and postoperative management was formed. This review summarizes data from studies investigating (goal-directed fluid therapy (GDFT), target DO2 strategy, KDIGO Bundle of Care), non-pharmacological (filters for leukodepletion, remote ischemic preconditioning) and pharmacological (dopamine and phenoldopam, dexmedetomidine, glucocorticosteroids, antioxidants, atrial natriuretic peptide) methods of kidney protection. Prospective directions in this field are considered (haptoglobin, QPI-1002 molecule, lithium, nitric oxide, acetaminophen and intravenous infusion of amino acids).

Keywords:

acute kidney injury
cardiopulmonary bypass
CS-AKI
nitric oxide
amino acids
nephroprotection

Authors:

Kasim T.Kh.

Sechenov First Moscow State Medical University

Yavorovskiy A.G.

Sechenov First Moscow State Medical University (Sechenov University)

Mandel I.A.

Sechenov First Moscow State Medical University

Tereshin N.M.

Sechenov First Moscow State Medical University

Bairashevskaya A.V.

Sechenov First Moscow State Medical University

Nogtev P.V.

Sechenov First Moscow State Medical University

Kazakova S.S.

Sechenov First Moscow State Medical University

Posnov A.A.

Sechenov First Moscow State Medical University

Ognev O.O.

Sechenov First Moscow State Medical University

Received:

15.09.2024

Accepted:

18.10.2024

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