Intraoperative and early postoperative respiratory function in patients with coronary artery disease undergoing on-pump or off-pump coronary artery bypass surgery

Zozulya M.V.; Lenkin A.I.; Sotnikov A.V.; Kurapeev I.S.; Saiganov S.A.; Lebedinskii K.M.

doi:https://doi.org/10.17116/anaesthesiology202004154

Zozulya M.V.

Mechnikov North-Western State Medical University

Lenkin A.I.

Mechnikov North-Western State Medical University

Sotnikov A.V.

Mechnikov North-Western State Medical University

Kurapeev I.S.

Mechnikov North-Western State Medical University

Saiganov S.A.

Mechnikov North-Western State Medical University

Lebedinskii K.M.

North-Western State Medical University n.a. Mechnikov, Federal Research;
Clinical Center of Intensive Care Medicine and Rehabilitology

SPIN RSCI: 3590-2308
Scopus AuthorID: 6602775085
ResearcherID: O-8655-2014
ORCID: 0000-0002-5752-4812

Intraoperative and early postoperative respiratory function in patients with coronary artery disease undergoing on-pump or off-pump coronary artery bypass surgery

Authors:

Zozulya M.V., Lenkin A.I., Sotnikov A.V., Kurapeev I.S., Saiganov S.A., Lebedinskii K.M.

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Journal: Russian Journal of Anesthesiology and Reanimatology. 2020;(4): 54‑60

DOI: 10.17116/anaesthesiology202004154

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To cite this article:

Zozulya MV, Lenkin AI, Sotnikov AV, Kurapeev IS, Saiganov SA, Lebedinskii KM. Intraoperative and early postoperative respiratory function in patients with coronary artery disease undergoing on-pump or off-pump coronary artery bypass surgery. Russian Journal of Anesthesiology and Reanimatology. 2020;(4):54‑60. (In Russ.)
https://doi.org/10.17116/anaesthesiology202004154

Использование инфографики авторами научных работ

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OBJECTIVE

To compare perioperative gas exchange in patients with coronary artery disease undergoing on-pump and off-pump coronary artery bypass surgery.

MATERIAL AND METHODS

Oxygenation and ventilation changes were studied in 48 patients who underwent elective coronary artery bypass grafting. Patients were divided into two groups (on-pump and off-pump coronary artery bypass surgery). Arterial blood gases were analyzed after intubation, at the end of surgery, after 2, 6, 12, 18 and 24 hours.

RESULTS

PaCO₂was similar in both groups and remained within reference values throughout the follow-up period. Oxygenation parameters (PaO₂ and SaO₂) were similar in both groups at the end of surgery. However, these values were significantly higher in 2, 6 and 12 hours after on-pump CABG (p<0.05). PaO₂/FiO₂ index was significantly lower in 2, 6, and 24 hours after off-pump CABG (p<0.05). Between-group analysis of mechanical ventilation time and postoperative morbidity did not reveal significant differences.

CONCLUSION

Off-pump CABG does not guarantee the absence or reduced incidence of postoperative respiratory complications. Intraoperative hemodynamic stabilization techniques can provoke significant gas exchange disturbances in postoperative period although their clinical significance requires further evaluation.

Keywords:

cardiac surgery

cardiopulmonary bypass

postoperative respiratory complications

intensive care

arterial blood gases

Authors:

Zozulya M.V.

Mechnikov North-Western State Medical University

Lenkin A.I.

Mechnikov North-Western State Medical University

Sotnikov A.V.

Mechnikov North-Western State Medical University

Kurapeev I.S.

Mechnikov North-Western State Medical University

Saiganov S.A.

Mechnikov North-Western State Medical University

Lebedinskii K.M.

North-Western State Medical University n.a. Mechnikov, Federal Research;
Clinical Center of Intensive Care Medicine and Rehabilitology

SPIN RSCI: 3590-2308
Scopus AuthorID: 6602775085
ResearcherID: O-8655-2014
ORCID: 0000-0002-5752-4812

Received:

11.05.2020

Accepted:

30.05.2020

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