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Shimansky V.N.

Burdenko Neurosurgical Center

Sultanov R.A.

Burdenko Neurosurgical Center

Tanyashin S.V.

Burdenko Neurosurgical Center

Golanov A.V.

Burdenko Neurosurgical Center

Galkin M.V.

Burdenko National Medical Research Center for Neurosurgery

Karnaukhov V.V.

Burdenko Neurosurgical Center

Danilov G.V.

Burdenko Neurosurgical Center

Strunina Yu.V.

Burdenko Neurosurgical Center

Surgical and combined treatment of patients with craniovertebral junction meningioma: a single-center retrospective study of 196 cases

Authors:

Shimansky V.N., Sultanov R.A., Tanyashin S.V., Golanov A.V., Galkin M.V., Karnaukhov V.V., Danilov G.V., Strunina Yu.V.

More about the authors

Journal: Burdenko's Journal of Neurosurgery. 2023;87(2): 22‑29

DOI: 10.17116/neiro20238702122

Read: 2291 times

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Table of contents

SURGICAL AND COMBINED TREATMENT OF PATIENTS WITH CRANIOVERTEBRAL JUNCTION MENINGIOMA: A SINGLE-CENTER RETROSPECTIVE STUDY OF 196 CASES
SURGICAL AND COMBINED TREATMENT OF PATIENTS WITH CRANIOVERTEBRAL JUNCTION MENINGIOMA: A SINGLE-CENTER RETROSPECTIVE STUDY OF 196 CASES

To cite this article:

Shimansky VN, Sultanov RA, Tanyashin SV, et al. . Surgical and combined treatment of patients with craniovertebral junction meningioma: a single-center retrospective study of 196 cases. Burdenko's Journal of Neurosurgery. 2023;87(2):22‑29. (In Russ., In Engl.)
https://doi.org/10.17116/neiro20238702122

Подписка 2025-2 (Burdenko's Journal of Neurosurgery)
 
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Treatment of craniovertebral junction meningioma is a difficult task. Surgical treatment is the gold standard for these patients. However, it is associated with high risk of neurological impairment, while combined treatment (surgery + radiotherapy) provides more favorable outcomes.

OBJECTIVE

To present the results of surgical and combined treatment of patients with craniovertebral junction meningioma.

MATERIAL AND METHODS

There were 196 patients with craniovertebral junction meningioma who underwent surgical or combined (surgery + radiotherapy) treatment at the Burdenko Neurosurgery Center between January 2005 and June 2022. The sample included 151 women and 45 men (3.4:1). Resection of tumor was performed in 97.4% of patients, craniovertebral junction decompression with dural defect closure — 2%, ventriculoperitoneostomy — 0.5%. As the second stage, 40 patients (20.4%) underwent radiotherapy.

RESULTS

Total resection was achieved in 106 patients (55.2%), subtotal — 63 (32.8%), partial — 20 (10.4%), tumor biopsy was performed in 3 (1.6%) cases. Intraoperative complications occurred in 8 patients (4%), postoperative complications — in 19 (9.7%) cases. Radiosurgery was carried out in 6 (15%) patients, hypofractionated irradiation — 15 (37.5%), standard fractionation — 19 (47.5%) patients. Tumor growth control after combined treatment made up 84%.

CONCLUSION

Clinical outcomes in patients with craniovertebral junction meningioma depend on tumor dimensions, topographic and anatomical localization of tumor, resection quality and relationship with surrounding structures. Combined treatment of anterior and anterolateral meningiomas of the craniovertebral junction is preferable compared to total resection.

Keywords:

meningioma
craniovertebral junction
skull base tumor
posterior cranial fossa
combined treatment
radiosurgery

Authors:

Shimansky V.N.

Burdenko Neurosurgical Center

Sultanov R.A.

Burdenko Neurosurgical Center

Tanyashin S.V.

Burdenko Neurosurgical Center

Golanov A.V.

Burdenko Neurosurgical Center

Galkin M.V.

Burdenko National Medical Research Center for Neurosurgery

Karnaukhov V.V.

Burdenko Neurosurgical Center

Danilov G.V.

Burdenko Neurosurgical Center

Strunina Yu.V.

Burdenko Neurosurgical Center

Received:

14.11.2022

Accepted:

27.01.2023

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