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Mikhailov N.I.

Herzen Moscow Oncology Research, Branch of the National Medical Research Center of Radiology

Zaitsev A.M.

Herzen Moscow Oncology Research, Branch of the National Medical Research Center of Radiology

Kucheryavykh M.A.

Herzen Moscow Oncology Research, Branch of the National Medical Research Center of Radiology

Petrova P.Yu.

Herzen Moscow Oncology Research, Branch of the National Medical Research Center of Radiology

Kirsanova O.N.

Herzen Moscow Oncology Research, Branch of the National Medical Research Center of Radiology

Kosumova Kh.S.

Herzen Moscow Oncology Research, Branch of the National Medical Research Center of Radiology

Metastatic meningiomas: a case series and literature review

Authors:

Mikhailov N.I., Zaitsev A.M., Kucheryavykh M.A., Petrova P.Yu., Kirsanova O.N., Kosumova Kh.S.

More about the authors

Journal: Burdenko's Journal of Neurosurgery. 2025;89(3): 83‑91

DOI: 10.17116/neiro20258903183

Read: 1609 times

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Table of contents

METASTATIC MENINGIOMAS: A CASE SERIES AND LITERATURE REVIEW
METASTATIC MENINGIOMAS: A CASE SERIES AND LITERATURE REVIEW

To cite this article:

Mikhailov NI, Zaitsev AM, Kucheryavykh MA, Petrova PYu, Kirsanova ON, Kosumova KhS. Metastatic meningiomas: a case series and literature review. Burdenko's Journal of Neurosurgery. 2025;89(3):83‑91. (In Russ., In Engl.)
https://doi.org/10.17116/neiro20258903183

Подписка 2025 Журнал «Вопросы нейрохирургии» имени Н.Н. Бурденко (Burdenko's Journal of Neurosurgery)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

BACKGROUND

The probability of meningiomas metastasizing is 0.18%, and the causes are unclear. The most common localizations of extracranial metastases are lung (37.2%), bones (16.5%) and liver (9.2%). There are no effective treatment algorithms for metastatic meningiomas. Treatment tactics consists of symptomatic surgery and radiotherapy.

MATERIAL AND METHODS

We present 3 patients including a 75-year-old woman with grade 1 meningioma and metastasis to occipital lymph node, a 59-year-old man with meningioma grade 2 and lung metastasis, a 45-year-old woman with grade 2 meningioma with extracranial component and lung metastasis.

RESULTS AND DISCUSSION

A female patient with grade 1 meningioma and occipital lymph node metastasis showed clinical stabilization after surgical treatment. The follow-up was 14 months. Treatment with nitrosourea was ineffective for metastatic lung lesions in a patient with grade II meningioma. Combination of bevacizumab and everolimus in a patient with G2 meningioma within craniovertebral junction and metastatic lung lesion achieved stabilization in all foci. The follow-up was 6 months.

CONCLUSION

It is necessary to continue accumulation of clinical experience due to rarity of meningioma metastasizing. Treatment of such patients remains individual.

Keywords:

metastasis
meningioma
meningioma metastasis

Authors:

Mikhailov N.I.

Herzen Moscow Oncology Research, Branch of the National Medical Research Center of Radiology

Zaitsev A.M.

Herzen Moscow Oncology Research, Branch of the National Medical Research Center of Radiology

Kucheryavykh M.A.

Herzen Moscow Oncology Research, Branch of the National Medical Research Center of Radiology

Petrova P.Yu.

Herzen Moscow Oncology Research, Branch of the National Medical Research Center of Radiology

Kirsanova O.N.

Herzen Moscow Oncology Research, Branch of the National Medical Research Center of Radiology

Kosumova Kh.S.

Herzen Moscow Oncology Research, Branch of the National Medical Research Center of Radiology

Received:

17.01.2025

Accepted:

28.03.2025

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References:

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