Case report of a &amp;quot;probable&amp;quot; cerebral amyloid angiopathy

Mirsadykov D.A.; Abdumazhitova M.M.; Arifzhanov I.A.

doi:https://doi.org/

Mirsadykov D.A.

Kafedra travmatologii, ortopedii s kursom neĭrokhirurgii Tashkentskogo pediatricheskogo meditsinskogo instituta;
otdelenie neĭrokhirurgii Tashkentskogo oblastnogo mnogoprofil'nogo meditsinskogo tsentra

Abdumazhitova M.M.

Arifzhanov I.A.

Case report of a "probable" cerebral amyloid angiopathy

Authors:

Mirsadykov D.A., Abdumazhitova M.M., Arifzhanov I.A.

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Journal: Burdenko's Journal of Neurosurgery. 2013;77(1): 46‑52

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To cite this article:

Mirsadykov DA, Abdumazhitova MM, Arifzhanov IA. Case report of a "probable" cerebral amyloid angiopathy. Burdenko's Journal of Neurosurgery. 2013;77(1):46‑52. (In Russ., In Engl.)

Подписка 2025 Журнал «Вопросы нейрохирургии» имени Н.Н. Бурденко (Burdenko's Journal of Neurosurgery)

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Abstract:

Sixty-two year old man was admitted to the department of neurosurgery after stroke episode. CT-scan revealed non-traumatic, non-hypertensive intracerebral hemorrhage in the left temporal lobe; cerebral amyloid angiopathy was suspected. Initially, according to Boston criteria, intracerebral hematoma was interpreted as a result of a "probable" cerebral amyloid angiopathy. Surgical evacuation of the hematoma lead to the partial recourse of speech and cognitive deficit. Four weeks after stroke onset and 3 weeks after surgery CT was performed, which revealed intracerebral hematoma in the right parietal lobe; this fact let to diagnose "probable" cerebral amyloid angiopathy. The second hematoma was evacuated, and surgical treatment together with medical therapy improved patient's quality of life. Treatment strategy for the intracerebral hematomas resulting from cerebral amyloid angiopathy has not been justified yet, which requires further investigations.

Keywords:

cerebral amyloid angiopathy

recurrent lobar hemorrhages

geriatric patients

gyrus temporalis superior

gyrus supramarginalis

surgical treatment

Authors:

Mirsadykov D.A.

Abdumazhitova M.M.

Arifzhanov I.A.

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References:

Bekov D.B., Mikhailov S.S. Atlas of arteries and veins of the human brain. Moscow: Meditsina, 1979; 289. In Russian.
Bugrova S.G. Pathogenetic mechanisms of formation of cognitive disorders in patients with dyscirculatory encephalopathy, differential diagnostics with Alzheimer’s disease, hospital treatment. Summary of the Doctor of Medicine. Ivanovo, 2011; 43. In Russian.
Burenchev D.V. Magnetic resonance imaging in patients with acute hemorrhagic stroke. Summary of the Doctor of Medicine Thesis. Moscow, 2010; 45. In Russian.
Galkina T.N. Organization of medical aid and multifactor analysis of the outcomes of nontraumatic intracerebral hemorrhages. Summary of the Candidate of Medicine Thesis. St. Petersburg, 2000; 24. In Russian.
Greenberg M.S. Handbook of Neurosurgery. Fifth Ed., Moscow, 2010; 1008. In Russian.
Dash’yan V.G. Surgical treatment of hemorrhagic stroke. Summary of the Doctor of Medicine Thesis. Moscow, 2009; 47. In Russian.
Dzyak L.A., Zorin N.A., Plyushchev I.E. Choice of treatment strategy in patients with hypertensive intracerebral (hemispheric) hemorrhages. Ukr Neirokhirur Zhurn 2002; 4: 76—81. In Russian.
Dralyuk M.G., Shnyakin P.G., Samotesov P.A., Merkushev Yu.A., Khorzhevsky V.A., Karlova E.A., Ermakova I.E., Galats K.A. Nontraumatic intracerebral hemorrhages: pathomorphological variants of structure and opportunities for neuroimaging. Review. Ros Neirokhirur Zhurn 2012; 4: 1: 87—91. In Russian.
Kalashnikova L.A. Cerebral amyloid angiopathy. Zhurn Nevrol Psikhiat 2008; 108: 9: 86—90. In Russian.
Konovalov A.N., Blinkov S.M., Putsillo M.V. Atlas of neurosurgical anatomy. Moscow: Meditsina, 1990; 336. In Russian.
Krotenkova M.V., Diagnostics of acute stroke: neuroimaging algorithms. Summary of the Doctor of Medicine Thesis. Moscow, 2011; 45. In Russian.
Lebedev V.V., Krylov V.V. Emergency neurosurgery. Handbook for physicians. Moscow: Meditsina, 2000; 568. In Russian.
Ponomarev V.A. Prognosis of surgical treatment in patients with hemorrhagic stroke. Summary of the Candidate of Medicine Thesis. Moscow, 1998; 41. In Russian.
Skvortsova V.I., Krylova V.V. Hemorrhagic stroke: Practical guide. Moscow: GEOTAR-Media, 2005; 160. In Russian.
Sokolova L.P. Features of neurometabolism and brain perfusion from the perspective of pathogenetic mechanisms of formation of pre-dementia cognitive disorders of different genesis. Summary of the Doctor of Medicine Thesis. Moscow, 2012; 50. In Russian.
Sturova Yu.V., Antipova L.N., Malakhov A.A., Dryaeva L.G. Cerebral amyloid angiopathy as an etiological factor of hemorrhagic stroke in elderly patients. Vestn Municipalnogo Zdravookhr 2010; 1:1—16. URL http://vestnik.kmldo.ru/archive.
Suvorova I.A. Vascular dementia: clinical course, risk factors, differentiated therapy. Summary of the Doctor of Medicine Thesis. Irkutsk, 2011; 46. In Russian.
Chebotareva N.M. Surgical treatment of intracerebral hemorrhages caused by arterial hypertension. Moscow: Meditsina, 1984; 176. In Russian.
Shakhparonova N.V. Post-stroke abnormalities of the higher functions: phenomenology, prognosis, rehabilitation. Summary of the Doctor of Medicine Thesis. Moscow, 2011; 48. In Russian.
Peripheral nervous system disorders. Ed. by A.K. Asbury, R.W. Gilliat. Moscow: Meditsina, 1987; 352. In Russian (translated from English).
Broderick J., Connoly S., Feldman E. et al. Guidelines for the management of spontaneous intracerebral hemorrhage in adults. Stroke 2007; 38: 2001—2023.
Chao C.P., Kotsenas A.L., Broderick D.F. Cerebral amyloid angiopathy: CT and MR imaging findings. Radiographics 2006; 26: 5: 1517—1531.
Chen Y.W., Gurol M.E., Rosand J. et al. Progression of white matter lesions and hemorrhages in cerebral amyloid angiopathy. Neurology 2006; 67: l: 83—87.
Ferrer I., Rovira M.B., Sanchez-Guerra M.L. et al. Neuropathology and patho- genesis of encephalitis following amyloid-beta immunization in Alzheimer’s disease. Brain Pathol 2004; 14: 11—20.
Gilles C., Brucher J.M., Khoubesserian P. et al. Cerebral amyloid angiopathy as s cause of multiple intracerebral hemorrhages. Neurology 1984; 34: 730—735.
Gray F., Dubas F., Roullet E., Escourolle R. Leukoencephalopathy in diffuse hemorrhagic cerebral amyloid angiopathy. Ann Neurol 1985; 18: 54—59.
Greenberg S.M., Vonsattel J.P., Stakes J.W. et al. The clinical spectrum of cerebral amyloid angiopathy: presentation without lobar hemorrhage. Neu- rology 1993; 43: 2073—2079.
Greenberg S.M., Vonsattel J.P. Diagnosis of cerebral amiloid angiopathy. Sensitivity and specificity of cortical biopsy. Stroke 1997; 28: 1418—1422.
Greenberg S.M. Cerebral amiloid angiopathy. Prospects for clinical diagno- sis and treatment. Neurology 1998; 51: 690—694.
Gurol M.E., Irizzary M.C., Smith E.E. et al. Plasma P-amiloid and white matter lesions in AD, MCI, and cerebral amyloid angiopathy. Neurology 2006; 66: 23—29.
Haglund M., Englund E. Cerebral amyloid angiopathy, white matter lesions and Alzheimer encephalopathy — a histopathological assessment. Dement Geriatr Cogn Dis 2002; 14: 161—166.
Ishihara J., Jakahashi M., Yokota J. et al. The significance of cerebrovascular amyloid in the aetiology of superficial (lobar) cerebral hemorrhage and its incidence in the elderly population. J Pathol 1991; 165: 3: 229—234.
Jellinger K.A., Lauda F., Attems J. Sporadic cerebral amyloid angiopathy is not a frequent cause of spontaneous brain hemorrhage. Eur J Neurol 2007; 14: 8: 923—928.
Johnson K.A., Gregas M., Becker J.A. et al. Imaging of amyloid burden and distribution in cerebral amyloid angiopathy. Ann Neurol 2007; 62: 3: 229— 234.
Kinnecom C., Lev M.H., Wendell L. et al. Course of cerebral amyloid angi- opathy — related inflammation. Neurology 2007; 68: 1411—1416.
Knudsen K.A., Rosand J., Karluk D., Greenberg S.M. Clinical diagnosis of cerebral amyloid angiopathy: Validation of the Boston Criteria. Neurology 2001; 56: 537—539.
Maia L.F., Vasconcelos C., Seixas S. et al. Lobar brain hemorrhages and white matter changes: Clinical, radiological and laboratorial profiles. Cere- brovasc Dis 2006; 22: 2—3: 155—161.
Pfeifer L.A., White L.R., Ross G.W. et al. Cerebral amyloid angiopathy and cognitive function: the HAAS autopsy study. Neurology 2002; 58: 1629— 1634.
Roullet E., Gray F.F. Leuko-araiosis in severe amyloid angiopathy. Arch Neurol 1988; 45: 140.
Salat D.H., Smith Е.Е., Tuch D.S. et al. White matter alterations in cerebral amyloid angiopathy measured by diffusion tensor imaging. Stroke 2006; 37: 7: 1759—1764.
Smith E.E., Gurol M.E., Eng J.A. et al. White matter lesions, cognition, and recurrent hemorrhage in lobar intracerebral hemorrhage. Neurology 2004; 63: 1606—1612.
Vernooij M.W., van der Lugt A., Icram M.A. Prevalence and risk factors of cerebral microbleeds: The Rotterdam Scan Study. J Neurol 2008; 70: 1208—1214.
Vinters H.V. Cerebral amiloid angiopathy: a critical review. Stroke 1987; 18: 311—324.
Zhang-Nunes S.X., Maat-Schieman M.L., van Duinen S.G. et al. The cerebral beta-amyloid angiopathies: hereditary and sporadic. Brain Pathol 2006; 16: 1: 30—39.