Quantitative electroencephalogram in females at different stages of alcohol remission

Bokhan N.A.; Galkin S.A.; Kisel N.I.; Mandel A.I.

doi:https://doi.org/10.17116/jnevro2025125081122

Bokhan N.A.

Mental Health Research Institute — Tomsk National Research Medical Center Russian Academy of Science;
Siberian State Medical University

ORCID: 0000-0002-1052-855X

Galkin S.A.

Mental Health Research Institute — Tomsk National Research Medical Center Russian Academy of Science

ORCID: 0000-0002-7709-3917

Kisel N.I.

Mental Health Research Institute — Tomsk National Research Medical Center Russian Academy of Sciences

ORCID: 0000-0001-5573-9775

Mandel A.I.

Mental Health Research Institute — Tomsk National Research Medical Center Russian Academy of Sciences

ORCID: 0000-0002-6020-6604

Quantitative electroencephalogram in females at different stages of alcohol remission

Authors:

Bokhan N.A., Galkin S.A., Kisel N.I., Mandel A.I.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2025;125(8): 122‑126

DOI: 10.17116/jnevro2025125081122

Read: 747 times

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To cite this article:

Bokhan NA, Galkin SA, Kisel NI, Mandel AI. Quantitative electroencephalogram in females at different stages of alcohol remission. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;125(8):122‑126. (In Russ.)
https://doi.org/10.17116/jnevro2025125081122

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)

Использование инфографики авторами научных работ

OBJECTIVE

To conduct a comparative analysis of the spectral parameters of the electroencephalogram (EEG) in females at different stages of alcohol remission.

MATERIAL AND METHODS

Sixty EEGs from female patients diagnosed with alcohol dependence were analyzed. At the time of enrollment in the study, the patients were at different stages of remission: the alcohol-deprivation stage (Group 1), the remission stabilization stage (Group 2), and the established remission stage (Group 3).

RESULTS

Statistical analysis of the EEG power spectrum revealed higher values in the alpha range for Group 3 patients in the occipital lead (O1: p=0.011 and p=0.027) and temporal leads (T5: p=0.001 and p=0.012; T6: p=0.022 and p=0.029) compared to Group 1 and Group 2 patients, respectively. Statistically significantly higher values of the power spectrum in the beta range were also found for Group 3 patients in the frontal (F7: p=0.001; F8: p=0.002), parietal (P3: p=0.041; P4: p=0.045 and p=0.043), occipital (O1: p=0.002; O2: p=0.008 and p=0.003), and temporal (T5: p=0.002 and p=0.001; T6: p=0.001 and p<0.001) leads. There were no statistically significant differences in quantitative parameters of EEG power spectrum between Groups 1 and 2 (p>0.05).

CONCLUSION

The results of the comparative analysis indicate a significant restructuring of the functional state of the brain in females only after 1 year of abstinence from alcohol.

Keywords:

alcoholism

remission

electroencephalogram

topographic mapping

power spectrum

Authors:

Bokhan N.A.

Mental Health Research Institute — Tomsk National Research Medical Center Russian Academy of Science;
Siberian State Medical University

ORCID: 0000-0002-1052-855X

Galkin S.A.

Mental Health Research Institute — Tomsk National Research Medical Center Russian Academy of Science

ORCID: 0000-0002-7709-3917

Kisel N.I.

Mental Health Research Institute — Tomsk National Research Medical Center Russian Academy of Sciences

ORCID: 0000-0001-5573-9775

Mandel A.I.

Mental Health Research Institute — Tomsk National Research Medical Center Russian Academy of Sciences

ORCID: 0000-0002-6020-6604

Received:

01.04.2025

Accepted:

14.05.2025

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