Features of parameters of cerebral hemodynamics in patients with alcoholism with different flexibility of cognitive functions

Galkin S.A.; Oshkina T.A.

doi:https://doi.org/10.17116/jnevro202512502196

Galkin S.A.

Mental Health Research Institute — Tomsk National Research Medical Center Russian Academy of Science

ORCID: 0000-0002-7709-3917

Oshkina T.A.

Mental Health Research Institute — Tomsk National Research Medical Center Russian Academy of Science

ORCID: 0000-0003-0927-0050

Features of parameters of cerebral hemodynamics in patients with alcoholism with different flexibility of cognitive functions

Authors:

Galkin S.A., Oshkina T.A.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2025;125(2): 96‑100

DOI: 10.17116/jnevro202512502196

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To cite this article:

Galkin SA, Oshkina TA. Features of parameters of cerebral hemodynamics in patients with alcoholism with different flexibility of cognitive functions. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;125(2):96‑100. (In Russ.)
https://doi.org/10.17116/jnevro202512502196

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)

Использование инфографики авторами научных работ

OBJECTIVE

To study the parameters of regional cerebral hemodynamics in patients with alcoholism with different flexibility of cognitive functions.

MATERIAL AND METHODS

Fifty-eight patients with alcoholism were examined. The flexibility of cognitive functions was evaluated using the Stroop test. Regional cerebral hemodynamics was assessed by 4-channel rheoencephalography (REG).

RESULTS

It was found that 77.6% (n=45) of patients have low flexibility of cognitive processes. At physiological rest, patients with low cognitive flexibility had a significantly lower value of the rheographic index on the left and right in the carotid and vertebrobasilar basins compared with patients with a high level of cognitive flexibility (p<0.05). Also, in patients with a low level of cognitive flexibility, an asymmetry of vascular tone with higher on the right in both brain basins (p=0.079 and p=0.094) was demonstrated.

CONCLUSIONS

Regardless of the flexibility of cognitive processes, in patients with alcoholism, a hypovolemic, hyper-resistant type of cerebral hemodynamics was detected during withdrawal. In patients with a low level of flexibility of cognitive functioning, more pronounced compression effects on hemodynamics and moderate interhemispheric asymmetry of the tone of the internal carotid and vertebrobasilar arteries were observed.

Keywords:

alcoholism

flexibility of cognitive functions

brain hemodynamics

Authors:

Galkin S.A.

Mental Health Research Institute — Tomsk National Research Medical Center Russian Academy of Science

ORCID: 0000-0002-7709-3917

Oshkina T.A.

Mental Health Research Institute — Tomsk National Research Medical Center Russian Academy of Science

ORCID: 0000-0003-0927-0050

Received:

09.03.2023

Accepted:

16.04.2024

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