Features of parameters of cerebral hemodynamics in patients with alcoholism with different flexibility of cognitive functions

Galkin S.A.

Mental Health Research Institute — Tomsk National Research Medical Center Russian Academy of Science

ORCID: 0000-0002-7709-3917

Oshkina T.A.

Mental Health Research Institute — Tomsk National Research Medical Center Russian Academy of Science

ORCID: 0000-0003-0927-0050

Features of parameters of cerebral hemodynamics in patients with alcoholism with different flexibility of cognitive functions

Authors:

Galkin S.A., Oshkina T.A.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2025;125(2): 96‑100

DOI: 10.17116/jnevro202512502196

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To cite this article:

Galkin SA, Oshkina TA. Features of parameters of cerebral hemodynamics in patients with alcoholism with different flexibility of cognitive functions. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;125(2):96‑100. (In Russ.)
https://doi.org/10.17116/jnevro202512502196

Подписка 2025-2 (S.S. Korsakov Journal of Neurology and Psychiatry)

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OBJECTIVE

To study the parameters of regional cerebral hemodynamics in patients with alcoholism with different flexibility of cognitive functions.

MATERIAL AND METHODS

Fifty-eight patients with alcoholism were examined. The flexibility of cognitive functions was evaluated using the Stroop test. Regional cerebral hemodynamics was assessed by 4-channel rheoencephalography (REG).

RESULTS

It was found that 77.6% (n=45) of patients have low flexibility of cognitive processes. At physiological rest, patients with low cognitive flexibility had a significantly lower value of the rheographic index on the left and right in the carotid and vertebrobasilar basins compared with patients with a high level of cognitive flexibility (p<0.05). Also, in patients with a low level of cognitive flexibility, an asymmetry of vascular tone with higher on the right in both brain basins (p=0.079 and p=0.094) was demonstrated.

CONCLUSIONS

Regardless of the flexibility of cognitive processes, in patients with alcoholism, a hypovolemic, hyper-resistant type of cerebral hemodynamics was detected during withdrawal. In patients with a low level of flexibility of cognitive functioning, more pronounced compression effects on hemodynamics and moderate interhemispheric asymmetry of the tone of the internal carotid and vertebrobasilar arteries were observed.

Keywords:

alcoholism

flexibility of cognitive functions

brain hemodynamics

Authors:

Galkin S.A.

Mental Health Research Institute — Tomsk National Research Medical Center Russian Academy of Science

ORCID: 0000-0002-7709-3917

Oshkina T.A.

Mental Health Research Institute — Tomsk National Research Medical Center Russian Academy of Science

ORCID: 0000-0003-0927-0050

Received:

09.03.2023

Accepted:

16.04.2024

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