The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-4329
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Danilov A.B.

Sechenov First Moscow State Medical University (Sechenov University)

Kukushkin M.L.

Research Institute of General Pathology and Pathophysiology

Suponeva N.A.

Research Center of Neurology

Amelin A.V.

Pavlov First Saint Petersburg State Medical University

Zhivolupov S.A.

Kirov Military medical academy

Shirokov V.A.

Erisman Federal Scientific Center of Hygiene

Davydov O.S.

Institute of General Pathology and Pathophysiology

Strokov I.A.

Sechenov First Moscow State Medical University (Sechenov University)

Churyukanov M.V.

Sechenov First Moscow State Medical University

Kozlov I.G.

Sechenov First Moscow State Medical University (Sechenov University)

Role and place of ipidacrine in the therapy of diseases of the peripheral nervous system. The resolution of the expert council

Authors:

Danilov A.B., Kukushkin M.L., Suponeva N.A., Amelin A.V., Zhivolupov S.A., Shirokov V.A., Davydov O.S., Strokov I.A., Churyukanov M.V., Kozlov I.G.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2024;124(2): 158‑164

DOI: 10.17116/jnevro2024124021158

Read: 3926 times

Download PDF (RU)
Contact the author
Table of contents

ROLE AND PLACE OF IPIDACRINE IN THE THERAPY OF DISEASES OF THE PERIPHERAL NERVOUS SYSTEM. THE RESOLUTION OF THE EXPERT COUNCIL
ROLE AND PLACE OF IPIDACRINE IN THE THERAPY OF DISEASES OF THE PERIPHERAL NERVOUS SYSTEM. THE RESOLUTION OF THE EXPERT COUNCIL

To cite this article:

Danilov AB, Kukushkin ML, Suponeva NA, et al. . Role and place of ipidacrine in the therapy of diseases of the peripheral nervous system. The resolution of the expert council. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;124(2):158‑164. (In Russ.)
https://doi.org/10.17116/jnevro2024124021158

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Recommended articles:
Control of neuropathic pain in lumbosacral dorsalgia. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(11):152-157
Neurological complications resu­lting of nitrous oxide into­xication. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(12):41-46
Algo­rithm for the diagnosis and treatment of patients with diabetic poly­neuropathy. Expert Council Reso­lution (March 1, 2025). S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(8):102-113
Main dire­ctions in corneal nerve fibers research. Russian Annals of Ophthalmology. 2024;(6):118-124
Intraneural ganglion of the pero­neal nerve: a case report and review. Russian Journal of Pain. 2025;(3):66-72
Abstract:

The resolution of the expert council is devoted to discussing aspects of the use of ipidacrine for the treatment of mononeuropathies, polyneuropathies and radiculopathies of various etiologies. Specialists prepared recommendations for ipidacrine’s application in treating peripheral nervous system disorders.

Keywords:

peripheral neuropathy
mononeuropathy
polyneuropathy
radiculopathy
ipidacrine

Authors:

Danilov A.B.

Sechenov First Moscow State Medical University (Sechenov University)

Kukushkin M.L.

Research Institute of General Pathology and Pathophysiology

Suponeva N.A.

Research Center of Neurology

Amelin A.V.

Pavlov First Saint Petersburg State Medical University

Zhivolupov S.A.

Kirov Military medical academy

Shirokov V.A.

Erisman Federal Scientific Center of Hygiene

Davydov O.S.

Institute of General Pathology and Pathophysiology

Strokov I.A.

Sechenov First Moscow State Medical University (Sechenov University)

Churyukanov M.V.

Sechenov First Moscow State Medical University

Kozlov I.G.

Sechenov First Moscow State Medical University (Sechenov University)

Received:

30.01.2024

Accepted:

02.02.2024

Close metadata

References:

  1. Bogov AA, Masgutov RF, Khannanova IG, et al. Carpal canal syndrome. Prakticheskaya medicina. 2014;2(4):80. (In Russ.).
  2. Shirokov VA, Kochurova LL. Occupational risks of carpal tunnel syndrome development in railway workers. Russian Journal of Occupational Health and Industrial Ecology. 2017;(9):220-221. (In Russ.).
  3. Genova A, Dix O, Saefan A, et al. Carpal Tunnel Syndrome: A Review of Literature. Cureus. 2020;12(3):e7333. https://doi.org/10.7759/cureus.7333
  4. Osterman M, Ilyas AM, Matzon JL. Carpal tunnel syndrome in pregnancy. Orthop Clin North Am. 2012;43(4):515-520.  https://doi.org/10.1016/j.ocl.2012.07.020
  5. Gilweg AS, Parfenov VA. Carpal tunnel syndrome in old age. DoctorRu. 2017;1(130):30-34. (In Russ.).
  6. Wade RG, Griffiths TT, Flather R, et al. Safety and Outcomes of Different Surgical Techniques for Cubital Tunnel Decompression: A Systematic Review and Network Meta-analysis. JAMA Netw Open. 2020;3(11):e2024352. https://doi.org/10.1001/jamanetworkopen.2020.24352
  7. Mondelli M, Giannini F, Ballerini M, et al. Incidence of ulnar neuropathy at the elbow in the province of Siena (Italy). J Neurol Sci. 2005;234(1-2):5-10.  https://doi.org/10.1016/j.jns.2005.02.010
  8. Latinovic R, Gulliford MC, Hughes RA. Incidence of common compressive neuropathies in primary care. J Neurol Neurosurg Psychiatry. 2006;77(2):263-265.  https://doi.org/10.1136/jnnp.2005.066696
  9. Konstantinou K, Dunn KM. Sciatica: review of epidemiological studies and prevalence estimates. Spine (Phila Pa 1976). 2008;33(22):2464-2472. https://doi.org/10.1097/BRS.0b013e318183a4a2
  10. Levin OS. Polinevropatii. Klinicheskoe rukovodstvo. M.: Medicinskoe infomacionnoe agentstvo. 2016. (In Russ.).
  11. Antipenko EA, Sedyshev DV. Painful polyneuropathies. RMJ. 2017;21:1543-1547. (In Russ.).
  12. Beghi E, Simone P, Apollo F, et al. Polyneuropathy in an adult hospital population. Assessment of the prevalence through a simple screening procedure. Neuroepidemiology. 1988;7(1):23-28.  https://doi.org/10.1159/000110132
  13. Liashenko EA, Levin OS. Peripheral neuropathies at advanced age. Sovremennaya terapiya v psikhiatrii i nevrologii. 2014;2:37-44. (In Russ.).
  14. Franklin GM, Kahn LB, Baxter J, et al. Sensory neuropathy in non-insulin-dependent diabetes mellitus. The San Luis Valley Diabetes study. Am J Epidemiol. 1990;131:633-643.  https://doi.org/10.1093/oxfordjournals.aje.a115547
  15. Verghese J, Bieri PL, Gellido C, et al. Peripheral neuropathy in young-old and old-old patients. Muscle Nerve. 2001;24(11):1476-1481. https://doi.org/10.1002/mus.1171
  16. Parfenov VA, Yakhno NN, Davydov OS, et al. Discogenic lumbosacral radiculopathy. Recommendations of the Russian Association for the Study of Pain (RSSP). Neurology, Neuropsychiatry, Psychosomatics. 2020;12(4):15-24. (In Russ.). https://doi.org/10.14412/2074-2711-2020-4-15-24
  17. Zhivolupov SA, Bardakov SN, Samartsev IN, et al. The role of cholinesterase inhibitors in optimization of brain`s vascular pathology treatment (theoretical basis and clinical phenomenology). Zhurnal Nevrologii i Psikhiatrii im. S.S. Korsakova. 2014;114(8-2):57-64. (In Russ.).
  18. Piovesana R, Reid AJ, Tata AM. Emerging Roles of Cholinergic Receptors in Schwann Cell Development and Plasticity. Biomedicines. 2022;11(1):41.  https://doi.org/10.3390/biomedicines11010041
  19. Chang EH, Chavan SS, Pavlov VA. Cholinergic Control of Inflammation, Metabolic Dysfunction, and Cognitive Impairment in Obesity-Associated Disorders: Mechanisms and Novel Therapeutic Opportunities. Front Neurosci. 2019;13:263.  https://doi.org/10.3389/fnins.2019.00263
  20. Kume T, Takada-Takatori Y. Nicotinic acetylcholine receptor signaling: Roles in neuroprotection. In: Akaike A, Shimohama S, Misu Y, eds. Nicotinic Acetylcholine Receptor Signaling in Neuroprotection. Springer; Singapore: 2018.
  21. Ho TNT, Abraham N, Lewis RJ. Structure-Function of Neuronal Nicotinic Acetylcholine Receptor Inhibitors Derived From Natural Toxins. Front Neurosci. 2020;14:609005. https://doi.org/10.3389/fnins.2020.609005
  22. Ockenga W, Kühne S, Bocksberger S, et al. Non-neuronal functions of the m2 muscarinic acetylcholine receptor. Genes (Basel). 2013;4(2):171-197.  https://doi.org/10.3390/genes4020171
  23. Pandey S, Mudgal J. A Review on the Role of Endogenous Neurotrophins and Schwann Cells in Axonal Regeneration. J Neuroimmune Pharmacol. 2022;17(3-4):398-408.  https://doi.org/10.1007/s11481-021-10034-3
  24. Lee EH, Seo SR. Neuroprotective roles of pituitary adenylate cyclase-activating polypeptide in neurodegenerative diseases. BMB Rep. 2014;47(7):369-375.  https://doi.org/10.5483/bmbrep.2014.47.7.086
  25. Verdiyan EE, Allakhverdiev ES, Maksimov GV. Study of the Peripheral Nerve Fibers Myelin Structure Changes during Activation of Schwann Cell Acetylcholine Receptors. PLoS One. 2016;11(7):e0158083. https://doi.org/10.1371/journal.pone.0158083
  26. Salazar Intriago MS, Piovesana R, Matera A, et al. The Mechanisms Mediated by α7 Acetylcholine Nicotinic Receptors May Contribute to Peripheral Nerve Regeneration. Molecules. 2021;26(24):7668. https://doi.org/10.3390/molecules26247668
  27. Naser PV, Kuner R. Molecular, Cellular and Circuit Basis of Cholinergic Modulation of Pain. Neuroscience. 2018;387:135-148.  https://doi.org/10.1016/j.neuroscience.2017.08.049
  28. Sullere S, A Kunczt A, McGehee DS. A cholinergic circuit that relieves pain despite opioid tolerance. Neuron. 2023;111:1-21.  https://doi.org/10.1016/j.neuron.2023.08.017
  29. Pavlov VA, Tracey KJ. Neural circuitry and immunity. Immunol Res. 2015;63(1-3):38-57.  https://doi.org/10.1007/s12026-015-8718-1
  30. Domoto R, Sekiguchi F, Tsubota M, et al. Macrophage as a Peripheral Pain Regulator. Cells. 2021;10(8):1881. https://doi.org/10.3390/cells10081881
  31. Zhivolupov SA, Damulin IV, Samartsev IN, et al. Clinical use of Neuromidin in questions and answers. SPb.: VMedA; 2014. (In Russ.).
  32. Merkulov YuA, Magomedova AM, Biglova AN, et al. Compression of nerves and senses: ipidacrine as the light at the end of the tunnel. Zhurnal Nevrologii i Psikhiatrii im. S.S. Korsakova. 2021;121(2):31-37. (In Russ.). https://doi.org/10.17116/jnevro202112102131
  33. Avakian GN, Avakian GG. A clinical-electroneuromyographic study of the efficacy of ipidacrine in patients with mononeuropathies. Zhurnal Nevrologii i Psikhiatrii im. S.S. Korsakova. 2015;115(9):17-22. (In Russ.). https://doi.org/10.17116/jnevro20151159117-22
  34. Levin OS, Matvievskaya OV. Evaluation of epidemiological data on effect of therapy with Ipigrix® on motor and sensory functions in ambulatory patients with various diseases ofperipheral nervous system. Medical Alphabet. 2019;1(2):11-14. (In Russ.). https://doi.org/10.33667/2078-5631-2019-1-2(377)-11-14
  35. Zhivolupov SA, Samartsev IN. Central mechanisms of therapeutic effectiveness of neuromidin in the treatment of peripheral nerve lesions. Zhurnal Nevrologii i Psikhiatrii im. S.S. Korsakova. 2010;110(3):25-30. (In Russ.).
  36. Strokov IA, Zinovyeva OE, Barinov AN, et al. Neuromidin in the treatment of diabetic polyneuropathy. Neur Journal. 2007;12(6):52-55. (In Russ.).
  37. Romeiko DI, Bilodid IK, Pukita IS, et al. The effectiveness of Neuromidin in the treatment of diabetic distal polyneuropathy. Meditsinskiye Novosti. 2009;6:82-85. (In Russ.).
  38. Zhivolupov SA, Vorob’eva MN, Samartsev IN, et al. Innovation in differential diagnosis and monitoring of rational therapy in patients with lumbosacral radiculopathies. Zhurnal Nevrologii i Psikhiatrii im. S.S. Korsakova. 2014;114(8):25-31. (In Russ.).
  39. Boyko AN, Batysheva TT, Zaitsev KA, et al. Primenenie preparata aksamon v kompleksnoj reabilitatsii bol’nykh s dvigatel’nymi narusheniyami pri patologii poyasnichnogo otdela pozvonochnika. Zhurnal Nevrologii i Psikhiatrii im. S.S. Korsakova. 2008;108(9):45-47. (In Russ.).
  40. Dzyak LA, Zorin NA, Kirichenko AG, et al. Results of complex treatment of patients with radiculopathy and radiculoischemia caused by pathology of the intervertebral discs of the lumbar spine, including the drug neuromidin. Ukrainian Neurosurgical Journal. 2004;4:98-101. (In Russ.).
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.