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Astasheva I.B.

Pirogov Russian National Research Medical University

Guseva M.R.

Pirogov Russian National Research Medical University

Atamuradov R.

Pirogov Russian National Research Medical University

Marenkov V.V.

Yudin City Clinical Hospital

Kyun Yu.A.

Morozov Children’s City Clinical Hospital

Lobanova E.I.

Pirogov Russian National Research Medical University

Anatomo-functional state of the central retina in premature infants with intraventricular hemorrhage and retinopathy of prematurity

Authors:

Astasheva I.B., Guseva M.R., Atamuradov R., Marenkov V.V., Kyun Yu.A., Lobanova E.I.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2024;124(1): 66‑75

DOI: 10.17116/jnevro202412401166

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To cite this article:

Astasheva IB, Guseva MR, Atamuradov R, Marenkov VV, Kyun YuA, Lobanova EI. Anatomo-functional state of the central retina in premature infants with intraventricular hemorrhage and retinopathy of prematurity. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;124(1):66‑75. (In Russ.)
https://doi.org/10.17116/jnevro202412401166

Подписка 2025 (S.S. Korsakov Journal of Neurology and Psychiatry)
 
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OBJECTIVE

Assessment of the anatomo-functional state of the central retina in children with intraventricular hemorrhage (IVH) and retinopathy of prematurity (ROP) in the long-term period.

MATERIAL AND METHODS

We examined 51 patients (102 eyes) born 25—34 weeks’ of gestation (birth weight 700—2290 g), aged 8.83±3.5 years, and 18 children (36 eyes) born prematurely aged 10.8±3.2 years. The children underwent standard ophthalmologic examination, optical coherence tomography (OCT) and visual evoked potentials (VEP).

RESULTS

Retinal thickness (RT) and retinal volume (RV) in the fovea of premature infants with PH and/or IVH are significantly higher than in healthy full-term infants, which correlates with lower visual acuity (p<0.05). RT and RV in the fovea has an inverse proportional relationship with gestational age (GA), (p<0.05). According to the results of VEP, moderate organic changes in the conduction tract of the visual analyzer are noted in 45% of premature infants (p<0.05).

CONCLUSION

The process of macula formation is affected by many perinatal and postnatal factors, namely: GA, birth weight, ROP, hypoxic-ischemic CNS diseases, and refractive disorders.

Keywords:

Intraventricular hemorrhages
retinopathy of prematurity
macula
optical coherence tomography
visual evoked potentials

Authors:

Astasheva I.B.

Pirogov Russian National Research Medical University

Guseva M.R.

Pirogov Russian National Research Medical University

Atamuradov R.

Pirogov Russian National Research Medical University

Marenkov V.V.

Yudin City Clinical Hospital

Kyun Yu.A.

Morozov Children’s City Clinical Hospital

Lobanova E.I.

Pirogov Russian National Research Medical University

Received:

23.10.2023

Accepted:

29.10.2023

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