Alternative methods of therapy for comorbid sleep disorders as a method of choice in adult patients with epilepsy

Zhidik A.G.; Kozhokaru A.B.

doi:https://doi.org/10.17116/jnevro202312308142

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OBJECTIVE

Systematization and generalization of data from domestic and foreign literature on alternative methods of treatment of sleep disorders in epilepsy.

MATERIAL AND METHODS

The search for data from domestic and foreign literary sources was carried out in the electronic databases Medline (PubMed), Scopus, Web of Science, eLibrary, CyberLeninka, Google Scholar.

RESULTS

The data of modern randomized trials, meta-analyzes on the effectiveness of various non-traditional methods as a method of choice for epilepsy with comorbid sleep disorders have been analyzed.

CONCLUSIONS

Complementary (alternative) treatments have many advantages over the classical pharmacotherapy of sleep disorders in epilepsy, in the form of non-invasiveness, low incidence of side-effects, ease of use, and lack of a dose-dependent effect. Of course, the targets of most of the above methods are not focused and not very specific, and the sample size is too small to obtain impartial and meaningful clinical conclusions, but this once again emphasizes the urgent need for large-scale clinical trials, which is necessary to develop evidence-based treatments for comorbid sleep disorders in epilepsy.

Keywords:

sleep disorders

insomnia

parasomnias

sleep breathing disorders

restless leg syndrome

sleep-dependent epilepsy

alternative treatment methods

Authors:

Zhidik A.G.

State Research Center — Burnasyan Federal Medical Biophysical Center

ORCID: 0009-0000-9789-8790

Kozhokaru A.B.

State Research Center — Burnasyan Federal Medical Biophysical Center;
Central State Medical Academy of Department of Presidential Affairs

ORCID: 0000-0001-9306-1686

Received:

14.03.2023

Accepted:

22.03.2023

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