The results of an open observational study on multimodal effects of the efficacy and safety of supplement neurouridine in patients with nonspecific low back pain (MULTINEURO-1)

Yakupov E.Z.; Troshina Y.V.; Kashapova A.O.; Nasrieva A.M.; Chizh R.S.

doi:https://doi.org/10.17116/jnevro202012009153

Yakupov E.Z.

Scientific Research Medical Complex «Your Health»;
Kazan State Medical University

Troshina Y.V.

Scientific Research Medical Complex «Your Health»;
Kazan State Medical University

Kashapova A.O.

Scientific Research Medical Complex «Your Health»

Nasrieva A.M.

Scientific Research Medical Complex «Your Health»

Chizh R.S.

Scientific Research Medical Complex «Your Health»

The results of an open observational study on multimodal effects of the efficacy and safety of supplement neurouridine in patients with nonspecific low back pain (MULTINEURO-1)

Authors:

Yakupov E.Z., Troshina Y.V., Kashapova A.O., Nasrieva A.M., Chizh R.S.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2020;120(9): 53‑59

DOI: 10.17116/jnevro202012009153

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To cite this article:

Yakupov EZ, Troshina YV, Kashapova AO, Nasrieva AM, Chizh RS. The results of an open observational study on multimodal effects of the efficacy and safety of supplement neurouridine in patients with nonspecific low back pain (MULTINEURO-1). S.S. Korsakov Journal of Neurology and Psychiatry. 2020;120(9):53‑59. (In Russ.)
https://doi.org/10.17116/jnevro202012009153

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)

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OBJECTIVE

The article presents the results of the first observational study in the Russian Federation on the efficacy and safety of high doses of uridine monophosphate (150 mg) in combination with choline (the supplement neurouridine) in the treatment of patients with nonspecific low back pain.

MATERIAL AND METHODS

The Visual Analogue scale (VAS), the painDETECT questionnaire (PD-Q), the Roland—Morris Low Back Pain and Disability Questionnaire, the Hospital Anxiety and Depression Scale (HADS) and the Pittsburgh Sleep Quality Index were used to assess the efficacy of neurouridin in 50 patients with lower back pain.

RESULTS AND CONCLUSION

A conclusion was also made about a greater decrease in the intensity of pain in the main group than in the comparison group, a positive effect of treatment on a decrease in the severity of the neuropathic component of pain was not- ed according to the results of PD-Q, revealing signs of improved functional status according to the analysis of the Roland-Morris low back pain and disability questionnaire.

Keywords:

low back pain

uridine monophosphate

neurouridine

Authors:

Yakupov E.Z.

Scientific Research Medical Complex «Your Health»;
Kazan State Medical University

Troshina Y.V.

Scientific Research Medical Complex «Your Health»;
Kazan State Medical University

Kashapova A.O.

Scientific Research Medical Complex «Your Health»

Nasrieva A.M.

Scientific Research Medical Complex «Your Health»

Chizh R.S.

Scientific Research Medical Complex «Your Health»

Received:

30.07.2020

Accepted:

10.08.2020

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References:

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