The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-4329
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2026
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Kaleda V.G.

Nauchnyĭ tsentr psikhicheskogo zdorov'ia RAMN, Moskva

Zyablov V.A.

Mental Health Research Centre, Moscow, Russia

Continuous cycling bipolar affective disorders in youth

Authors:

Kaleda V.G., Zyablov V.A.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2020;120(4): 14‑22

DOI: 10.17116/jnevro202012004114

Read: 2535 times

Download PDF (RU)
Contact the author
Table of contents

CONTINUOUS CYCLING BIPOLAR AFFECTIVE DISORDERS IN YOUTH
CONTINUOUS CYCLING BIPOLAR AFFECTIVE DISORDERS IN YOUTH

To cite this article:

Kaleda VG, Zyablov VA. Continuous cycling bipolar affective disorders in youth. S.S. Korsakov Journal of Neurology and Psychiatry. 2020;120(4):14‑22. (In Russ.)
https://doi.org/10.17116/jnevro202012004114

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Recommended articles:
Comparative study of cognitive impairment in subgroups of bipo­lar affe­ctive diso­rder types I and II, occu­rring with and without psychotic symptoms. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(3):7-11
Asso­ciation of cortisol levels with psychopathological features of depression and therapeutic response in female patients. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(6):45-54
Analysis of Russian studies of suicidal beha­vior in patients with bipo­lar affe­ctive diso­rder. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(7):25-33
Digi­tal reality: Impact on the mental health of young people. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(10):12-17
Psychopathological features of obse­ssive-compulsive diso­rder with reli­gious content in young men. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(10-2):32-37
Comparative clinical and psychometric para­meters of pathological gambling and Inte­rnet addi­ctions in young patients with mental diso­rders. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(10-2):57-62
Search for neurophysiological markers of schi­zophrenia spectrum diso­rders: ocular microtremor and contrast sensitivity. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(12):228-236
Asso­ciation of hema­tological coefficients of inflammation using high-density lipo­proteins in evaluating the seve­rity of mood diso­rders. S.S. Korsakov Journal of Neurology and Psychiatry. 2026;(2):116-122
The expe­rience of the narcological service medi­cal specialists in the prevention of substance use among adolescents and youth. Russian Journal of Preventive Medi­cine. 2025;(5):62-68
Abstract:

Objective. To reveal psychopathological characteristics and core dynamic patterns of continuous cycling bipolar affective disorders in youth. Material and methods. One hundred and seven patients (62 men and 45 women), including 59 patients of the clinical group and 48 of the follow-up group, were examined. Results and conclusion. Three types of continuous cycling bipolar affective disorders in youth are described: rhythmic, dysrhythmic and pseudorhythmic. A correlation between the dynamics of affective disorders in youth and the nosological affiliation of each of the identified types of continuous cycling course was found. The results may be useful for solving differential/diagnostic, prognostic and therapeutic tasks.

Keywords:

bipolar affective disorder
youth
continuous cycling
borderline personality disorder
schizoaffective disorder

Authors:

Kaleda V.G.

Nauchnyĭ tsentr psikhicheskogo zdorov'ia RAMN, Moskva

Zyablov V.A.

Mental Health Research Centre, Moscow, Russia

Close metadata

References:

  1. Rybakov FE. Tsiklofreniya: (Krugovoi psikhoz). M.: Isd-vo tipjgrafii. A.I. Mamontova, 1914. (In Russ.).
  2. Tiganov AS. Clinical characteristics of cyclic schizophrenia in adolescence. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 1963;63:11:1695-1702.0 (In Russ.).
  3. Falret JP. La folie circulaire ou folie a formes alternes. Arch Gen Med. 1879;1:52-68.
  4. Kahlbaum K.L. Über cyklisches Irresein. Der Irrenfreund. 1882;24:145-157.
  5. Ushkalova AV, Kostyukova EG, Mosolov SN. Modern treatment of a depressive phase (review). Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. Spetsvypuski. 2012;112(11):67-76. (In Russ.).]
  6. Smulevich AB. Depression in mental and somatic diseases (4-e izd.). M.: MIA; 2015. (In Russ.).
  7. Keck P, Mintz J, McElroy S, Freeman MP, Suppes T, Frye MA, Altshuler LL, Kupka R, Nolen WA, Leverich GS, Denicoff KD, Grunze H, Duan N, Post RM. Double-Blind, Randomized, Placebo-Controlled Trials of Ethyl-Eicosapentanoate in the Treatment of Bipolar Depression and Rapid Cycling Bipolar Disorder. Biol Psychiatry. 2006;60(9):1020-1022. https://doi.org/10.1016/j.biopsych.2006.03.056
  8. Tsutsul’kovskaya MYa, Kopeiko GI, Oleichik IV, Vladimirova TV. Rol’ psikhobiologicheskikh kharakteristik yunosheskogo vozrasta v formirovanii klinicheskoi kartiny depressii i osobennostyakh terapii. Psikhiatriya. 2003;5:21-28. (In Russ.).
  9. Mazaeva NA. Nervnaya anoreksiya v podrostkovom vozraste. Rossiiskii psikhiatricheskii zhurnal. 2012;3:45-54. (In Russ.).
  10. Kaleda VG. Youth-onset schizophrenia: psychopathology, clinical presentation and therapy. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. Spetsvypuski. 2015;115(11):26-33. (In Russ.). https://doi.org/10.17116/jnevro201511511226-33
  11. Strakowski S, Adler C, Almeida J, Altshuler LL, Blumberg HP, Chang KD, DelBello MP, Frangou S, McIntosh A, Phillips ML, Sussman JE, Townsend JD. The functional neuroanatomy of bipolar disorder: a consensus model. Bipolar Disord. 2012;14(4):313-325. https://doi.org/10.1111/j.1399-5618.2012.01022.x
  12. Brukhin AE, Onegina EYu. Affective disorders in patients with anorexia nervosa and bulimia nervosa. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2011;111(1):21-26. (In Russ.).]
  13. Oleichik IV. Psychopathology, typology and nosological evaluation of juvenile endogenous depressions: a clinical and follow-up study. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2011;111(2):10-18. (In Russ.).
  14. Kopeiko GI. Mixed affective states in the juvenile age (historical aspects, current state of the problem, psychopathology). Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2011;111(10):4-11. (In Russ.).
  15. Psychiatrie: ein Lehrbuch für Studirende und Aerzte (Psychiatry: a Manual for Students and Physicians). Von Dr. Emil Kraepelin, Professor an der Universität, Heidelberg. Leipzig: Barth, 1899, 2 vols. Price, vol. i, 9 marks; vol. ii, 15 marks. Journal of Mental Science. 1899;45(190):581-583. https://doi.org/10.1192/bjp.45.190.581
  16. Kaufman J, Birmaher B, Brent D, Rao U, Flynn C, Moreci P, Williamson D, Ryan N. Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL): Initial Reliability and Validity Data. Journal of the American Academy of Child & Adolescent Psychiatry. 1997;36(7):980-988. https://doi.org/10.1097/00004583-199707000-00021
  17. MacKinnon D, Pies R. Affective instability as rapid cycling: theoretical and clinical implications for borderline personality and bipolar spectrum disorders. Bipolar Disord. 2006;8(1):1-14. https://doi.org/10.1111/j.1399-5618.2006.00283.x
  18. Merikangas K, He J, Burstein M, Swanson SA, Avenevoli S, Cui L, Benjet C, Georgiades K, Swendsen J. Lifetime Prevalence of Mental Disorders in U.S. Adolescents: Results from the National Comorbidity Survey Replication–Adolescent Supplement (NCS-A). Journal of the American Academy of Child & Adolescent Psychiatry. 2010;49(10):980-989. https://doi.org/10.1016/j.jaac.2010.05.017
  19. Hassan A, Agha S, Langley K, Thapar A. Prevalence of bipolar disorder in children and adolescents with attention-deficit hyperactivity disorder. British Journal of Psychiatry. 2011;198(3):195-198. https://doi.org/10.1192/bjp.bp.110.078741
  20. Cardoso T, Mondin T, Souza L, da Silva RA, Magalhães PV, Kapczinski F, Jansen K. Functioning in bipolar disorder with substance abuse/dependence in a community sample of young adults. J Affect Disord. 2015;187:179-182. https://doi.org/10.1016/j.jad.2015.08.046
  21. Lichko AE. Podrostkovaya psikhiatriya: Rukovodstvo dlya vrachei. 2-e izd., dopolnennoe i pererabotannoe. L.: Meditsina; 1985. (In Russ.).
  22. Tiganov AS. Age-related aspects of depressive states. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. Spetsvypuski. 2013;113(11):3-6. (In Russ.).
  23. Morosini P, Magliano L, Brambilla L, Ugolini S, Pioli R. Development, reliability and acceptability of a new version of the DSM-IV Social and Occupational Functioning Assessment Scale (SOFAS) to assess routine social funtioning. Acta Psychiatr Scand. 2000;101(4):323-329. https://doi.org/10.1034/j.1600-0447.2000.101004323.x
  24. Kaleda VG. Zakonomernosti techeniya i iskhoda pristupoobraznykh endogennykh psikhozov, manifestiruyushchikh v yunosheskom vozraste (katamnesticheskoe issledovanie). Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2008;108(9):11-23. (In Russ.).
  25. Rumyantsev AO, Omelchenko MA, Kaleda VG. Attenuated psychotic symptoms in the structure of youth depression (clinical and psychopathological aspects). Rossyiskyi nevrologicheskii zhurnal. 2018;1:61-70. (In Russ.).
  26. Aiken C, Weisler R, Sachs G. The Bipolarity index: a clinician-rated measure of diagnostic confidence. J Affect Disord. 2015;177:59-64. https://doi.org/10.1016/j.jad.2015.02.004
  27. Gibadulin ESh. Tipologiya endogennykh manii yunosheskogo vozrasta i ee prognosticheskoe znachenie. Sotsial’naya i klinicheskaya psikhiatriya. 1992;3:30-36. (In Russ.).
  28. Lobban F, Taylor K, Murray C, Jones S. Bipolar Disorder is a two-edged sword: A qualitative study to understand the positive edge. J Affect Disord. 2012;141(2-3):204-212. https://doi.org/10.1016/j.jad.2012.03.001
  29. Dunner D, Patrick V, Fieve R. Rapid cycling manic depressive patients. Compr Psychiatry. 1977;18(6):561-566. https://doi.org/10.1016/s0010-440x(97)90006-7
  30. Papolos D, Veit S, Faedda G, Saito T, Lachman H. Ultra-ultra rapid cycling bipolar disorder is associated with the low activity catecholamine-O-methyltransferase allele. Mol Psychiatry. 1998;3(4):346-349. https://doi.org/10.1038/sj.mp.4000410
  31. Kaleda VG. Youth-onset schizophrenia: psychopathology, clinical presentation and therapy. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. Spetsvypuski. 2015;115(11):26-33. (In Russ.). https://doi.org/10.17116/jnevro201511511226-33
  32. Anufriev AK. Psikhopatologiya nachal’nykh proyavlenii bredoobrazovaniya. Nezavisimaya psikhiatriya. 1992;1-2:14-24. (In Russ.).
  33. Rihmer Z, Pestality P. Bipolar II disorder and suicidal behavior. Psychiatric Clinics of North America. 1999;22(3):667-673. https://doi.org/10.1016/s0193-953x(05)70101-5
  34. Turvey C, Coryell W, Solomon D, Leon AC, Endicott J, Kelle MB, Akiskal H. Long-term prognosis of bipolar I disorder. Acta Psychiatr Scand. 1999;99(2):110-119. https://doi.org/10.1111/j.1600-0447.1999.tb07208.x
  35. Keller M. Differential outcome of pure manic, mixed/cycling, and pure depressive episodes in patients with bipolar illness. JAMA: The Journal of the American Medical Association. 1986;255(22):3138-3142. https://doi.org/10.1001/jama.255.22.3138
  36. Perugi G, Fornaro M, Akiskal H. Are atypical depression, borderline personality disorder and bipolar II disorder overlapping manifestations of a common cyclothymic diathesis? World Psychiatry. 2011;10(1):45-51. https://doi.org/10.1002/j.2051-5545.2011.tb00013.x
  37. Üçok A, Karaveli D, Kundakçi T, Yazici O. Comorbidity of personality disorders with bipolar mood disorders. Compr Psychiatry. 1998;39(2):72-74. https://doi.org/10.1016/s0010-440x(98)90081-5
  38. Chanen A, Berk M, Thompson K. Integrating Early Intervention for Borderline Personality Disorder and Mood Disorders. Harv Rev Psychiatry. 2016;24(5):330-341. https://doi.org/10.1097/hrp.0000000000000105
  39. Bayes A, McClure G, Fletcher K, Román Ruiz Del Moral YE, Hadzi-Pavlovic D, Stevenson JL, Manicavasagar VL, Parker GB. Differentiating the bipolar disorders from borderline personality disorder. Acta Psychiatr Scand. 2015;133(3):187-195. https://doi.org/10.1111/acps.12509
  40. Grilo C, McGlashan T, Skodol A. Stability and course of personality disorders: the need to consider comorbidities and continuities between axis I psychiatric disorders and axis II personality disorders. Psychiatric Quarterly. 2000;71(4):291-307. https://doi.org/10.1023/a:1004680122613
  41. Gunderson J. Ten-Year Course of Borderline Personality Disorder. Arch Gen Psychiatry. 2011;68(8):827. https://doi.org/10.1001/archgenpsychiatry.2011.37
  42. Simutkin GG, Yakovleva AL, Bokhan NA. Problema komorbidnosti affektivnykh rasstroistv i rasstroistv lichnosti. Sotsial’naya i klinicheskaya psikhiatriya. 2014;24:2:92-98. (In Russ.).
  43. Benedetti F, Riccaboni R, Locatelli C, Poletti S, Dallaspezia S, Colombo C. Rapid Treatment Response of Suicidal Symptoms to Lithium, Sleep Deprivation, and Light Therapy (Chronotherapeutics) in Drug-Resistant Bipolar Depression. J Clin Psychiatry. 2013;75(02):133-140. https://doi.org/10.4088/jcp.13m08455
  44. Altamura A, Dell’Osso B, Berlin H, Buoli M, Bassetti R, Mundo E. Duration of untreated illness and suicide in bipolar disorder: a naturalistic study. Eur Arch Psychiatry Clin Neurosci. 2009;260(5):385-391. https://doi.org/10.1007/s00406-009-0085-2
  45. Coryell W, Solomon D, Turvey C, Keller M, Leon AC, Endicott J, Schettler P, Judd L, Mueller T. The Long-term Course of Rapid-Cycling Bipolar Disorder. Arch Gen Psychiatry. 2003;60(9):914. https://doi.org/10.1001/archpsyc.60.9.914
  46. Schneck C. Phenomenology of Rapid-Cycling Bipolar Disorder: Data From the First 500 Participants in the Systematic Treatment Enhancement Program. American Journal of Psychiatry. 2004;161(10):1902-1908. https://doi.org/10.1176/appi.ajp.161.10.1902
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.