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Gultyaeva V.V.

Research Institute of Physiology and Basic Medicine, Novosibirsk, Russia

Zinchenko M.I.

Research Institute of Physiology and Basic Medicine, Novosibirsk, Russia

Uryumtsev D.Y.

Research Institute of Physiology and Basic Medicine, Novosibirsk, Russia

Krivoschekov S.G.

Research Institute of Physiology and Basic Medicine, Novosibirsk, Russia

Aftanas L.I.

Research Institute of Physiology and Basic Medicine, Novosibirsk, Russia

Exercise for depression treatment. Exercise modalities and types

Authors:

Gultyaeva V.V., Zinchenko M.I., Uryumtsev D.Y., Krivoschekov S.G., Aftanas L.I.

More about the authors

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To cite this article:

Gultyaeva VV, Zinchenko MI, Uryumtsev DY, Krivoschekov SG, Aftanas LI. Exercise for depression treatment. Exercise modalities and types. S.S. Korsakov Journal of Neurology and Psychiatry. 2019;119(9):136‑142. (In Russ.)
https://doi.org/10.17116/jnevro2019119091136

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References:

  1. Depression. Bulletin of the World Health Organization. 2018. Accessed 20.11.18. (In Russ.). http://www.who.int/ru/news-room/fact-sheets/detail/depression
  2. Burcusa SL, Iacono WG. Risk for recurrence in depression. Clin Psychol Rev. 2007;27(8):959-985. https://doi.org/10.1016/j.cpr.2007.02.005
  3. Holzel L, Harter M, Reese C, Kriston L. Risk factors for chronic depression — a systematic review. J Affect Disord. 2011;129(1-3):1-13. https://doi.org/10.1016/j.jad.2010.03.025
  4. Petrunko OV. Chronic depressive disorders. Acta Biomedica Scientifica. 2017;2(2):114-119. (In Russ.) https://doi.org/10.7868/S1027813317020091
  5. Vancampfort D, Correll CU, Galling B, Probst M, De Hert M, Ward PB, Rosenbaum S, Gaughran F, Lally J, Stubbs B. Diabetes mellitus in people with schizophrenia, bipolar disorder and major depressive disorder: a systematic review and large scale meta-analysis. World Psychiatry. 2016;15(2):166-174. https://doi.org/10.1002/wps.20309
  6. Vancampfort D, Stubbs B, Mitchell AJ, De Hert M, Wampers M, Ward PB, Rosenbaum S, Correll CU. Risk of metabolic syndrome and its components in people with schizophrenia and related psychotic disorders, bipolar disorder and major depressive disorder: a systematic review and meta-analysis. World Psychiatry. 2015;14(3):339-347. https://doi.org/10.1002/wps.20252
  7. Vancampfort D, Mitchell AJ, De Hert M, Sienaert P, Probst M, Buys R, Stubbs B. Type 2 Diabetes in Patients with Major Depressive Disorder: A Meta-Analysis of Prevalence Estimates and Predictors. Depress Anxiety. 2015;32(10):763-773. https://doi.org/10.1002/da.22387
  8. Penninx BW. Depression and cardiovascular disease: Epidemiological evidence on their linking mechanisms. Neurosci Biobehav Rev. 2017;74(Pt B):277-286. https://doi.org/10.1016/j.neubiorev.2016.07.003
  9. Walker ER, McGee RE, Druss BG. Mortality in mental disorders and global disease burden implications: a systematic review and meta-analysis. JAMA Psychiatry. 2015;72(4):334-341. https://doi.org/10.1001/jamapsychiatry.2014.2502
  10. Ravindran L, Kennedy SH. Are antidepressants as effective as claimed? Yes, but. Can J Psychiatry. 2007;52(2):98-99; discussion 100-101. https://doi.org/10.1177/070674370705200205
  11. Bauer M, Pfennig A, Severus E, Whybrow PC, Angst J, Moller HJ. World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of unipolar depressive disorders, part 1: update 2013 on the acute and continuation treatment of unipolar depressive disorders. World J Biol Psychiatry. 2013;14(5):334-385. https://doi.org/10.3109/15622975.2013.804195
  12. Brusov OS, Panteleeva GP, Bondar’ VV, Dikaia VI, Faktor MI, Zlobina GP, Pavlova OA, Abrosimov NV, Lideman RR. A clinico-biological study of the thrombocyte serotonin-transport complex in therapeutically resistant patients with endogenous depression undergoing combined treatment. Psychiatry. 2010;6(48):71-75. (In Russ.)
  13. Lyubov EB, Sarkisyan GR. Depressive disorders: pharmacoepidemiological and clinical-economic aspects. Social and Clinical Psychiatry. 2006;16(2):93-100. (In Russ.)
  14. Pugovkina OD, Kholmogorova AB, Tzukarzi EE. Depression and resistance. Zhurnal Nevrologii i Psihiatrii im. S.S. Korsakova. 2006;16(2):47-51. (In Russ.)
  15. Bykov YuV. Therapy resistant depressions. Stavropol: Idea+; 2009. (In Russ.)
  16. Hengartner MP. Methodological flaws, conflicts of interest, and scientific fallacies: implications for the evaluation of antidepressants’ efficacy and harm. Front Psychiatry. 2017;8:275. https://doi.org/10.3389/fpsyt.2017.00275
  17. Pedersen BK, Saltin B. Exercise as medicine — evidence for prescribing exercise as therapy in 26 different chronic diseases. Scand J Med Sci Sports. 2015;25(suppl 3):1-72. https://doi.org/10.1111/sms.12581
  18. Pemberton R, Fuller Tyszkiewicz MD. Factors contributing to depressive mood states in everyday life: A systematic review. J Affect Disord. 2016;200:103-110. https://doi.org/10.1016/j.jad.2016.04.023
  19. Siqueira CC, Valiengo LL, Carvalho AF, Santos-Silva PR, Missio G, de Sousa RT, Di Natale G, Gattaz WF, Moreno RA, Machado-Vieira R. Antidepressant efficacy of adjunctive aerobic activity and associated biomarkers in major depression: a 4-week, randomized, single-blind, controlled clinical trial. PLoS One. 2016;11(5):e0154195. https://doi.org/10.1371/journal.pone.0154195
  20. Krogh J, Saltin B, Gluud C, Nordentoft M. The DEMO trial: a randomized, parallel-group, observer-blinded clinical trial of strength versus aerobic versus relaxation training for patients with mild to moderate depression. J Clin Psychiatry. 2009;70(6):790-800. https://doi.org/10.4088/JCP.08m04241
  21. Hearing CM, Chang WC, Szuhany KL, Deckersbach T, Nierenberg AA, Sylvia LG. Physical exercise for treatment of mood disorders: a critical review. Curr Behav Neurosci Rep. 2016;3(4):350-359. https://doi.org/10.1007/s40473-016-0089-y
  22. Galper DI, Trivedi MH, Barlow CE, Dunn AL, Kampert JB. Inverse association between physical inactivity and mental health in men and women. Med Sci Sports Exerc. 2006;38(1):173-178. https://doi.org/10.1249/01.mss.0000180883.32116.28
  23. Tolmunen T, Laukkanen JA, Hintikka J, Kurl S, Viinamäki H, Salonen R, Kauhanen J, Kaplan GA, Salonen JT. Low maximal oxygen uptake is associated with elevated depressive symptoms in middle-aged men. European Journal of Epidemiology. 2006;21(9):701-706. https://doi.org/10.1007/s10654-006-9038-5
  24. Stubbs B, Vancampfort D, Firth J, Schuch FB, Hallgren M, Smith L, Gardner B, Kahl KG, Veronese N, Solmi M, Carvalho AF, Koyanagi A. Relationship between sedentary behavior and depression: A mediation analysis of influential factors across the lifespan among 42,469 people in low- and middle-income countries. J Affect Disord. 2018;229:231-238. https://doi.org/10.1016/j.jad.2017.12.104
  25. Sui X, Laditka JN, Church TS, Hardin JW, Chase N, Davis K, Blair SN. Prospective study of cardiorespiratory fitness and depressive symptoms in women and men. J Psychiatr Res. 2009;43(5):546-552. https://doi.org/10.1016/j.jpsychires.2008.08.002
  26. Becofsky KM, Sui X, Lee DC, Wilcox S, Zhang J, Blair SN. A prospective study of fitness, fatness, and depressive symptoms. Am J Epidemiol. 2015;181(5):311-320. https://doi.org/10.1093/aje/kwu330
  27. Schuch FB, Vancampfort D, Firth J, Rosenbaum S, Ward PB, Silva ES, Hallgren M, Ponce De Leon A, Dunn AL, Deslandes AC, Fleck MP, Carvalho AF, Stubbs B. Physical activity and incident depression: a meta-analysis of prospective cohort studies. Am J Psychiatry. 2018:appiajp201817111194. https://doi.org/10.1176/appi.ajp.2018.17111194
  28. Rethorst CD, Wipfli BM, Landers DM. The antidepressive effects of exercise: a meta-analysis of randomized trials. Sports Med. 2009;39(6):491-511. https://doi.org/10.2165/00007256-200939060-00004
  29. Cooney GM, Dwan K, Greig CA, Lawlor DA, Rimer J, Waugh FR, McMurdo M, Mead GE. Exercise for depression. Cochrane Database Syst Rev. 2013(9):CD004366. https://doi.org/10.1002/14651858.CD004366.pub6
  30. Josefsson T, Lindwall M, Archer T. Physical exercise intervention in depressive disorders: meta-analysis and systematic review. Scand J Med Sci Sports. 2014;24(2):259-272. https://doi.org/10.1111/sms.12050
  31. Heinzel S, Lawrence JB, Kallies G, Rapp MA, Heissel A. Using exercise to fight depression in older adults a systematic review and meta-analysis. Geropsych-the Journal of Gerontopsychology and Geriatric Psychiatry. 2015;28(4):149-162. https://doi.org/10.1024/1662-9647/a000133
  32. Kvam S, Kleppe CL, Nordhus IH, Hovland A. Exercise as a treatment for depression: A meta-analysis. J Affect Disord. 2016;202:67-86. https://doi.org/10.1016/j.jad.2016.03.063
  33. Schuch FB, Vancampfort D, Richards J, Rosenbaum S, Ward PB, Stubbs B. Exercise as a treatment for depression: A meta-analysis adjusting for publication bias. J Psychiatr Res. 2016;77:42-51. https://doi.org/10.1016/j.jpsychires.2016.02.023
  34. Gourgouvelis J, Yielder P, Clarke ST, Behbahani H, Murphy BA. Exercise leads to better clinical outcomes in those receiving medication plus cognitive behavioral therapy for major depressive disorder. Front Psychiatry. 2018;9:37. https://doi.org/10.3389/fpsyt.2018.00037
  35. Hallgren M, Vancampfort D, Stubbs B. Exercise is medicine for depression: even when the «pill» is small. Neuropsychiatr Dis Treat. 2016;12:2715-2721. https://doi.org/10.2147/NDT.S121782
  36. Fiuza-Luces C, Garatachea N, Berger NA, Lucia A. Exercise is the real polypill. Physiology (Bethesda). 2013;28(5):330-358. https://doi.org/10.1152/physiol.00019.2013
  37. Huh JY. The role of exercise-induced myokines in regulating metabolism. Arch Pharm Res. 2018;41(1):14-29. https://doi.org/10.1007/s12272-017-0994-y
  38. Hasegawa N, Fujie S, Horii N, Miyamoto-Mikami E, Tsuji K, Uchida M, Hamaoka T, Tabata I, Iemitsu M. Effects of different exercise modes on arterial stiffness and nitric oxide synthesis. Med Sci Sports Exerc. 2018;50(6):1177-1185. https://doi.org/10.1249/MSS.0000000000001567
  39. Garber CE, Blissmer B, Deschenes MR, Franklin BA, Lamonte MJ, Lee IM, Nieman DC, Swain DP. American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise. Med Sci Sports Exerc. 2011;43(7):1334-1359. https://doi.org/10.1249/MSS.0b013e318213fefb
  40. Gultyaeva VV, Zinchenko MI, Uryumtsev DYu, Grishin VG, Grishin OV. Physical activity and arterial blood pressure response to handgrip exercise. Fiziologiya Cheloveka. 2019;45(1):73—80. (In Russ.) https://doi.org/10.1134/S0131164618050041
  41. Borg E, Kaijser L. A comparison between three rating scales for perceived exertion and two different work tests. Scand J Med Sci Sports. 2006;16(1):57-69. https://doi.org/10.1111/j.1600-0838.2005.00448.x
  42. Spielholz P. Calibrating Borg scale ratings of hand force exertion. Appl Ergon. 2006;37(5):615-618. https://doi.org/10.1016/j.apergo.2005.10.001
  43. Li KW, Yu R. Assessment of grip force and subjective hand force exertion under handedness and postural conditions. Appl Ergon. 2011;42(6):929-933. https://doi.org/10.1016/j.apergo.2011.03.001
  44. Buchholz B, Park JS, Gold JE, Punnett L. Subjective ratings of upper extremity exposures: inter-method agreement with direct measurement of exposures. Ergonomics. 2008;51(7):1064-1077. https://doi.org/10.1080/00140130801915220
  45. Meyer JD, Koltyn KF, Stegner AJ, Kim JS, Cook DB. Influence of exercise intensity for improving depressed mood in depression: a dose-response study. Behav Ther. 2016;47(4):527-537. https://doi.org/10.1016/j.beth.2016.04.003
  46. Dunn AL, Trivedi MH, Kampert JB, Clark CG, Chambliss HO. Exercise treatment for depression: efficacy and dose response. Am J Prev Med. 2005;28(1):1-8. https://doi.org/10.1016/j.amepre.2004.09.003
  47. Balchin R, Linde J, Blackhurst D, Rauch HL, Schonbachler G. Sweating away depression? The impact of intensive exercise on depression. J Affect Disord. 2016;200:218-221. https://doi.org/10.1016/j.jad.2016.04.030
  48. Helgadottir B, Hallgren M, Ekblom O, Forsell Y. Training fast or slow? Exercise for depression: A randomized controlled trial. Prev Med. 2016;91:123-131. https://doi.org/10.1016/j.ypmed.2016.08.011
  49. Helgadottir B, Forsell Y, Hallgren M, Moller J, Ekblom O. Long-term effects of exercise at different intensity levels on depression: A randomized controlled trial. Preventive Medicine. 2017;105:37-46. https://doi.org/10.1016/j.ypmed.2017.08.008
  50. Hanssen H, Minghetti A, Faude O, Schmidt-Trucksass A, Zahner L, Beck J, Donath L. Effects of endurance exercise modalities on arterial stiffness in patients suffering from unipolar depression: a randomized controlled trial. Front Psychiatry. 2017;8:311. https://doi.org/10.3389/fpsyt.2017.00311
  51. Hallgren M, Kraepelien M, Ojehagen A, Lindefors N, Zeebari Z, Kaldo V, Forsell Y. Physical exercise and internet-based cognitive-behavioural therapy in the treatment of depression: randomised controlled trial. Br J Psychiatry. 2015;207(3):227-234. https://doi.org/10.1192/bjp.bp.114.160101
  52. Hallgren M, Helgadottir B, Herring MP, Zeebari Z, Lindefors N, Kaldo V, Ojehagen A, Forsell Y. Exercise and internet-based cognitive-behavioural therapy for depression: multicentre randomised controlled trial with 12-month follow-up. Br J Psychiatry. 2016;209(5):414-420. https://doi.org/10.1192/bjp.bp.115.177576
  53. Heinzel S, Rapp MA, Fydrich T, Strohle A, Teran C, Kallies G, Schwefel M, Heissel A. neurobiological mechanisms of exercise and psychotherapy in depression: the SPeED study-rationale, design, and methodological issues. Clin Trials. 2018;15(1):53-64. https://doi.org/10.1177/1740774517729161
  54. Perraton LG, Kumar S, Machotka Z. Exercise parameters in the treatment of clinical depression: a systematic review of randomized controlled trials. J Eval Clin Pract. 2010;16(3):597-604. https://doi.org/10.1111/j.1365-2753.2009.01188.x
  55. Stanton R, Reaburn P. Exercise and the treatment of depression: a review of the exercise program variables. J Sci Med Sport. 2014;17(2):177-182. https://doi.org/10.1016/j.jsams.2013.03.010
  56. Mead GE, Morley W, Campbell P, Greig CA, McMurdo M, Lawlor DA. Exercise for depression. Cochrane Database Syst Rev. 2009(3):CD004366. https://doi.org/10.1002/14651858.CD004366.pub4
  57. Rimer J, Dwan K, Lawlor DA, Greig CA, McMurdo M, Morley W, Mead GE. Exercise for depression. Cochrane Database Syst Rev. 2012(7):CD004366. https://doi.org/10.1002/14651858.CD004366.pub5
  58. Stanton R, Reaburn P, Happell B. Is cardiovascular or resistance exercise better to treat patients with depression? A narrative review. Issues Ment Health Nurs. 2013;34(7):531-538. https://doi.org/10.3109/01612840.2013.774077
  59. Salehi I, Hosseini SM, Haghighi M, Jahangard L, Bajoghli H, Gerber M, Puhse U, Kirov R, Holsboer-Trachsler E, Brand S. Electroconvulsive therapy and aerobic exercise training increased BDNF and ameliorated depressive symptoms in patients suffering from treatment-resistant major depressive disorder. J Psychiatr Res. 2014;57:117-124. https://doi.org/10.1016/j.jpsychires.2014.06.018
  60. Meyer JD, Ellingson LD, Koltyn KF, Stegner AJ, Kim JS, Cook DB. Psychobiological responses to preferred and prescribed intensity exercise in major depressive disorder. Med Sci Sports Exerc. 2016;48(11):2207-2215. https://doi.org/10.1249/MSS.0000000000001022
  61. Dinoff A, Herrmann N, Swardfager W, Liu CS, Sherman C, Chan S, Lanctot KL. The effect of exercise training on resting concentrations of peripheral brain-derived neurotrophic factor (BDNF): A Meta-Analysis. PLoS One. 2016;11(9):e0163037. https://doi.org/10.1371/journal.pone.0163037
  62. Muller P, Rehfeld K, Schmicker M, Hokelmann A, Dordevic M, Lessmann V, Brigadski T, Kaufmann J, Muller NG. Evolution of neuroplasticity in response to physical activity in old age: the case for dancing. Front Aging Neurosci. 2017;9:56. https://doi.org/10.3389/fnagi.2017.00056
  63. Wang CW, Chan CH, Ho RT, Chan JS, Ng SM, Chan CL. Managing stress and anxiety through qigong exercise in healthy adults: a systematic review and meta-analysis of randomized controlled trials. BMC Complement Altern Med. 2014;14:8. https://doi.org/10.1186/1472-6882-14-8
  64. Zou L, Yeung A, Quan X, Hui SS, Hu X, Chan JSM, Wang C, Boyden SD, Sun L, Wang H. Mindfulness-Based Baduanjin Exercise for Depression and Anxiety in People with Physical or Mental Illnesses: A Systematic Review and Meta-Analysis. Int J Environ Res Public Health. 2018;15(2). https://doi.org/10.3390/ijerph15020321
  65. Prathikanti S, Rivera R, Cochran A, Tungol JG, Fayazmanesh N, Weinmann E. Treating major depression with yoga: A prospective, randomized, controlled pilot trial. PLoS One. 2017;12(3):e0173869. https://doi.org/10.1371/journal.pone.0173869
  66. Streeter CC, Gerbarg PL, Whitfield TH, Owen L, Johnston J, Silveri MM, Gensler M, Faulkner CL, Mann C, Wixted M, Hernon AM, Nyer MB, Brown ERP, Jensen JE. Treatment of major depressive disorder with iyengar yoga and coherent breathing: a randomized controlled dosing study. J Altern Complement Med. 2017;23(3):201-207. https://doi.org/10.1089/acm.2016.0140
  67. Brand S, Colledge F, Ludyga S, Emmenegger R, Kalak N, Sadeghi Bahmani D, Holsboer-Trachsler E, Pühse U, Gerber M. Acute bouts of exercising improved mood, rumination and social interaction in inpatients with mental disorders. Front Psychol. 2018;9:249. https://doi.org/10.3389/fpsyg.2018.00249
  68. Meyer JD, Koltyn KF, Stegner AJ, Kim JS, Cook DB. Relationships between serum BDNF and the antidepressant effect of acute exercise in depressed women. Psychoneuroendocrinology. 2016;74:286-294. https://doi.org/10.1016/j.psyneuen.2016.09.022
  69. Basso JC, Suzuki WA. The effects of acute exercise on mood, cognition, neurophysiology, and neurochemical pathways: a review. Brain Plast. 2017;2(2):127-152. https://doi.org/10.3233/BPL-160040
  70. Dinoff A, Herrmann N, Swardfager W, Lanctot KL. The effect of acute exercise on blood concentrations of brain-derived neurotrophic factor in healthy adults: a meta-analysis. Eur J Neurosci. 2017;46(1):1635-1646. https://doi.org/10.1111/ejn.13603
  71. Osei-Tutu KB, Campagna PD. The effects of short- vs. long-bout exercise on mood, VO2max, and percent body fat. Prev Med. 2005;40(1):92-98. https://doi.org/10.1016/j.ypmed.2004.05.005
  72. Gerber M, Holsboer-Trachsler E, Puhse U, Brand S. Exercise is medicine for patients with major depressive disorders: but only if the «pill» is taken! Neuropsychiatr Dis Treat. 2016;12:1977-1981. https://doi.org/10.2147/NDT.S110656
  73. Hallgren M, Stubbs B, Vancampfort D, Lundin A, Jaakallio P, Forsell Y. Treatment guidelines for depression: greater emphasis on physical activity is needed. Eur Psychiatry. 2017;40:1-3. https://doi.org/10.1016/j.eurpsy.2016.08.011

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