Arterial hypertension, cognitive disorders and dementia: a view of a cardiologist

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This article presents a review of Russian and foreign literature about the impact of arterial hypertension (AH) on the risk of cognitive impairment and dementia. Large studies have demonstrated the effect of blood pressure (BP) on the risk of vascular dementia and Alzheimer’s disease (AD) in elderly and oldest old people as well as a role of antihypertensive therapy. There is evidence of a negative effect of hypertension in middle age on cognitive functions in late-life. Observational studies as a whole have shown the positive effect of antihypertensive therapy on the prevention of cognitive function and dementia. However, there are a number of limitations that dictate the need for further research on this issue. The importance of the interdisciplinary approach to treatment of cognitive impairment by cardiologists and/or therapists, together with neurologists, as well as complex treatment regimens, including correction of risk factors and neuroprotective therapy, is highlighted.

Keywords:

arterial hypertension

cognitive impairment

dementia

Alzheimer disease

antihypertensive therapy

Authors:

Ostroumova O.D.

Kafedra fakul'tetskoĭ terapii i professional'nykh bolezneĭ Moskovskogo gosudarstvennogo mediko-stomatologicheskogo universiteta im. A.I. Evdokimova, Moskva

SPIN RSCI: 3910-6585
Scopus AuthorID: 7004067629
ResearcherID: M-9553-2014
ORCID: 0000-0002-0795-8225

Cherniaeva M.S.

Central State Medical Academy of Department of Presidential Affairs, Moscow, Russia

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