The problem of aggressive behavior in epilepsy: clinical and neurobiological aspects

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Aggressive behavior is observed in a significant number of patients with epilepsy. The aggressive behavior is associated with structural and functional changes in the amygdala, orbitofrontal cortex and striatum. From the clinical point of view, aggressive behavior more often is not related to the seizure, and develops as part of borderline psychiatric disorder. Another potential cause of aggressive behavior is postictal psychotic disorder. Pre- and intraictal aggressive behavior is rarely observed. Anticonvulsants may influence differently on aggression. Antidepressants, neuroleptics, normotimics and psychotherapy are used in correction of aggression.

Keywords:

epilepsy

aggressive behavior

depression

psychosis

personality disorders

Authors:

Kutlubaev M.A.

Nevrologicheskoe otdelenie Respublikanskoĭ klinicheskoĭ bol'nitsy im. G.G. Kuvatova

SPIN RSCI: 4713-0312
Scopus AuthorID: 9241930700
ORCID: 0000-0003-1001-2024

Mendelevich V.D.

Kazanskiĭ gosudarstvennyĭ meditsinskiĭ universitet

SPIN RSCI: 2302-2590
Scopus AuthorID: 6602765981
ResearcherID: O-4908-2016
ORCID: 0000-0001-8489-3130

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