Risk factors and prevention of recurrent dynamics of depression

Vel'tishchev D.Iu.; Kovalevskaia O.B.; Seravina O.F.

doi:https://doi.org/10.17116/jnevro201711761120-125

Close metadata

Recommended articles:

Structural and functional features of the main arteries of the brain and tumor necrosis factor-alpha in people with chronic non-infectious diseases. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(11):178-184

Analysis of medical preventive structures staff resources in 2023. Russian Journal of Preventive Medicine. 2024;(10):45-51

Risk factors associated with myopic maculopathy in acquired myopia. Russian Annals of Ophthalmology. 2024;(5):35-45

Predictors of atrial fibrillation recurrence after biatrial cryo-maze procedure: a systematic review. Pirogov Russian Journal of Surgery. 2024;(11):100-104

Rationale for the use of non-linear statistical methods in the analysis of relationships between risk factors and fatal events according to the data of long-term prospective observation in population of Russia and the United States of America. Russian Journal of Preventive Medicine. 2024;(11):34-39

Features of comorbidity pathology in young people. Russian Journal of Preventive Medicine. 2024;(11):63-69

Proton pump inhibitors: positive and negative properties. On the 45th anniversary of their discovery. Russian Journal of Preventive Medicine. 2024;(11):135-140

Antidepressants as additional drugs for human brain gliomas. Burdenko's Journal of Neurosurgery. 2024;(6):97-102

Comparison of models for prediction of spontaneous preterm birth. Medical Technologies. Assessment and Choice. 2024;(4):10-19

Predictors of aortic valve dysfunction after the Ozaki procedure. Russian Journal of Cardiology and Cardiovascular Surgery. 2024;(6):624-628

Abstract:

The existing literature in the field demonstrates that in the majority of cases depressive disorder has a recurrent course that resulted in negative consequences: an increase in a number of chronic and marked episodes, a higher risk of suicide and stable cognitive deficit. An analysis of predictors promoting the formation of recurrent depressive disorder allows an identification of a constellation of biological, psychological, therapeutic, social factors which should be taken into account in the choice of methods of prevention of the next episode of depression. Currently, the prolonged supporting psychopharmacotherapy, including antidepressant therapy, is a main tactics in the prevention of recurrent dynamics of depressive disorder though its efficacy is understudied.

Keywords:

recurrent depression

risk factors

predictors

prevention

psychopharmacotherapy

antidepressants

sertraline

Authors:

Vel'tishchev D.Iu.

Moskovskiĭ NII psikhiatrii

Kovalevskaia O.B.

Moskovskiĭ nauchno-issledovatel'skiĭ institut psikhiatrii Minzdrava Rossii, Moskva

Seravina O.F.

Moskovskiĭ nauchno-issledovatel'skiĭ institut psikhiatrii Minzdrava Rossii, Moskva

Close metadata

References:

Angst J. The course of affective disorders. Psychopathol. 1986;19(suppl 2): 47-52.
Solomon DA, Keller MB, Leon AC, Mueller TI, Lavory PV. Multiple recurrences of major depression. Amer J Psychiatr. 2000;157:229-233.
Burcusa S, Iacono W. Risk for recurrence in depression. Clin Psychol Rev. 2007;27:8:959-985.
Monroe SM, Harkness KL. Recurrence in major depression: a conceptual analysis. Psychol Rev. 2011;118:4:655-674.
Bauer M, Severus E, Kohler S, Whybrow P, Angst J, Mueller H. World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for biological treatment of unipolar depressive disorders. Part 2: Maintenance treatment of major depressive disorder — Update 2015. World J Biol Psychiatr. 2015;16:76-95.
Kessler RC, McGonagle KA, Zhao S, Nelson CB, Hughes M, Eshleman S, Wittchen HU, Kendler KS. Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Archives of General Psychiatry. 1994;51:8-19.
Harris EC, Barraclough B. Suicide as an outcome for mental disorders: A meta-analysis. British Journal of Psychiatry. 1997;170:205-228.
Lee AS. Better outcomes for depressive disorders? Psychol Med. 2003;33:769-774.
Kessing LV, Andersen PK. Evidence for clinical progression of unipolar and bipolar disorders. Acta Psychiatr Scand. 2017;135:51-64.
Kuehner C. Gender differences in unipolar depression: An update of epidemiological findings and possible explanations. Acta Psychiatrica Scandinavica. 2003;108:163-174.
Wainwright NWJ, Surtees PG. Childhood adversity, gender and depression over the life-course. Journal of Affective Disorders. 2002;72:33-44.
Kovacs M, Obrosky DS, Sherrill J. Developmental changes in the phenomenology of depression in girls compared to boys from childhood onward. Journal of Affective Disorders. 2003;74:33-48.
Kessing LV. Recurrence in affective disorder: II. Effect of age and gender. British Journal of Psychiatry. 1998;172:29-34.
Gonzales LR, Lewinsohn PM, Clarke GN. Longitudinal follow-up of unipolar depressives: An investigation of predictors to relapse. Journal of Consulting and Clinical Psychology. 1985;53(4):461-469.
Birmaher B, Arbelaez c, Brent D. Course and outcome of child and adolescent major depressive disorder. Child Adolesc Psychiatric Clin N Am. 2002;11:619-627.
Kessler RC, McGonagle KA, Swartz M, Blazer DG, Nelson CB. Sex and depression in the National Comorbidity Survey I: Lifetime prevalence, chronicity, and recurrence. Journal of Affective Disorders. 1993;29:85-96.
Lewinsohn PM, Allen NB, Seeley JR, Gotlib IH. First onset versus recurrence of depression: Differential processes of psychosocial risk. Journal of Abnormal Psychology. 1999;108(3):483-489.
Monroe SM, Roberts JE, Kupfer DJ, Frank E. Life stress and treatment course of recurrent depression: II. Postrecovery associations with attrition, symptom course, and recurrence over 3 years. Journal of Abnormal Psychology. 1996;105(3):313-328.
Harkness KL, Monroe SM, Simons AD, Thase M. The generation of life events in recurrent and non-recurrent depression. Psychological Medicine. 1999;29:135-144.
Sheeber L, Hops H, Alperty A, Davis B, Andrews J. Family support and conflict: Prospective relations to adolescent depression. Journal of Abnormal Child Psychology. 1997;25(4):333-344.
Stice E, Ragan J, Randall P. Prospective relations between social support and depression: Differential direction of effects for parent and peer support? Journal of Abnormal Psychology. 2004;113(1):115-159.
Brugha TS, Bebbington PE, Stretch DD, MacCarthy B, Wykes T. Predicting the short-term outcome of first episodes and recurrences of clinical depression: A prospective study of life events, difficulties, and social support networks. Journal of Clinical Psychiatry. 1997;58(7):298-306.
Lara ME, Leader J, Klein DN. The association between social support and course of depression: Is it confounded with personality? Journal of Abnormal Psychology. 1997;106(3):478-482.
Wilhelm K, Parker G, Dewhurst-Savellis J, Asghari A. Psychological predictors of single and recurrent major depressive episodes. Journal of Affective Disorders. 1999;54:139-147.
Lewinsohn PM, Hoberman HM, Rosenbaum M. A prospective study of risk factors for unipolar depression. Journal of Abnormal Psychology. 1988;97(3):251-264.
Wade TD, Kendler KS. The relationship between social support and major depression: cross-sectional, longitudinal, and genetic perspectives. Journal of Nervous and Mental Disease. 2000;188(5):251-258.
Bland RC, Newman SC, Orn H. Recurrent and nonrecurrent depression. Archives of General Psychiatry. 1986;43:1085-1089.
Zubenko GS, Zubenko WN, Spiker DG, Giles DE, Kaplan BB. Malignancy of recurrent, early-onset major depression: A family study. American Journal of Medical Genetics (Neuropsychiatric Genetics). 2001;105:690-699.
Birmaher B, Williamson DA, Dahl RE, Axelson DA, Kaufman J, Dorn LD, Ryan ND. Clinical presentation and course of depression in youth: Does onset in childhood differ from onset in adolescence? Journal of the American Academy of Child & Adolescent Psychiatry. 2004;43(1):63-70.
Lewinsohn PM, Rohde P, Seeley JR, Klein DN, Gotlib IH. Natural course of adolescent major depressive disorder in a community sample: Predictors of recurrence in young adults. American Journal of Psychiatry. 2000;157:1584-1591.
Gonzales LR, Lewinsohn PM, Clarke GN. Longitudinal follow-up of unipolar depressives: An investigation of predictors to relapse. Journal of Consulting and Clinical Psychology. 1985;53(4):461-469.
Zubenko GS, Zubenko WN, Spiker DG, Giles DE, Kaplan BB. Malignancy of recurrent, early-onset major depression: A family study. American Journal of Medical Genetics (Neuropsychiatric Genetics). 2001;105:690-699.
Klein DN, Lewinsohn PM, Rohde P, Seeley JR, Durbin CE. Clinical features of major depressive disorder in adolescents and their relatives: Impact on familial aggregation, implications for phenotype definition, and specificity of transmission. Journal of Abnormal Psychology. 2002;111(1):98-106.
Kendler KS, Neale MC, Kessler RC, Heath AC, Eaves LJ. Familial influences on the clinical characteristics of major depression: a twin study. Acta Psychiatrica Scandinavica. 1992;86(5):371-378.
Zubenko GS, Hughes HB, III, Stiffler JS, Zubenko WN, Kaplan BB. D2S2944 identifies a likely susceptibility locus for recurrent, early-onset, major depression in women. Molecular Psychiatry. 2002;7:460-467.
Philibert R, Caspers K, Langbehn D, Troughton EP, Yucuis R, Sandhu HK, Cadoret RJ. The association of the D2S2944 124 bp allele with recurrent early onset major depressive disorder in women. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics). 2003;121:39-43.
O’Leary DA, Lee AS. Seven year prognosis in depression: Mortality and readmission risk in the Nottingham ECT cohort. British Journal of Psychiatry. 1996;169:423-429.
Klein DN, Schatzberg AF, McCullough ME, Dowling F, Goodman D, Howland RH, Markowitz JC, Smith C, Thase ME, Rush AJ, LaVange L, Harrison WM, Keller MB. Age of onset in chronic major depression: Relations to demographic and clinical variables, family history, and treatment response. Journal of Affective Disorders. 1999;55:149-157.
Gilman SE, Kawachi K, Fitzmaurice GM, Buka SL. Socio-economic status, family disruption and residential stability in childhood: Relation to onset, recurrent, and remission of major depression. Psychological Medicine. 2003;33:1341-1355.
Kovacs M, Obrosky DS, Sherrill J. Developmental changes in the phenomenology of depression in girls compared to boys from childhood onward. Journal of Affective Disorders. 2003;74:33—48.
Birmaher B, Williamson DA, Dahl RE, Axelson DA, Kaufman J, Dorn LD, Ryan ND. Clinical presentation and course of depression in youth: Does onset in childhood differ from onset in adolescence? Journal of the American Academy of Child & Adolescent Psychiatry. 2004;43(1):63-70.
O’Leary D, Costello F, Gormley N, Webb M. Remission onset and relapse in depression: An 18-month prospective study of course for 100 first admission patients. Journal of Affective Disorders. 2000;57:159-171.
Kaminski KM, Garber J. Depressive spectrum disorders in high-risk adolescents: Episode duration and predictors of time to recovery. Journal of the American Academy of Child and Adolescent Psychiatry. 2002;41(4):410-418.
Barkow K, Maier W, Ustun TB, Gansicke M, Wittchen HU, Heun R. Risk factors for depression at 12-month follow-up in adult primary health care patients with major depression: an international prospective study. Journal of Affective Disorders. 2003;76:157-169.
Kessing LV. Severity of depressive episodes according to ICD-10: Prediction of risk of relapse and suicide. British Journal of Psychiatry. 2004;184:153-156.
O’Leary DA, Lee AS. Seven year prognosis in depression: Mortality and readmission risk in the Nottingham ECT cohort. British Journal of Psychiatry. 1996;169:423-429.
Alpert JE. Improving depression outcome: New concepts, strategies and technologies. Journal of Psychopharmacology. 2006;20(3 suppl):3-4.
Segal ZV, Pearson JL, Thase M. Challenges in preventing relapse in major depression: Report of a National Institute of Mental Health Workshop on state of the science of relapse prevention in major depression. Journal of Affective Disorders. 2003;77:97-108.
Wilhelm K, Parker G, Dewhurst-Savellis J, Asghari A. Psychological predictors of single and recurrent major depressive episodes. Journal of Affective Disorders. 1999;54:139.
Barkow K, Maier W, Ustun TB, Gansicke M, Wittchen HU, Heun R. Risk factors for depression at 12-month follow-up in adult primary health care patients with major depression: an international prospective study. Journal of Affective Disorders. 2003;76:157-169.
Giles DE, Jarrett RB, Biggs MM, Guzick DS, Rush AJ. Clinical predictors of recurrence in depression. American Journal of Psychiatry. 1989;146(6):764-767.
Coryell W, Endicott J, Keller M. Predictors of relapse into major depressive disorder in a nonclinical population. American Journal of Psychiatry. 1991;148(10):1353-1358.
Iosifescu DV, Bankier B, Fava M.. Impact of medical comorbid disease on antidepressant treatment of major depressive disorder. Curr Psychiatry Rep. 2004;6:193-201.
Kok G.D., Bockting C.L.H., Burger H., Hanning W., Pijnenborg G.H. Double trouble: does co-morbid chronic somatic illness increase risk for recurrence in depression? PLoS One. 2013:8(3):57510.
Gerrits M, Van Oppen, Leone S., Van Marvijk, Horst H., Penninx B. Pain, not chronic disease, is associated with the recurrence of depressive and anxiety disorders. BMC Psychiatr. 2014;14:187.
Abramson LY, Seligman ME, Teasdale JD. Learned helplessness in humans: Critiques and reformulation. Journal of Abnormal Psychology. 1978;87:49-74.
Beck A, Rush AJ, Shaw BF, Emery G. Cognitive Therapy of Depression. New York: The Guilford Press; 1979.
Iacoviello BM, Alloy LB, Abramson LY, Whitehouse WG, Hogan ME. The course of depression in individuals at high and low cognitive risk for depression: A prospective study. Journal of Affective Disorders. 2006;93:61-69.
Mongrain M, Blackburn S. Cognitive vulnerability, lifetime risk, and the recurrence of major depression in graduate students. Cognitive Therapy and Research. 2006;29(6):747-768.
Alloy LB, Abramson LY, Whitehouse WG, Hogan ME, Panzarella C, Rose DT. Prospective incidence of first onsets and recurrences of depression in individuals at high and low cognitive risk for depression. Journal of Abnormal Psychology. 2006;115(1):145-156.
Duggan CF, Sham P, Lee A, Minne C, Murray R. Neuroticism: A vulnerability marker for depression evidence from a family study. Journal of Affective Disorders. 1995;35:139-143.
Berlanga C, Heinze G, Torres M, Apiquian R, Caballero A. Personality and clinical predictors of recurrence of depression. Psychiatric Services. 1999;50(3):376-380.
Hirschfeld RM.. Guidelines for the long-term treatment of depression. J Clin Psychiatry. 1994;55(12 suppl):61-69.
Kaimaz N, Van Os J, Loonen A, Nolen W. Evidence that patients with single versus recurrent depressive episode are differentially sensitive to treatment discontinuation:a meta-analysis of placebo controlled randomized trials. J Clin Psychiatry. 2008;69;1423-1436.
Sim K, Lau WK, Sim J, Sum MY, Baldessarini RJ. Prevention of relapse and recurrence in adults with major depressive disorder: systematic review and meta-analyzes of controlled trials. Int J Neupsychopharmcol. 2015;1-13.
Baldessarini RJ, Lau WK, Sim J, Sum MY, Sim K. Suicidal Risks in Reports of Long-Term Controlled Trials of Antidepressants for Major Depressive Disorder II. International Journal of Neuropsychopharmacology. 2016.
Hirshfeld R. Long-term side effects of SSRIs: sexual dysfunction and weight gain. J Clin Psychiatry. 2003;64(suppl 18):20-24.
Doogan DP, Caillard V. Sertraline in the prevention of depression. Br J Psychiatry. 1992;160:217-222.
Keller MB. Maintenance phase efficacy of sertraline for chronic depression: a randomized controlled trial. JAMA. 1998;280:19:1665.
Lepine JP, Caillard V, Bisserbe JC, Troy S, Hotton JM, Boyer P. A randomized, placebo-controlled trial of sertraline for prophylactic treatment of highly recurrent major depressive disorder. Am J Psychiatry. 2004;161:836-842.
Wilson KCM, Mottram PG, Ashworth L, Abou-Saleh MT. Older community residents with depression: long-term treatment with sertraline. Randomized, double-blind, placebo-controlled study. Br J Psychiatr. 2003;182:492-497.
Rasmussen A, Lunde M, Poulsen DL, Sorensen K, Qvitzau S, Bech P. A double-blind, placebo-controlled study of sertraline in the prevention of depression in stroke patients. Psychosomatics. 2003;44(3):216-221.
Lustman PJ, Clouse RE, Nix BD, Freedland KE, Rubin EH, McGill GB, Williams MM, Gelenberg AJ, Ciechanovsky PS, Hirsch IB. Sertraline for prevention of depression recurrence in diabetes mellitus. A randomized, double-blind, placebo-controlled trial. Arch Gen Psychiatry. 2006;63:521-529.