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Smulevich A.B.

Mental Health Research Center, Moscow, Russia;
Sechenov First Moscow State Medical University, Moscow, Russia

Romanov D.V.

FGBU "Nauchnyĭ tsentr psikhicheskogo zdorov'ia" RAMN, Moskva;
NOKTs "Psikhosomaticheskaia meditsina" Pervogo Moskovskogo gosudarstvennogo meditsinskogo universiteta im. I.M. Sechenova, Moskva

Mukhorina A.K.

Mental Health Research Center, Moscow, Russia

Atadzhikova J.A.

Mental Health Research Center, Moscow, Russia

«Verschroben»-phenomenon in schizophrenia and schizophrenia spectrum disorders: aspects of systematics

Authors:

Smulevich A.B., Romanov D.V., Mukhorina A.K., Atadzhikova J.A.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2017;117(1): 5‑16

DOI: 10.17116/jnevro2017117115-16

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To cite this article:

Smulevich AB, Romanov DV, Mukhorina AK, Atadzhikova JA. «Verschroben»-phenomenon in schizophrenia and schizophrenia spectrum disorders: aspects of systematics. S.S. Korsakov Journal of Neurology and Psychiatry. 2017;117(1):5‑16. (In Russ.)
https://doi.org/10.17116/jnevro2017117115-16

 
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Objective. Psychopathological analysis and typological differentiation of «verschroben»-phenomenon as the full-blown syndrome of defect in schizophrenia and schizophrenia spectrum disorders. Material and methods. Fifty patients, 33 female and 17 male, mean age 44.8±8.5 years, with ICD-10 diagnosis of schizotypal disorder (F21) and residual schizophrenia (F20.5) were included in the study. Patients were examined using psychopathological and psychometric (SPQ-74) methods. Results and conclusion. There was clinical heterogeneity of the «verschroben» type defect: the differentiation of primary defect syndrome and the «second life» defect was confirmed. This typological classification is based not only on the differences in psychopathological symptoms and impaired social functioning but on the trajectory of the development of deficit syndromes related with the features of the course of endogenous disease. The typology would be useful for future studies of deficit changes in view of clinical prognosis, social context of schizophrenia spectrum disorders with negative «verschroben» type changes.

Keywords:

«verschroben»-phenomenon
schizophrenia
schizophrenia spectrum disorders
primary defect — syndrome
«second life» defect
deficit changes
autism

Authors:

Smulevich A.B.

Mental Health Research Center, Moscow, Russia;
Sechenov First Moscow State Medical University, Moscow, Russia

Romanov D.V.

FGBU "Nauchnyĭ tsentr psikhicheskogo zdorov'ia" RAMN, Moskva;
NOKTs "Psikhosomaticheskaia meditsina" Pervogo Moskovskogo gosudarstvennogo meditsinskogo universiteta im. I.M. Sechenova, Moskva

Mukhorina A.K.

Mental Health Research Center, Moscow, Russia

Atadzhikova J.A.

Mental Health Research Center, Moscow, Russia

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