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Alifirova V.M.

Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet, Tomsk, Russia

Zhukova N.G.

Siberian State Medical University, Tomsk, Russia

Zhukova I.A.

Siberian State Medical University, Tomsk

Latypova A.V.

Siberian State Medical University, Tomsk, Russia

Titova M.A.

Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet, Tomsk

Mironova Yu.S.

Siberian State Medical University, Tomsk, Russia

Izhboldina O.P.

Siberian State Medical University, Tomsk

Nikitina M.A.

Siberian State Medical University, Tomsk

Petrov V.A.

Siberian State Medical University, Tomsk, Russia

A role of the gastrointestinal tract microbiota in the pathogenesis of Parkinson’s disease

Authors:

Alifirova V.M., Zhukova N.G., Zhukova I.A., Latypova A.V., Titova M.A., Mironova Yu.S., Izhboldina O.P., Nikitina M.A., Petrov V.A.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2016;116(11): 174‑179

DOI: 10.17116/jnevro2016116111174-179

Views: 503

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To cite this article:

Alifirova VM, Zhukova NG, Zhukova IA, et al. . A role of the gastrointestinal tract microbiota in the pathogenesis of Parkinson’s disease. S.S. Korsakov Journal of Neurology and Psychiatry. 2016;116(11):174‑179. (In Russ.)
https://doi.org/10.17116/jnevro2016116111174-179

 
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Microbiota is a community of microorganisms, viruses, protozoa, colonizing the gut. There are tight phylogenetic relationships between the gut microbiota and the human body, the disturbance of which may lead to the CNS dysfunction as well as to the development of neurodegenerative diseases. This review focuses on general and specific aspects of the influence of gut microbiota on the pathogenesis of Parkinson’s disease (PD). Current theories and models of the relationship between microbiota and brain structures in PD are presented with a specific focus on neurochemical and immunological aspects of the problem.

Keywords:

neurodegenerative diseases
Parkinson’s disease
microbiota
microflora
the gastrointestinal tract

Authors:

Alifirova V.M.

Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet, Tomsk, Russia

Zhukova N.G.

Siberian State Medical University, Tomsk, Russia

Zhukova I.A.

Siberian State Medical University, Tomsk

Latypova A.V.

Siberian State Medical University, Tomsk, Russia

Titova M.A.

Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet, Tomsk

Mironova Yu.S.

Siberian State Medical University, Tomsk, Russia

Izhboldina O.P.

Siberian State Medical University, Tomsk

Nikitina M.A.

Siberian State Medical University, Tomsk

Petrov V.A.

Siberian State Medical University, Tomsk, Russia

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