Objective. To confirm the existence of a special variant of schizophrenia with bipolar affective disorders. Material and methods. The group of patients (n=30) with schizophrenia and bipolar affective disorder (BAD) with the lack of expressed and persistent hallucinations and/or delusions was studied. Extremely low levels of family adaptation, the severity of negative symptoms and the degree of its impact on social and occupational functioning confirmed the diagnosis of schizophrenia. Material and methods. Psychopathological and psychometric methods were used. Results. Bipolar depression was characterized by severity, atypical circadian rhythm, autochthonous asthenia, atypical symptoms, frequency of mixed depression, and accompanying comorbid symptoms as polymorphic phobias, symptoms of obsessive-compulsive disorders, and pathological body sensations (senestoalgia, senestopathy), subpsychotic episodes and the tendency to alcoholism. Conclusion. The results have shown that here is a need for the special variant of schizophrenia with bipolar affective disorders (outside BAD) in modern classifications of mental and behavioral disorders.