It was compared clinical characteristics of somatoform depressive disorders in patients of somatic and psychiatric in-patient departments (110 and 50 people, respectively). The somatic patients were divided into three groups: 1-st group - patients with masked depression (43.6%), 2-nd group - patients with somatic depression (30.9%), 3-rd group - patients with comorbid depression with a somatic disease (25.5%). The clinical presentations of the disease in the 1-st group are characterized by frontal somatic and autonomic disorders, with the presentations of depression corresponding to the term "depression without depression". In the clinical presentations of somatic depression (the 2-nd group) in addition to somatic and autonomic disorders, which mimic the therapeutic pathology, the affective disorders are presented by its reduced variants. In the clinical presentations of disease of the 3-rd group of patients, the symptoms of the somatic disorder are "reproduced" at the level of subjective complaints and symptoms of disease ("psychosomatic imitation"). Such distinction optimizes treatment due to the right choice of the priority clinical model within the framework of unitary psychosomatic disorder.