Interactions of constitutional character anomalies with endogenous disease are considered. Deformation of personality structure caused by the endogenous process in light of traditional conceptions (personality disorders (PD) as the perversion of inherent traits or the formation of new traits due to the schizophrenic defect) and current conceptions (PD as Axis II disorders, comorbid to psychopathological presentations of Axis I, "recovery" conception) are viewed on the basis of amplification mechanisms, "splitting" etc that do not principally alter the initial premorbid structure. These correlations do not explain all the diversity of interactions between the abnormal personality structure and endogenous process. A mechanism of this interaction is realized according to the complete "substitution" of constitutional properties by psychopathological presentations of the previous psychosis. The data obtained suggest that these clinical formations further do not undergo the reverse development but, maintaining its syndrome completeness, during the stabilization of the schizophrenic process reduce to the level of "minor psychiatric disorders", i.e. to the level of border-line psychiatric pathology and duplicate the psychosis. Just in these cases the state may be determined as PD acquired during the lifetime per se. Based on the matrix reflecting the residual signs of the process, the restoration of the personality is implemented.