Cognitive impairment in patients with arterial hypertension

Zaharov V.V.; Chernousov P.A.; Vekhova K.A.; Bogolepova A.N.

doi:https://doi.org/10.17116/jnevro202412404241

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Abstract:

Arterial hypertension (AH) is a leading risk factor for cardiovascular diseases including cerebrovascular complications. Strokes and/or vascular cognitive impairment (VCI) are considered as a clinical sign of brain damage as a target organ in hypertension. To identify and assess the severity of VCI, patients with hypertension should undergo a neuropsychological assessment. Neuroimaging confirm the vascular origin of cognitive impairment. Patient management should include antihypertensive therapy along with neuroprotection. Among different neuroprotective therapy, ethylmethylhydroxypyridine succinate (mexidol) is one of medication with serious evidence of clinical efficacy.

Keywords:

arterial hypertension

cognitive impairment

cerebral vascular disease

neuroprotection

ethylmethylhydroxypyridine succinate

mexidol

Authors:

Zaharov V.V.

Sechenov First Moscow State Medical University (Sechenov University)

ORCID: 0000-0002-8447-3264

Chernousov P.A.

Sechenov First Moscow Medical University (Sechenov University)

ORCID: 0000-0003-2143-1806

Vekhova K.A.

Sechenov First Moscow Medical University (Sechenov University)

ORCID: 0000-0003-0900-4721

Bogolepova A.N.

Pirogov Russian National Research Medical University;
Federal Center of Brain Research and Neurotechnologies of the Federal Medical Biological Agency

SPIN RSCI: 6775-0279
Scopus AuthorID: 6602240836
ORCID: 0000-0002-6327-3546

Received:

15.02.2024

Accepted:

16.02.2024

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References:

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