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Ryabov S.A.

Pirogov Russian National Research Medical University

Boyko A.N.

Pirogov Russian National Research Medical University;
Federal Center of Brain Research and Neurotechnologies of the Federal Medical Biological Agency

Belayeva I.A.

Pirogov Russian National Research Medical University;
National Research Medical Center for Rehabilitation and Balneology

Pehova Ya.G.

Pirogov Russian National Research Medical University;
National Research Medical Center for Rehabilitation and Balneology

Rachin A.P.

National Research Medical Center for Rehabilitation and Balneology

Medical rehabilitation of gait disorders in multiple sclerosis

Authors:

Ryabov S.A., Boyko A.N., Belayeva I.A., Pehova Ya.G., Rachin A.P.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2022;122(7‑2): 14‑18

DOI: 10.17116/jnevro202212207214

Read: 4822 times

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Table of contents

MEDICAL REHABILITATION OF GAIT DISORDERS IN MULTIPLE SCLEROSIS
MEDICAL REHABILITATION OF GAIT DISORDERS IN MULTIPLE SCLEROSIS

To cite this article:

Ryabov SA, Boyko AN, Belayeva IA, Pehova YaG, Rachin AP. Medical rehabilitation of gait disorders in multiple sclerosis. S.S. Korsakov Journal of Neurology and Psychiatry. 2022;122(7‑2):14‑18. (In Russ.)
https://doi.org/10.17116/jnevro202212207214

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова. Спецвыпуски (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))
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Использование инфографики авторами научных работ
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Abstract:

The most common and important consequence of multiple sclerosis (MS) is impaired walking, which limits daily activities and increases the risk of falling. This article provides an overview of the main non-pharmacological methods of medical rehabilitation of gait disorders in people with MS (aerobic and strength training, robotic technologies, orthotics and functional electrical stimulation), which have an evidence base on systematic reviews and meta-analyses. Special attention is paid to the approach to rehabilitation in people with severe disabilities. Methods for determining gait parameters using tests and high-tech devices are considered, which serve as the basis for the routine assessment of the domains of the International Classification of Functioning (ICF) and the effectiveness of interventions.

Keywords:

multiple sclerosis
rehabilitation
gait

Authors:

Ryabov S.A.

Pirogov Russian National Research Medical University

Boyko A.N.

Pirogov Russian National Research Medical University;
Federal Center of Brain Research and Neurotechnologies of the Federal Medical Biological Agency

Belayeva I.A.

Pirogov Russian National Research Medical University;
National Research Medical Center for Rehabilitation and Balneology

Pehova Ya.G.

Pirogov Russian National Research Medical University;
National Research Medical Center for Rehabilitation and Balneology

Rachin A.P.

National Research Medical Center for Rehabilitation and Balneology

Received:

06.05.2022

Accepted:

02.06.2022

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References:

  1. Amatya B, Khan F, Galea M. Rehabilitation for people with multiple sclerosis: an overview of Cochrane Reviews. Cochrane Database Syst Rev. 2019;1(1):CD012732. https://doi.org/10.1002/14651858.CD012732.pub2
  2. Heesen C, Böhm J, Reich C, et al. Patient perception of bodily functions in multiple sclerosis: gait and visual function are the most valuable. Mult Scler. 2008;14(7):988-991.  https://doi.org/10.1177/1352458508088916
  3. Larocca NG. Impact of walking impairment in multiple sclerosis: perspectives of patients and care partners. Patient. 2011;4(3):189-201.  https://doi.org/10.2165/11591150-000000000-00000
  4. Nilsagård Y, Gunn H, Freeman J, et al. Falls in people with MS--an individual data meta-analysis from studies from Australia, Sweden, United Kingdom and the United States. Mult Scler. 2015;21(1):92-100.  https://doi.org/10.1177/1352458514538884
  5. Hayes S, Galvin R, Kennedy C, et al. Interventions for preventing falls in people with multiple sclerosis. Cochrane Database Syst Rev. 2019;11(11):CD012475. Published 2019 Nov 28.  https://doi.org/10.1002/14651858.CD012475.pub2
  6. World Health Organization (WHO). International Classification of Functioning, Disability and Health (ICF). Accessed 1 March 2022. www.who.int/classifications/icf/en/
  7. Coenen M, Cieza A, Freeman J, et al. The development of ICF Core Sets for multiple sclerosis: results of the International Consensus Conference. J Neurol. 2011;258(8):1477-1488. https://doi.org/10.1007/s00415-011-5963-7
  8. Řasová K, Martinková P, Soler B, et al. Real-World Goal Setting and Use of Outcome Measures According to the International Classification of Functioning, Disability and Health: A European Survey of Physical Therapy Practice in Multiple Sclerosis. Int J Environ Res Public Health. 2020;17(13):4774. https://doi.org/10.3390/ijerph17134774
  9. Cofré Lizama LE, Khan F, Lee PV, Galea MP. The use of laboratory gait analysis for understanding gait deterioration in people with multiple sclerosis. Mult Scler. 2016;22(14):1768-1776. https://doi.org/10.1177/1352458516658137
  10. Liparoti M, Della Corte M, Rucco R, et al. Gait abnormalities in minimally disabled people with Multiple Sclerosis: A 3D-motion analysis study. Mult Scler Relat Disord. 2019;29:100-107.  https://doi.org/10.1016/j.msard.2019.01.028
  11. Greene BR, Rutledge S, McGurgan I, et al. Assessment and classification of early-stage multiple sclerosis with inertial sensors: comparison against clinical measures of disease state. IEEE J Biomed Health Inform. 2015;19(4):1356-1361. https://doi.org/10.1109/JBHI.2015.2435057
  12. Spain RI, Mancini M, Horak FB, Bourdette D. Body-worn sensors capture variability, but not decline, of gait and balance measures in multiple sclerosis over 18 months. Gait Posture. 2014;39(3):958-964.  https://doi.org/10.1016/j.gaitpost.2013.12.010
  13. Givon U, Zeilig G, Achiron A. Gait analysis in multiple sclerosis: characterization of temporal-spatial parameters using GAITRite functional ambulation system. Gait Posture. 2009;29(1):138-142.  https://doi.org/10.1016/j.gaitpost.2008.07.011
  14. Coca-Tapia M, Cuesta-Gómez A, Molina-Rueda F, Carratalá-Tejada M. Gait Pattern in People with Multiple Sclerosis: A Systematic Review. Diagnostics (Basel). 2021;11(4):584.  https://doi.org/10.3390/diagnostics11040584
  15. Feys P, Gijbels D, Romberg A, et al. Effect of time of day on walking capacity and self-reported fatigue in persons with multiple sclerosis: a multi-center trial. Mult Scler. 2012;18(3):351-357.  https://doi.org/10.1177/1352458511419881
  16. Sun R, McGinnis R, Sosnoff JJ. Novel technology for mobility and balance tracking in patients with multiple sclerosis: a systematic review. Expert Rev Neurother. 2018;18(11):887-898.  https://doi.org/10.1080/14737175.2018.1533816
  17. Alexander S, Peryer G, Gray E, et al. Wearable technologies to measure clinical outcomes in multiple sclerosis: A scoping review. Mult Scler. 2021;27(11):1643-1656. https://doi.org/10.1177/1352458520946005
  18. Abou L, Wong E, Peters J, et al. Smartphone applications to assess gait and postural control in people with multiple sclerosis: A systematic review. Mult Scler Relat Disord. 2021;51:102943. https://doi.org/10.1016/j.msard.2021.102943
  19. Leone C, Patti F, Feys P. Measuring the cost of cognitive-motor dual tasking during walking in multiple sclerosis. Mult Scler. 2015;21(2):123-131.  https://doi.org/10.1177/1352458514547408
  20. Rooney S, Ozkul C, Paul L. Correlates of dual-task performance in people with multiple sclerosis: A systematic review. Gait Posture. 2020;81:172-182.  https://doi.org/10.1016/j.gaitpost.2020.07.069
  21. Postigo-Alonso B, Galvao-Carmona A, Benítez I, et al. Cognitive-motor interference during gait in patients with Multiple Sclerosis: mixed Systematic Review. Neurosci Biobehav Rev. 2018;94:126-148.  https://doi.org/10.1016/j.neubiorev.2018.08.016
  22. Learmonth YC, Ensari I, Motl RW. Physiotherapy and walking outcomes in adults with multiple sclerosis: systematic review and meta-analysis. Physical Therapy Rev. 2016;21:3-6, 160-172.  https://doi.org/10.1080/10833196.2016.1263415
  23. Pearson M, Dieberg G, Smart N. Exercise as a therapy for improvement of walking ability in adults with multiple sclerosis: a meta-analysis. Arch Phys Med Rehabil. 2015;96(7):1339-1348.e7.  https://doi.org/10.1016/j.apmr.2015.02.011
  24. Kalb R, Brown TR, Coote S, et al. Exercise and lifestyle physical activity recommendations for people with multiple sclerosis throughout the disease course. Mult Scler. 2020;26(12):1459-1469. https://doi.org/10.1177/1352458520915629
  25. Ahmadi A, Arastoo AA, Nikbakht M, et al. Comparison of the Effect of 8 weeks Aerobic and Yoga Training on Ambulatory Function, Fatigue and Mood Status in MS Patients. Iran Red Crescent Med J. 2013;15(6):449-454.  https://doi.org/10.5812/ircmj.3597
  26. van den Berg M, Dawes H, Wade DT, et al. Treadmill training for individuals with multiple sclerosis: a pilot randomised trial. J Neurol Neurosurg Psychiatry. 2006;77(4):531-533.  https://doi.org/10.1136/jnnp.2005.064410
  27. Mañago MM, Glick S, Hebert JR, et al. Strength Training to Improve Gait in People with Multiple Sclerosis: A Critical Review of Exercise Parameters and Intervention Approaches. Int J MS Care. 2019;21(2):47-56.  https://doi.org/10.7224/1537-2073.2017-079
  28. Mount J, Dacko S. Effects of dorsiflexor endurance exercises on foot drop secondary to multiple sclerosis: a pilot study. Neuro Rehabilitation. 2006;21(1):43-50.  https://doi.org/10.3233/NRE-2006-21107
  29. Renfrew LM, Paul L, McFadyen A, et al. The clinical- and cost-effectiveness of functional electrical stimulation and ankle-foot orthoses for foot drop in Multiple Sclerosis: a multicentre randomized trial. Clin Rehabil. 2019;33(7):1150-1162. https://doi.org/10.1177/0269215519842254
  30. Casuso-Holgado MJ, Martín-Valero R, Carazo AF, et al. Effectiveness of virtual reality training for balance and gait rehabilitation in people with multiple sclerosis: a systematic review and meta-analysis. Clin Rehabil. 2018;32(9):1220-1234. https://doi.org/10.1177/0269215518768084
  31. Morelli N, Morelli H. Dual task training effects on gait and balance outcomes in multiple sclerosis: A systematic review. Mult Scler Relat Disord. 2021;49:102794. https://doi.org/10.1016/j.msard.2021.102794
  32. Pilloni G, Choi C, Shaw MT, et al. Walking in multiple sclerosis improves with tDCS: a randomized, double-blind, sham-controlled study. Ann Clin Transl Neurol. 2020;7(11):2310-2319. https://doi.org/10.1002/acn3.51224
  33. Aidar FJ, Gama de Matos D, de Souza RF, et al. Influence of aquatic exercises in physical condition in patients with multiple sclerosis. J Sports Med Phys Fitness. 2018;58(5):684-689.  https://doi.org/10.23736/S0022-4707.17.07151-1
  34. Tosun TA, Ipek Y, Ozdincler RA, Saip S. The efficiency of mirror therapy on drop foot in Multiple Sclerosis Patients. Acta Neurol Scand. 2021;143(5):545-553.  https://doi.org/10.1111/ane.13385
  35. Pilutti LA, Platta ME, Motl RW, Latimer-Cheung AE. The safety of exercise training in multiple sclerosis: a systematic review. J Neurol Sci. 2014;343(1-2):3-7.  https://doi.org/10.1016/j.jns.2014.05.016
  36. Jain A, Rosso M, Santoro JD. Wilhelm Uhthoff and Uhthoff’s phenomenon. Mult Scler. 2020;26(13):1790-1796. https://doi.org/10.1177/1352458519881950
  37. Sconza C, Negrini F, Di Matteo B, et al. Robot-Assisted Gait Training in Patients with Multiple Sclerosis: A Randomized Controlled Crossover Trial. Medicina (Kaunas). 2021;57(7):713-719.  https://doi.org/10.3390/medicina57070713
  38. Yeh SW, Lin LF, Tam KW, et al. Efficacy of robot-assisted gait training in multiple sclerosis: A systematic review and meta-analysis. Mult Scler Relat Disord. 2020;41:102034. https://doi.org/10.1016/j.msard.2020.102034
  39. Sattelmayer M, Chevalley O, Steuri R, Hilfiker R. Over-ground walking or robot-assisted gait training in people with.multiple sclerosis: does the effect depend on baseline walking speed and disease related disabilities? A systematic review and meta-regression. BMC Neurol. 2019;19(1):93-98.  https://doi.org/10.1186/s12883-019-1321-7
  40. Calabrò RS, Cassio A, Mazzoli D, et al. What does evidence tell us about the use of gait robotic devices in patients with multiple sclerosis? A comprehensive systematic review on functional outcomes and clinical recommendations. Eur J Phys Rehabil Med. 2021;57(5):841-849.  https://doi.org/10.23736/S1973-9087.21.06915-X
  41. Edwards T, Pilutti LA. The effect of exercise training in multiple sclerosis with severe mobility disability: A systematic review and future research directions. Mult Scler Relat Disord. 2017;16:31-39.  https://doi.org/10.1016/j.msard.2017.06.003
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