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Kovalzon V.M.

Severtsov Institute of Ecology and Evolution of Russian Academy of Sciences, Moscow, Russia

Functional neurochemistry of sleep—waking cycle in pathogenesis of neurological diseases

Authors:

Kovalzon V.M.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2017;117(4‑2): 5‑11

DOI: 10.17116/jnevro2017117425-11

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To cite this article:

Kovalzon VM. Functional neurochemistry of sleep—waking cycle in pathogenesis of neurological diseases. S.S. Korsakov Journal of Neurology and Psychiatry. 2017;117(4‑2):5‑11. (In Russ.)
https://doi.org/10.17116/jnevro2017117425-11

Подписка 2025 (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))
 
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Novel experimental data concerning the function of the basic cerebral neuromediator systems which take part in arousal reactions and waking maintenance are regarding in the review.

Keywords:

sleep
sleep—waking cycle
neuromediators
disorders of wakefulness and sleep

Authors:

Kovalzon V.M.

Severtsov Institute of Ecology and Evolution of Russian Academy of Sciences, Moscow, Russia

List of references:

  1. Kovalzon VM. Basics of somnology. Physiology and neurochemistry of the sleep-wakefulness cycle. M.: Binom. Laboratoria znaniy; 2011. (In Russ.).
  2. Kovalzon VM. Brain and sleep: from neurons — to the molecules. J Hjgh Nerv Activ. 2013;62(1):48-60. (In Russ.). https://doi.org/10.7868/S0044467713010073
  3. Kovalzon VM. Neurophysiology and neurochemistry of sleep. In: Levin YaI, Poluektov MG, eds. Somnology and sleep medicine, Selected lectures. M.: Medforum; 2013. (In Russ.).
  4. Liblau RS, Vassalli A, Seifinejad A, Tafti M. Hypocretin (orexin) biology and the pathophysiology of narcolepsy with cataplexy. Lancet Neurol. 2015;14:318-328. Accessed February 13, 2017. Available at: http://www.thelancet.com/neurology
  5. Kovalzon VM. Neurophysiology and neurochemistry of sleep. In: Poluektov M.G., ed. Somnology and sleep medicine. National handbook in memory of AM Vein and YaI Levin. M.: Medforum; 2016. (In Russ.).
  6. Tsujino N, Sakurai T. Role of orexin in modulating arousal, feeding, and motivation. Front Behav Neurosci. 2013;7;28. https://doi.org/10.3389/fnbeh.2013.00028
  7. Richter C, Woods IG, Schier AF. Neuropeptidergic control of sleep and wakefulness. Annu Rev Neurosci. 2014;37:503-531. https://doi.org/10.1146/annurev-neuro-062111-150447
  8. Gao X-B, Hermes G. Neural plasticity in hypocretin neurons: the basis of hypocretinergic regulation of physiological and behavioral functions in animals. Front Syst Neurosci. 2015;9:142. https://doi.org/10.3389/fnsys.2015.00142
  9. Torterolo P, Lagos P, Monti JM. Melanine-concentrating hormone — a new sleep factor? Front Neurosci. 2011;2;14. https://doi.org/10.3389/fneur.2011.00014
  10. Konadhode RR, Pelluru D, Shiromani PJ. Neurons containing orexin or melanin concentrating hormone reciprocally regulate wake and sleep. Frontiers in Systems Neuroscience. 2015;8;244. https://doi.org/10.3389/fnsys.2014.00244
  11. Kovalzon VM, Zavalko IM. The neurochemistry of the sleep—wakefulness cycle and Parkinson’s disease. Neurochemical Journal. 30(3):193-206. https://doi.org/10.7868/S1027813313030060
  12. Kovalzon VM. The role of Orexin/Hypocretin System of the Brain in the Regulation of Wakefulness and Sleep. Effective Pharmacotherapy. Neurology and Psychiatry. Special Issue «Sleep and Sleep Disorders-4». 2016;19:6-14. (In Russ.).
  13. Li S-B, Giardino WJ, de Lecea L. Hypocretins and Arousal. Curr Topics Behav Neurosci. 2016. https://doi.org/10.1007/7854_2016_58
  14. Lim MM, Szymusiak R. Neurobiology of Arousal and Sleep: Updates and Insights Into Neurological Disorders. Curr Sleep Medicine Rep. 2015;1:91-100. https://doi.org/10.1007/s40675-015-0013-0
  15. Kovalzon VM, Strygin KN. Neurochemical mechanisms of the regulation of sleep and wakefulness: the role of histamine receptors blockers in the treatment of insomnia. Effective Pharmacotherapy. Neurology and Psychiatry. Special issue «Sleep and sleep disorders». 2913;12:8-15. (In Russ.).
  16. Williams RH, Chee MJS, Kroeger D, Ferrari LL, Maratos-Flier E, Scammell TE, Arrigoni E. Optogenetic-Mediated Release of Histamine Reveals Distal and Autoregulatory Mechanisms for Controlling Arousal. The Journal of Neuroscience. 2014;4(17):6023-6029. https://doi.org/10.1523/JNEUROSCI.4838-13.2014
  17. Haas HL, Lin J-S. Waking with the hypothalamus. Pflugers Arch — Eur J Physiol. 2012;463:31-42. https://doi.org/10.1007/s00424-011-0996-4
  18. Kovalzon VM, Dolgikh VV. Regulation of sleep—wakefulness cycle. Nevrologicheskiy Zhurnal (Neurological Journal). 2016;21(6):316-322. (In Russ.). https://doi.org/10.18821/1560-9545-2016-21-6-316-322
  19. Kovalzon VM, Zavalko IM, Dorokhov VB. Parkinson’s disease, dopaminergic system of the brain and sleep regulation. In: Ugrumov M.V., ed. Neurodegenerative diseases: from genome to the entire organisms. V.1. M.: Nauchnyi Mir; 2014. (In Russ.).
  20. Brown RE, Basheer R, McKenna JT, Strecker RE, McCarley RW. Control of sleep and wakefulness. Physiol Rev. 2012;92:1087-1187. https://doi.org/10.1152/physrev.00032.2
  21. Schwartz MD, Kilduff TS. The Neurobiology of Sleep and Wakefulness. Pyiatr Clin N Am. 2015;38(4):615-644. https://doi.org/10.1016/j.psc.2015.07.002
  22. Garcia-Rill E, Luster B, Mahaffey S, Bisagno V, Urbano FJ. Pedunculopontine arousal system physiology — Implications for insomnia. Sleep Science. 2015;8:92-99. https://doi.org/10.1016/j.slsci.2015.06.002
  23. Kanda T, Tsujino1 N, Kuramoto E, Koyama Y, Susaki EA, Chikahisa S, Funato H. Sleep as a biological problem: an overview of frontiers in sleep research. J Physiol Sci. 2016;66:1-13. https://doi.org/10.1007/s12576-015-0414-3
  24. Xu M, Chung S, Zhang S, Zhong P, Ma C, Chang W-C, Weissbourd B, Sakai N, Luo L, Nishino S, Dan Y. Basal forebrain circuit for sleep-wake control. Nature Neuroscience. 2015;18:1641-1647. https://doi.org/10.1038/nn.4143
  25. Kaur S, Pedersen NP, Yokota S, Hur EE, Fuller PM, Lazarus M, Chamberlin NL, Saper CB. Glutamatergic Signaling from the Parabrachial Nucleus Plays a Critical Role in Hypercapnic Arousal. The Journal of Neuroscience. 2013;33(18):7627-7640. https://doi.org/10.1523/JNEUROSCI.0173-13.2013
  26. Weber F, Dan Y. Circuit-based interrogation of sleep control. Nature. 2016;538:1-59. https://doi.org/10.1038/nature197735
  27. Krone L, Frase L, Piosczyk H, Selhausen P, Zittel S, Jahn F, Kuhn M, Feige B, Mainberger F, Klöppel S, Riemann D, Spiegelhalder K, Baglioni C, Sterr A, Nissen C. Top-down control of arousal and sleep: Fundamentals and clinical implications. Sleep Medicine Reviews. 2017;31:17-24. https://doi.org/10.1016/j.smrv.2015.12.005
  28. Kovalzon VM. The role of histaminergic system of the brain in the regulation of sleep—wakefulness cycle. Human Physiology. 2013;39(6):574-583. https://doi.org/10.7868/S0131164613060088
  29. Luyster FS, Strollo PJ, Zee PC, Walsh J.K. Sleep: a health imperative. Sleep. 2012;35(6):727-734. https://doi.org/10.5665/sleep.1846

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