Prоgnosis of motor function recovery in ischemic stroke using diffusion tensor MRI

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Objective. To identify factors of motor recovery in ischemic stroke (IS) using diffusion tensor imaging (DTI). Material and methods. Forty-seven patients with IS were studied within 1—2, 7—8, 14—15, 20—21 days after stroke. The fractional anisotropy (FA) values of the pyramidal tract were measured in the posterior limb of the internal capsule, cerebral peduncle and pons. Relative values of FA (rFA) ratio (rFA=FA affected side/FA unaffected side) were assessed as well. Results. rFA≤0.7 in the cerebral peduncule and posterior limb of the internal capsule accurately predicted poor motor outcome in ischemic stroke. Conclusion. DTI can evaluate the motor deficit quantitatively and may predict the functional prognosis in patients with IS.

Keywords:

ischemic stroke

diffusion tensor imaging

fractional anisotropy

functional prognosis

Authors:

Maksimova M.Yu.

Federal State budgetary scientific Institution «Research Centre of Neurology», Moscow

Popova T.A.

Research Center of Neurology, Moscow, Russia

Konovalov R.N.

Nauchnyĭ tsentr nevrologii RAMN, Moskva

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