Clinical efficacy of high-intensity magnetic therapy and transcutaneous electrical nerve stimulation in patients with diabetes mellitus and distal polyneuropathy: a randomized study

Kulikova N.G.; Naidenov P.V.

doi:https://doi.org/10.17116/rbpdpm202520115

Kulikova N.G.

Sechenov First Moscow Medical University;
People’s Friendship University of Russia

ORCID: 0009-0007-0374-6763

Naidenov P.V.

Rozanov Hospital

ORCID: 0000-0003-1797-1324

Clinical efficacy of high-intensity magnetic therapy and transcutaneous electrical nerve stimulation in patients with diabetes mellitus and distal polyneuropathy: a randomized study

Authors:

Kulikova N.G., Naidenov P.V.

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Journal: Regenerative Biotechnologies, Preventive, Digital and Predictive Medicine. 2025;2(1): 5‑11

DOI: 10.17116/rbpdpm202520115

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To cite this article:

Kulikova NG, Naidenov PV. Clinical efficacy of high-intensity magnetic therapy and transcutaneous electrical nerve stimulation in patients with diabetes mellitus and distal polyneuropathy: a randomized study. Regenerative Biotechnologies, Preventive, Digital and Predictive Medicine. 2025;2(1):5‑11. (In Russ.)
https://doi.org/10.17116/rbpdpm202520115

Подписка 2026 Восстановительные биотехнологии, профилактическая, цифровая и предиктивная медицина (Regenerative Biotechnologies, Preventive, Digital and Predictive Medicine)

Использование инфографики авторами научных работ

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OBJECTIVE

To improve the treatment of diabetes mellitus and distal polyneuropathy considering data on dyslipidemic targets of neuropathy.

MATERIAL AND METHODS

A simple randomized study included 184 patients with diabetes mellitus (91 women and 93 men) and distal polyneuropathy who received different methods of physiotherapy (high-intensity magnetic therapy and transcutaneous electrical nerve stimulation) together with standard drug therapy (nonsteroidal anti-inflammatory drugs, analgesics).

RESULTS

In patients with diabetes and distal polyneuropathy, electroneuromyography revealed shifts in M-response and nerve conduction velocity, primarily in n. peroneus. The highest clinical effect was observed after high-intensity magnetic therapy alone (nerve conduction velocity in n. peroneus increased by 1.25 times) and high-intensity magnetic therapy with transcutaneous electrical nerve stimulation (nerve conduction velocity increased by 0.95 times). There was a significant correction of triglycerides and very low-density lipoproteins after high-intensity magnetic therapy with transcutaneous electrical nerve stimulation that was lower compared to high-intensity magnetic therapy alone.

CONCLUSION

Dyslipidemic shifts and ENMG changes are interrelated. This characterizes a negative trend of damage to thin and thick myelin fibers in patients with diabetes and distal polyneuropathy.

Keywords:

distal polyneuropathy

high-intensity magnetic therapy

transdermal electrical nerve stimulation

quality of life

lipid metabolism

Authors:

Kulikova N.G.

Sechenov First Moscow Medical University;
People’s Friendship University of Russia

ORCID: 0009-0007-0374-6763

Naidenov P.V.

Rozanov Hospital

ORCID: 0000-0003-1797-1324

Received:

20.12.2024

Accepted:

24.01.2025

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References:

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