The influence of intravenous ozone therapy on the electrophysiological properties of myocardium during combined treatment of the patients presenting with arterial hypertension

Gimaev R.Kh.

Ul'ianovskiĭ gosudarstvennyĭ universitet

Drapova D.P.

Ul'ianovskiĭ gosudarstvennyĭ universitet

Skvortsov D.Iu.

Ul'ianovskiĭ gosudarstvennyĭ universitet

Olezov N.V.

Ul'ianovskiĭ gosudarstvennyĭ universitet

The influence of intravenous ozone therapy on the electrophysiological properties of myocardium during combined treatment of the patients presenting with arterial hypertension

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Gimaev R.Kh., Drapova D.P., Skvortsov D.Iu., Olezov N.V.

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Journal: Problems of Balneology, Physiotherapy and Exercise Therapy. 2013;90(6): 48‑51

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Gimaev RKh, Drapova DP, Skvortsov DIu, Olezov NV. The influence of intravenous ozone therapy on the electrophysiological properties of myocardium during combined treatment of the patients presenting with arterial hypertension. Problems of Balneology, Physiotherapy and Exercise Therapy. 2013;90(6):48‑51. (In Russ.)

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The present investigation included 65 patients (36 men and 29 women of the mean age of 51.3±6.7 years) presenting with grade I-II arterial hypertension (AH) and undergoing intravenous ozone therapy in combination with the intake of antihypertensive preparations. ECG studies showed that a course of ozone therapy decreases the degree of in homogeneity of intra-myocardial electrophysiological processes in the patients with AH as apparent from reduced dispersion of P-wave and corrected QT-interval. Analysis of the results of high-resolution ECG revealed a significant decrease in the frequency of ventricular late potentials from 29.2% (19 patients) to 13.8% (9 patients) (χ2=4.5; p=0.03) whereas the decrease in the frequency of atrial late potentials was insignificant, from 40% (26 patients) to 29.2% (19 patients) (χ2=1.67; p=0.19). The results of spectral-temporal mapping indicate that a course of ozone therapy resulted in a significant decrease of the total number of local peaks in the QRS complex and the number of peaks with low-amplitude and high-frequency characteristics.

Keywords:

arterial hypertension

intravenous ozone therapy

electrophysiological remodeling of the heart

Authors:

Gimaev R.Kh.

Ul'ianovskiĭ gosudarstvennyĭ universitet

Drapova D.P.

Ul'ianovskiĭ gosudarstvennyĭ universitet

Skvortsov D.Iu.

Ul'ianovskiĭ gosudarstvennyĭ universitet

Olezov N.V.

Ul'ianovskiĭ gosudarstvennyĭ universitet

List of references:

Grachev S.V., Ivanov G.G., Syrkin A.L. Novye metody elektrokardiografii. M.: Tekhnosfera; 2007. 552 s. [The new methods in electrocardiography. M.: Tekhnosfera; 2007. 552 p.]. [In Russian].
Tomaselli G.F., Marban E. Electrophysiological remodeling in hypertrophy and heart failure. Cardiovasc. Res. 1999; 42 (2): 270-83.
Balkarov I.M., Shonichev D.G., Kozlova V.G. Nekotorye podkhody k povysheniyu kachestva lecheniya patsientov s arterial'noy gipertoniey [Selected approaches to the improvement of the quality of health care in the patients presenting with arterial hypertension]. Terapevticheskiy arkhiv. 2000; 1: 47-51. [In Russian].
Agadzhanyan N.A., Pogosyan L.I., Suvorova I.A., Ryazanov N.V., Daraeva T.V. Effektivnost' ozonoterapii v komplekse sanatorno-kurortnogo lecheniya bol'nykh distsirkulyatornoy entsefalopatiey [ The effectiveness of ozonotherapy included in the spa and resort-based combined treatment of the patients presenting with dyscirculatory encephalopathy]. Vestnik vosstanovitel'noy meditsiny. 2005; 3: 44. [In Russian].
Maslennikov O.V., Kontorshchikova K.N. Ozonoterapiya: Vnutrennie bolezni. Nizhniy Novgorod: Izd-vo Vektor - TiS; 2003. 132 s. [Ozonotherapy: Internal diseases. Nizhniy Novgorod: Izd-vo Vektor - TiS; 2003. 132 p.]. [In Russian].
Odinak M.M. Ozonovye vanny v sanatorno-kurortnom lechenii bol'nykh ishemicheskoy bolezn'yu serdtsa [The role of ozone baths in the spa and resort-based treatment of the patients presenting with coronary heart disease]. Voprosy kurortologii, fizioterapii i lechebnoy fizicheskoy kul'tury. 2001; 1: 6-8. [In Russian].
Struchkov P.V. Ispol'zovanie ozonoterapii v kompleksnom lechenii bol'nykh distsirkulyatornoy entsefalopatiey [The application of ozonotherapy for the combined treatment of the patients presenting with dyscirculatory encephalopathy]. . Voprosy kurortologii, fizioterapii i lechebnoy fizicheskoy kul'tury. 2008; 2: 10-13. [In Russian].
Boytsov S.A., Grishaev S.L., Tishchenko O.L., Solntsev V.N., Pinegin A.N. Novyy metod opisaniya rezul'tatov spektral'no-vremennogo kartirovaniya EKG VR i otsenka ego diagnosticheskoy effektivnosti [The new method for the description of the results of spectral and temporal mapping of high-resolution ECG and the assessment of its diagnostic effectiveness]. Vestnik aritmologii. 1999; 14: 25-29. [In Russian].
Belyanin I.I. Biologicheskie i lechebnye svoystva ozona. M.; 1998. [The biological and therapeutic properties of ozone. M.: 1998]. [In Russian].
Rilling S., Viebahn R. The use of ozone in medicine. Heidelberg: Haug Publishers; 1987. 350 p.
Razumovskiy S.D., Zaykov T.E. Ozon i ego reaktsii s organicheskimi soedineniyami. M.: Nauka; 1974. 322 s. {Ozone and its reactions with organic compounds. M.: Nauka; 1974. 322 p.]. [In Russian].
Chernyshev A.V., Sorochinskaya I.N. Effektivnost' primeneniya ozonoterapii i obshchikh serovodorodnykh vann v kompleksnom sanatorno-kurortnom lechenii bol'nykh s metabolicheskim sindromom [The effectiveness of application of ozonotherapy and general hydrogen sulfide baths for the combined spa and resort-based treatment of the patients presenting with metabolic syndrome]. Vestnik vosstanovitel'noy meditsiny. 2012; 6: 39-42. [In Russian].
Shlyakhto E.V., Konradi A.O. Prichiny i posledstviya aktivatsii simpaticheskoy nervnoy sistemy pri arterial'noy gipertenzii [The causes and consequences of activation of the sympathetic nervous system associated with arterial hypertension]. Arterial'naya gipertenziya. 2003; 9 (3): 81-88. [In Russian].
Sunnen G.V. Ozon in medicine. In: Proceedings of the IX world congress of ozone. vol. 3. New York; 1989: 1-16.

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